Neuroimaging in contact sports: Determining brain fitness before and after a bout

Background: Professional boxing and mixed martial arts (MMA) are popular contact sports with high risk for both acute and chronic traumatic brain injury (TBI). Although rare, combatants have died in the ring/cage or soon after the completion of the bout. The cause of death in these cases is usually acute subdural hematoma, acute epidural hematoma, subarachnoid haemorrhage, intracranial haemorrhage, or second-impact syndrome (SIS). Neuroimaging or brain imaging is currently included in the process of registering for a license to fight in a combat sport in most states in the United States and around the world. However, the required imaging specifics and frequency vary.Discussion: Neuroimaging serves two distinct roles in the individualised care of a combatant, representing a step towards personalised medicine and individual risk stratification. Neuroimaging prior to licensure helps to identify and/or exclude coincidental or clinically suspected brain lesions which may pose a risk for rupture, bleeding or other catastrophic and important brain injury. Neuroimaging in the immediate aftermath of a bout primarily serves to rule out acute traumatic brain injury. Neuroimaging may also be carried out to assess for evidence of structural brain injury which may make a combatant more likely to express late-life neuropsychiatric sequelae of brain injury, such as chronic traumatic encephalopathy. As such, neuroimaging plays a prognostic role and aids in the determination of whether the combatant should be allowed to continue to participate in future bouts or not.Conclusion: Currently there are no established neuroimaging guidelines for contact sports. Standardising neuroimaging guidelines both for licensure as well as neuroimaging modality, and protocols to assess for both acute and chronic traumatic brain injury. This will assist in protecting the combatant’s health and safety, both in the ring/cage, and after their professional careers have ended. Some suggested guidelines are provided based on currently available medical literature. It is recommended that these guidelines be debated vigorously by the scientific community and that evidence-based guidelines be developed by the medical community in conjunction with professional boxing and MMA governing bodies.Keywords: boxing, MMA, traumatic brain injury, chronic traumatic encephalopath

The bottomside parameters <i>B0</i>, <i>B1</i> obtained from incoherent scatter measurements during a solar maximum and their comparisons with the IRI-2001 model

International audienceHigh resolution electron density profiles (Ne) measured with the Arecibo (18.4 N, 66.7 W), Incoherent Scatter radar (I. S.) are used to obtain the bottomside shape parameters B0, B1 for a solar maximum period (1989?90). Median values of these parameters are compared with those obtained from the IRI-2001 model. It is observed that during summer, the IRI values agree fairly well with the Arecibo values, though the numbers are somewhat larger during the daytime. Discrepancies occur during winter and equinox, when the IRI underestimates B0 for the local times from about 12:00 LT to about 20:00 LT. Furthermore, the IRI model tends to generally overestimate B1 at all local times. At Arecibo, B0 increases by about 50%, and B1 decreases by about 30% from solar minimum to solar maximum

Status of Bioprospecting of Marine Molluscs in India

Continuous pressure on the environment arising inevitably or otherwise out of technological progress and human population growth has made it necessary to place a commodity value on biodiversity (Randall, 1991)

Solar Cycle variations of ƒoF2 from IGY to 1990

Noontime monthly median values of F2-layer critical frequency ƒoF2 (m) for some ionospheric stations representing low- and mid-latitudes are examined for their dependence on solar activity for the years 1957 (IGY) to 1990. This is the period for which ionospheric data in digital form is available in two CD-ROMs at the World Data Center, Boulder. It is observed that at mid-latitudes, foF2 (m) shows nearly a linear relationship with R12 (the 12-month running average of the Zurich sunspot number), though this relation is nonlinear for low-latitudes. These results indicate some departures from the existing information often used in theoretical and applied areas of space research

Effect of immunostimulant on enhancement of the immune response of kuruma shrimp Marsupenaeus japonicus and its resistance against White Spot Syndrome Virus (WSSV)

An experiment of 45 days duration to test the efficacy of the Vibrio alginolyticus as an immunostimulant was conducted in Marsupenaeus japonicus against white spot syndrome virus (WSSV) infection, considered as one of the serious pathogens of shrimps. The shrimps were fed with the experimental diets coated with different concentrations of bacteria of 17 ml / kg feed and 10 % of animal body wt. They were challenged with WSSV to assess the increase in survival rate and growth if any due to immune enhancement. Another group of shrimp was used for drawing the haemolymph to estimate the increase in the level of prophenoloxidase activity. Samplings for the above said analysis were carried out at 15 days interval for a period of 45 days. The highest prophenoloxidase activity (39.78 with sand substrate-T1) and the highest survival rate (66.66 % with sand substrate-T1) and highest growth rate (7.04 % in 17ml/kg- with sand substrate-T1) were recorded in experimental diet (17 ml / kg feed). Hence the 17 ml / kg feed of Vibrio alginolyticus formalin killed added to the diet could be an eco-friendly and economically viable immunostimulant for penaeid shrimps

Diurnal and seasonal variations of <i>hm</i>F2 deduced from digitalionosonde over New Delhi and its comparison with IRI 2001

International audienceUsing digital ionosonde observations at a low mid-latitude station, New Delhi (28.6°N, 77.2°E, dip 42.4°N), we have derived hourly monthly values of hmF2 (the real height corresponding to the peak electron density in the F2-region), employing both the Dudeney (1983) and Bilitza (1990) empirical formulations for the period from January 2001 to August 2002. The diurnal and seasonal variations of hmF2 are analyzed. Further, to assess the predictability of the latest available model, International Reference Ionosphere, (IRI-2001), we have obtained the median values of hmF2 derived from M(3000)F2 for each hour during different seasons and compare these with the model. Our results show that both the Dudeney (1983) and Bilitza (1990) formulations reveal more or less a similar diurnal trend of hmF2, with higher values around midnight and lower during sunrise, in all the seasons. It is also noted that the hmF2 shows a larger variability around midnight than by daytime, in all the seasons. Further, the study shows that median values of observed hmF2, using both formulations, are somewhat larger than those predicted by the IRI, in all seasons and at all local times. During summer, the IRI values agree comparatively well with the observations, especially during daytime. Major discrepancies occur when the IRI underestimates observed hmF2 for local times from about 14:00 LT to 18:00 LT and 04:00 LT to 05:00 LT during winter and equinox, where the percentage deviation of the observed hmF2 values with respect to the IRI model varies from 15 to 25%. The difference between the model and observations, outside this time period, remains less than 20% during all the seasons. Key words. Ionosphere (modelling and forecasting; equatorial ionosphere

Boxer safety, and the relationship between the referee and the ringside physician

Both the referee and the ringside physician areentrusted with the safety of the boxer in the ring. TheUniform Boxing Rules (approved August 25, 2001,Amended August 2, 2002, Amended July 3, 2008)recognise the referee as the sole arbiter of a bout andthe only individual authorised to stop a contest. Unified rules ofmixed martial arts (MMA) and some boxing commissions recogniseboth the referee and the ringside physician as arbiters of a fight, andthe only individuals authorised to enter the fight area at any timeduring competition and stop a fight when the combatant’s safetyis compromised. Irrespective of who stops the fight, the stoppageshould be timely and fair to the combatants and their corners; apremature stoppage is unfair to the boxers, their corners, the promoterand the public, while a fight stopped too late risks serious injury andeven death of the boxer.[1]Stoppage from inside th