World Equity Markets and COVID-19: Immediate Response and Recovery Prospects

Following the spread of the COVID-19 pandemic, most global equity markets experienced significant falls. Recognizing the severe economic impacts of the pandemic, from mid-March, many governments announced unprecedented economic rescue packages, which appear to restore investors’ confidence, given the recoveries in most stock markets. However, the recovery performance significantly varies across countries. This paper provides an empirical analysis of how much of the recovery performance observed in equity markets can be explained by the size and types of rescue packages declared by countries. We find that among different types, fiscal stimulus supports seem to be a stronger predictor of equity market recovery performance. We also find that the severity of the outbreak, reliance more on natural resource and tourism revenues are negatively correlated with countries’ stock market recovery performance

Extended High Frequency Audiometry in Polycystic Ovary Syndrome

Objective. Polycystic ovarian syndrome (PCOS) is the most common endocrine disorder affecting 5–10% of women in reproductive age. Insulin resistance, dyslipidemia, glucose intolerance, hypertension, and obesity are metabolic disorders accompanying the syndrome. PCOS is a chronic proinflammatory state and the disease is associated with endothelial dysfunction. In diseases with endothelial damage, hearing in high frequencies are mostly effected in early stages. We evaluated extended high frequency hearing loss in PCOS patients. Material Methods. Forty women diagnosed as PCOS and 25 healthy controls were included in this study. Age and BMI of PCOS and control groups were comparable. Each subject was tested with low (250–2000 Hz), high (4000–8000 Hz), and extended high frequency audiometry (8000–20000). Hormonal and biochemical values including LH, LH/FSH, testosterone, fasting glucose, fasting insulin, HOMA-I, and CRP were calculated. Results. PCOS patients showed high levels of LH, LH/FSH, testosterone, fasting insulin, glucose, HOMA-I, and CRP levels. The hearing thresholds of the groups were similar at frequencies of 250, 500, 1000, 2000, and 4000 Hz; statistically significant difference was observed in 8000–14000 Hz in PCOS group compared to control group. Conclusion. PCOS patients have hearing impairment especially in extended high frequencies. Further studies are needed to help elucidate the mechanism behind hearing impairment in association with PCOS

Association of Acromegaly and Multiple Myeloma: A Case Report

Malignancy is an important cause of mortality in acromegaly. Hematological malignancies are very rare in acromegaly. Here, we report an 80-yearold patient with acromegaly and multiple myeloma. Patient died within a month of diagnosis. Previous studies have shown that growth hormone and somatomedin-C activate B lymphocyte and somatomedin-C receptors are found in multiple myeloma cells. Possible effects of growth hormone and somatomedin-C on multiple myeloma progression are discussed in the light of the relevant literature.Akromegali hastalarında malignite önemli bir mortalite nedenidir. Hematolojik maligniteler akromegali hastalarında oldukça nadiridir. Burada eş zamanlı akromegali ve multiple myeloma tanısı konulan 80 yaşında bir olgu sunuldu. Olgu tanıdan sonraki bir ay içinde kaybedildi. Büyüme hormonu ve somatomedin-C ‘nin B lenfositleri aktive ettiği ve somotomedin-C reseptörlerinin multiple myeloma hücrelerinde bulunduğu daha önceden gösterilmiştir. Büyüme hormonu ve somatomedin-C ‘nin myeloma progresyonu üzerine olan bu olası etkileri literatür eşliğinde tartışıldı

Akromegali ve multiple myeloma birlikteliǧi: Bir olgu sunumu

Malignancy is an important cause of mortality in acromegaly. Hematological malignancies are very rare in acromegaly. Here, we report an 80-yearold patient with acromegaly and multiple myeloma. Patient died within a month of diagnosis. Previous studies have shown that growth hormone and somatomedin-C activate B lymphocyte and somatomedin-C receptors are found in multiple myeloma cells. Possible effects of growth hormone and somatomedin-C on multiple myeloma progression are discussed in the light of the relevant literature.Akromegali hastalarında malignite önemli bir mortalite nedenidir. Hematolojik maligniteler akromegali hastalarında oldukça nadiridir. Burada eş zamanlı akromegali ve multiple myeloma tanısı konulan 80 yaşında bir olgu sunuldu. Olgu tanıdan sonraki bir ay içinde kaybedildi. Büyüme hormonu ve somatomedin-C ‘nin B lenfositleri aktive ettiği ve somotomedin-C reseptörlerinin multiple myeloma hücrelerinde bulunduğu daha önceden gösterilmiştir. Büyüme hormonu ve somatomedin-C ‘nin myeloma progresyonu üzerine olan bu olası etkileri literatür eşliğinde tartışıldı

Fascin expression in cholesteatoma: correlation with destruction of the ossicular chain and extent of disease

ObjectiveFascin is an actin-bundling protein found in cell membrane protrusions and increases cell motility. The expression of fascin in epithelial neoplasms has been described only recently. No data are available concerning the role of this protein in invasive cholesteatoma. Thus, we investigated the expression of fascin in cholesteatoma tissue and the relationship between fascin expression and intraoperative evaluation of the destruction of the ossicular chain and extent of disease