Toward a Theory of the Primo Vascular System: A Hypothetical Circulatory System at the Subcellular Level

This paper suggests a theoretical framework for the primo vascular system (PVS), a hypothetical circulatory system, in which extracellular DNA microvesicles interact to form and break down cell structures. Since Bonghan Kim reported the existence of Bonghan ducts and the SNU research team reinvestigated and named it the PVS, there has been series of studies trying to examine its structure and functions. In this paper, we hypothesize that the PVS is the network system in which extracellular DNA microvesicles circulate and interact at the subcellular level, forming and breaking down cell structures. This idea integrates A. Béchamp’s idea of microzymas and Bonghan Kim’s idea of sanals. A proof of this idea may complement modern medical theory, perhaps providing an essential clue for an alternative solution dealing with modern healthcare problem

History of Bioelectrical Study and the Electrophysiology of the Primo Vascular System

Background. Primo vascular system is a new anatomical structure whose research results have reported the possibility of a new circulatory system similar to the blood vascular system and cells. Electrophysiology, which measures and analyzes bioelectrical signals tissues and cells, is an important research area for investigating the function of tissues and cells. The bioelectrical study of the primo vascular system has been reported by using modern techniques since the early 1960s by Bonghan Kim. This paper reviews the research result of the electrophysiological study of the primo vascular system for the discussion of the circulatory function. We hope it would help to study the electrophysiology of the primo vascular system for researchers. This paper will use the following exchangeable expressions: Kyungrak system = Bonghan system = Bonghan circulatory system = primo vascular system = primo system; Bonghan corpuscle = primo node; Bonghan duct = primo vessel. We think that objective descriptions of reviewed papers are more important than unified expressions when citing the papers. That said, this paper will unify the expressions of the primo vascular system

Posterior auricular pain caused by the trigger points in the sternocleidomastoid muscle aggravated by psychological factors -A case report-

Psychological factors play a significant role in the pain mechanism, and psychological approaches may be useful complements to traditional medical and surgical treatments in pain management. The authors report a case of recurrent severe posterior auricular pain caused by trigger points in the right sternocleidomastoid muscle and influenced by stressful psychological situations (e.g., family affairs, job loss) in a 50-year-old man

Relationship between Arachidonate 5-Lipoxygenase-Activating Protein Gene and Peripheral Arterial Disease in Elderly Patients Undergoing General Surgery: A Retrospective Observational Study

Patients with peripheral arterial disease (PAD) are at a higher risk of developing postoperative complications. Arachidonate 5-lipoxygenase-activating protein (ALOX5AP) plays an important role in atherosclerosis pathogenesis. In this study, the relationship between PAD and several single nucleotide polymorphisms (SNPs) of ALOX5AP (rs17216473, rs10507391, rs4769874, rs9551963, rs17222814, and rs7222842) was investigated in elderly patients undergoing general surgery. The medical records of 129 patients aged > 55 years who underwent elective general surgery between May 2018 and August 2019 were retrospectively reviewed. The A/A in rs17216473, A/A in rs10507391, G/G in rs4769874, and A/A in rs9551963 were calculated as 0 points and the rest as 1 point to define the genetic risk score. The prevalence of PAD tended to increase with higher genetic risk scores (patients had less ALOX5AP gene polymorphism of A/A in rs17216473, A/A in rs10507391, G/G in rs4769874, or A/A in rs9551963) (p = 0.005). Multivariate logistic regression analysis revealed that the genetic risk score (p = 0.009) and age (p = 0.007) were positively correlated with the prevalence of PAD. Genetic polymorphisms of ALOX5AP and age were associated with the prevalence of PAD in this study

Deep hypothermic circulatory arrest for thoracoabdominal aortic aneurysm repair in a patient with a large intracranial anterior communicating artery aneurysm

Abdominal aortic aneurysms occasionally occur concomitantly with an intracranial artery aneurysm (ICA). The association of an ICA with a thoracoabdominal aortic aneurysm (TAAA) is relatively rare. A patient with this condition is presented. Coiling of the ICA was not an option preoperatively because of the dissected false lumen of the TAAA, rendering a femoral artery approach impossible. The TAAA was repaired during deep hypothermic circulatory arrest.Baraka AS, 2008, J CARDIOTHOR VASC AN, V22, P173, DOI 10.1053/j.jvca.2007.03.010Fukuda S, 2007, BRIT J ANAESTH, V99, P10, DOI 10.1093/bja/aem140DOROTTA I, 2007, SEMIN CARDIOTHORAC V, V11, P66Bendok BR, 2005, NEUROSURGERY, V56, P626, DOI 10.1227/01.NEU.0000154820.28342.38DRUMMOND JC, 2005, MILLERS ANESTHEIA, P2127LEVY EI, 2002, NEUROSURGERY, V51, P335Kanai H, 2001, NEUROL MED-CHIR, V41, P260Connolly ES, 1998, NEUROSURG CLIN N AM, V9, P681Bachet J, 1996, EUR J CARDIO-THORAC, V10, P817YERLIOGLU ME, 1995, J THORAC CARDIOV SUR, V110, P1470GUGLIELMI G, 1994, NEUROSURG CLIN N AM, V5, P427PERKO MJ, 1993, ANN VASC SURG, V7, P113WILLIAMS MD, 1991, ANN THORAC SURG, V52, P1069NORRGARD O, 1987, ACTA NEUROCHIR, V87, P34CURTIS J, 1968, J AMER MED ASSOC, V203, P982