Optimal operation and marginal costs in simple trigeneration systems including thermal energy storage

The development of high-efficiency energy systems is a pressing issue nowadays, motivated by economic, environmental, and social aspects. Trigeneration systems allow for the rational use of energy by means of appropriate energy integration and provide greater operational flexibility, which is particularly interesting for buildings, often characterized by variable electricity, heating, and cooling demands. The benefits of trigeneration systems can be enhanced by the incorporation of thermal energy storage (TES), which decouples production and consumption. This paper analyses the operation of a simple trigeneration system including TES. The optimal operation is obtained by a linear programming model that minimizes the total variable cost. A thermoeconomic analysis based on marginal cost assessment of the internal flows and final products of the system is carried out, allowing to explain the optimal operation of the system and the role of the TES in achieving the optimal solution. The analysis unravels the marginal cost formation process, presenting a clear route from the final products obtained to the resources consumed. This information can aid the design of new plants, the retrofit of existing ones, and the operational management to achieve the minimum operational cost

Optimal design of trigeneration systems for buildings considering cooperative game theory for allocating production cost to energy services

In the design of trigeneration plants for buildings, two fundamental issues must be addressed: the synthesis of the plant configuration (installed technologies and capacity, etc.) and the operational planning. Given the variety of technology options available and great diurnal and annual fluctuations in energy demands, finding the optimal supply system of energy services is a complex task. Cost allocation in multi-product systems requires special attention because the way in which allocation is made will affect the prices of the final products and, consequently, the consumers' behaviour. When a polygeneration plant is designed to serve different products, it is possible to achieve a lower total cost. However, if potential consumers are free to participate, the system's management should ensure that every participant shares the benefit of joint production. In trigeneration systems this implies that all consumers should achieve, at least, a lower cost for their demanded energy services than operating separately. The present work proposes a Mixed Integer Linear Programming model to determine the optimal configuration of trigeneration systems that must cover the energy demands of electricity, heating and cooling of a residential complex located in Zaragoza, Spain. The model considers the possibility of using a set of proposed alternative technologies within a superstructure and considers the optimal operation throughout a typical meteorological year. The objective function to be minimized is the total annual cost. The results indicate that compared to consumers standing alone, the optimal trigeneration system can achieve 10.6% cost saving. Ten different cost assessment methods to the three final energy products of the analyzed trigeneration system are rigorously compared. Cooperative game theory shows that all consumers benefit. Using the Shapley values as the distribution criterion, the savings for electricity, heating and cooling consumers are 4.8%, 20.9% and 11.1%, respectively

Tackling thermal integration in the synthesis of polygeneration systems for buildings

A novel methodology is proposed for the synthesis of polygeneration systems in tertiary sector buildings with detailed thermal integration. The methodology involves a systematic approach that combines Pinch Analysis, mathematical programming, and the definition of a superstructure with thermal flexibility whereby mass flows can exchange heat in various temperature intervals. With the detailed characterization of the thermal energy flows associated with the thermal energy technologies and services to be supplied to the building, the optimization procedure provides a more realistic system configuration, ensures that thermodynamic principles are satisfied, and allows for synergies and potential benefits to emerge. The methodology is first introduced through a simple example of a gas engine-based energy system, highlighting the necessity of a detailed characterization of the hot and cold flows regarding their quantity and quality levels. Then, the approach is applied to the case study of a Brazilian university hospital that requires electricity, steam, hot water, and chilled water. The optimization is formulated as a multi-period mixed integer linear programming model that minimizes the total annual cost of installing and operating the system using local-based data. The results show the technical and economic interest of deploying cogeneration gas engines to cover electricity and thermal energy services. Besides, a strong synergy is observed between the cogeneration gas engine and the single-effect absorption chiller. Thus, it is demonstrated how a preliminary analysis of thermal integration opportunities must be an integral part of the optimal synthesis of energy supply systems

Comparative analysis and design of a solar-based parabolic trough–orc cogeneration plant for a commercial center

This paper performs technical, economic and environmental feasibility analyses of two different solar cogeneration plants, consisting of a solar system (a parabolic trough collector field coupled with thermal energy storage), an Organic Rankine Cycle (ORC), and mechanical chillers, that should cover the electrical and cooling demands of a commercial center located in Zaragoza (Spain). System A is hybridized with an auxiliary biomass boiler that complements the solar system’s thermal production, providing a constant heat supply to the ORC, which operates at full load during the operating hours of the solar system. In contrast, system B is not hybridized with biomass, so the ORC is fully driven by the solar system, operating at partial load according to the solar resource availability. Both systems are connected to the electrical grid, allowing electricity purchases and sales when needed. The design procedure involves the sizing of the equipment as well as the modelling of the hourly behavior of each system throughout the year. The physical analysis is complemented by an economic assessment, which considers investment and variable costs, as well as an estimate of the significant environmental benefits of the proposed plants. The solar plants are compared to a conventional system in which all the electrical consumption is covered with electricity purchased from the grid. The costs of the electricity produced by systems A and B are estimated at 0.2030 EUR/kWh and 0.1458 EUR/kWh, which are about 49% and 7% higher than the electricity purchase price in Spain (0.1363 EUR/kWh). These results indicate that while none of the solar plants are presently competitive with the conventional system, system B (without biomass hybridization) is actually closer to economic feasibility in the short and medium term than system A (with biomass hybridization)

Brain-derived neurotrophic factor (BDNF) and polysialylated-neural cell adhesion molecule (PSA-NCAM) in the human brainstem precerebellar nuclei from prenatal to adult age.

Occurrence and distribution of the neurotrophin brain-derived neurotrophic factor (BDNF) and polysialylated-neural cell adhesion molecule (PSA-NCAM), a neuroplasticity marker known to modulate BDNF signalling, were examined by immunohistochemistry in the human brainstem precerebellar nuclei at prenatal, perinatal and adult age. Western blot analysis performed in human brainstem showed for both molecules a single protein band compatible with the molecular weight of the dimeric form of mature BDNF and with that of PSA-NCAM. Detectability of both molecules up to 72 h post-mortem was also assessed in rat brain. In neuronal perikarya, BDNF-like immunoreactivity (LI) appeared as intracytoplasmic granules, whereas PSA-NCAM-LI appeared mostly as peripheral staining, indicative of membrane labelling; immunoreactivity to both substances also labelled nerve fibres and terminals. BDNF- and PSA-NCAM-LI occurred in the external cuneate nucleus, perihypoglossal nuclei, inferior olive complex, arcuate nucleus, lateral reticular formation, vestibular nuclei, pontine reticulotegmental and paramedian reticular nuclei, and pontine basilar nuclei. With few exceptions, for both substances the distribution pattern detected at prenatal age persisted later on, though the immunoreactivity appeared often higher in preand full-term newborns than in adult specimens. The results obtained suggest that BDNF operates in the development, maturation, maintenance and plasticity of human brainstem precerebellar neuronal systems. They also imply a multiple origin for the BDNF-LI of the human cerebellum. The codistribution of BDNF- and PSA-NCAM-LI in analyzed regions suggests that PSA-NCAM may modulate the functional interaction between BDNF and its high and low affinity receptors, an issue worth further analysis, particularly in view of the possible clinical significance of neuronal trophism in cerebellar neurodegenerative disorders.

Morphological changes induced by neuropeptide in vitro stimulation of the rat parotid gland

The effect of in vitro stimulation of rat parotid gland with the neuropeptides substance P, calcitonin gene-related peptide and galanin has been studied by microfilament fluorescence staining and in semithin sections, and compared to control incubations and in vitro stimulation with b­adrenergic and muscarinic agonists. Clear-cut aspects of massive granule exocytosis and cytoplasm vacuolation, indicative of protein and fluid secretion respectively, were obvious only after substance P stimulation, whereas treatment with galanin and calcitonin gene-related peptide produced little to no morphological changes. The results being in agreement with the outcome of other methodological approaches, these procedures appear reliable, may be effectively applied to the study of the functional regulation of secretory mechanisms, and may be particularly useful in human tissue analyses

Effect of temperature on RNA silencing of a negative-stranded RNA plant virus: Citrus psorosis virus

Citrus psorosis virus (CPsV), genus Ophiovirus, causes a bark scaling disease of citrus. CPsV virions are kinked filaments with three negative-stranded RNA molecules (vRNA) and a 48 kDa coat protein. The effect of temperature on symptom expression, virus accumulation and RNA silencing was examined in sweet orange seedlings (Citrus sinensis) graft-inoculated with three different CPsV isolates and grown in a glasshouse at 26/18°C or 32/26°C (day/night). Most plants kept in the cooler glasshouse showed a shock reaction in the first flush with shoot necrosis, and then moderate to intense chlorotic flecking and spotting in young leaves, whereas plants incubated at 32/26°C did not exhibit shoot necrosis, and young leaf symptoms were milder. Virus titre estimated by ELISA and by northern and dot blot hybridization paralleled symptom intensity, with significantly higher virus accumulation in plants incubated at 26/18°C. The amount of CPsV-derived small RNAs (CPsV-sRNAs) slightly increased at 32/26°C, with the ratio of CPsV-sRNA/vRNA being higher at 32/26°C than at 26/18°C. These results suggest that (i) CPsV infection induces RNA silencing in citrus plants, (ii) symptom intensity is associated with virus accumulation, and (iii) temperature increase enhances the RNA silencing response of citrus plants and decreases virus accumulation.Facultad de Ciencias Exacta

Effect of temperature on RNA silencing of a negative-stranded RNA plant virus: Citrus psorosis virus

Citrus psorosis virus (CPsV), genus Ophiovirus, causes a bark scaling disease of citrus. CPsV virions are kinked filaments with three negative-stranded RNA molecules (vRNA) and a 48 kDa coat protein. The effect of temperature on symptom expression, virus accumulation and RNA silencing was examined in sweet orange seedlings (Citrus sinensis) graft-inoculated with three different CPsV isolates and grown in a glasshouse at 26/18°C or 32/26°C (day/night). Most plants kept in the cooler glasshouse showed a shock reaction in the first flush with shoot necrosis, and then moderate to intense chlorotic flecking and spotting in young leaves, whereas plants incubated at 32/26°C did not exhibit shoot necrosis, and young leaf symptoms were milder. Virus titre estimated by ELISA and by northern and dot blot hybridization paralleled symptom intensity, with significantly higher virus accumulation in plants incubated at 26/18°C. The amount of CPsV-derived small RNAs (CPsV-sRNAs) slightly increased at 32/26°C, with the ratio of CPsV-sRNA/vRNA being higher at 32/26°C than at 26/18°C. These results suggest that (i) CPsV infection induces RNA silencing in citrus plants, (ii) symptom intensity is associated with virus accumulation, and (iii) temperature increase enhances the RNA silencing response of citrus plants and decreases virus accumulation.Facultad de Ciencias Exacta

The human nucleus cuneatus contains discrete territories that share neurochemical features with the relay nuclei for nociceptive information

Traditionally, the spinal dorsal column and the gracile (GN) and cuneate (CN) nuclei are believed to be involved in somatic tactile and proprioceptive perceptions. However, more recent clinical and experimental studies show that this system is also involved in the neurotransmission of visceral nociceptive stimuli (Willis et al., Proc. Natl. Acad. Sci. USA 96, 7675, 1999; Pale?ek J., Physiol. Res. 53, S125, 2004). Early studies in our laboratory (Del Fiacco et al., Brain Res. 264, 142, 1983; Neuroscience, 12, 591, 1984) showed that, at variance with that of laboratory animals, the human CN contains discrete subregions that are strongly immunoreactive to substance P, a neuropeptide classically involved in pain transmission. Here we provide further information on the chemical neuroanatomy of the human dorsal column nuclei and show that the substance P-immunoreactive subregions of the CN retain the neurochemical features of the protopathic relay nuclei. Tissue distribution of a number of neuropeptides, trophic factors and neuroplasticity-associated proteins was analyzed by immunohistochemistry in postmortem specimens of medulla oblongata from subjects aged 21 gestation weeks to 78 years, with no signs of neuropathology. Immunoreactivity to neuropeptides calcitonin gene-related peptide, leucine- and methionine-enkephalin, somatostatin, galanin, and peptide histidine-isoleucine, to trophins of the Neurotrophin and glial-derived neurotrophic factor families and related receptors, and to the neuroplasticity-associated proteins growth-associated protein-43 and polysialylated-neural cell adhesion molecule labels neuronal elements in restricted areas of the cuneate nucleus, located along its dorsal edge or embedded in the white matter of the cuneate fasciculus. Multiple immunolabelling shows that, with respect to one another, the examined substances are distributed in these regions as in the superficial layers of the spinal dorsal horn and trigeminal subnucleus caudalis. By contrast, the immunoreactivity in the GN is usually sparse and not gathered in definite subregions. The results show that, at variance with that of laboratory mammals, including primates, the human CN contains clear-cut subregions with neurochemical features reminiscent of those present in the relay nuclei for protopathic and pain perception. Moreover, the peculiar localization of the examined substances suggests that the superficial layers of those regions may constitute a “gelatinous subnucleus”. The origin as well as the functional involvement of such innervation remains to be elucidated