Liouville Vortex And φ4\varphi^{4} Kink Solutions Of The Seiberg--Witten Equations

The Seiberg--Witten equations, when dimensionally reduced to \bf R^{2}\mit, naturally yield the Liouville equation, whose solutions are parametrized by an arbitrary analytic function $g(z)$. The magnetic flux $\Phi$ is the integral of a singular Kaehler form involving $g(z)$; for an appropriate choice of $g(z)$ , $N$ coaxial or separated vortex configurations with $\Phi=\frac{2\pi N}{e}$ are obtained when the integral is regularized. The regularized connection in the \bf R^{1}\mit case coincides with the kink solution of $\varphi^{4}$ theory.Comment: 14 pages, Late

Does the Gursey-Tze Solution Represent a Monopole Condensate?

We recast the quaternionic Gursey-Tze solution, which is a fourfold quasi-periodic self-dual Yang-Mills field with a unit instanton number per Euclidean spacetime cell, into an ordinary coordinate formulation. After performing the sum in the Euclidean time direction, we use an observation by Rossi which suggests the solution represents an arrangement with a BPS monopole per space lattice cell. This may provide a concrete realization of a monopole condensate in pure Yang-Mills theory.Comment: 12 pages, Latex

A Quasiperiodic Gibbons--Hawking Metric and Spacetime Foam

We present a quasiperiodic self-dual metric of the Gibbons--Hawking type with one gravitational instanton per spacetime cell. The solution, based on an adaptation of Weierstrassian $\zeta$ and $\sigma$ functions to three dimensions, conforms to a definition of spacetime foam given by Hawking.Comment: 14 pages, Late

The impact of ESDP on EU-NATO relations

Yılmaz, Serdar (Arel Author)It could be argued that the end of the Cold War had given the EU the opportunity to forge itself as the security agent in Europe even though by the mid-1990s the atmosphere as well as the situation had changed. NATO was remerged and took the initiative to develop the defense policy. As Sjursen (1998: 95) states that the notion of a European Security and Defense Policy (ESDP) was not coined at the end of the Cold War, it was come into being with the breakdown of bipolarity in Europe. However, there are a few questions to be illuminated such as how can ESDP be defined? Is it all about creating federal Europe with its own proper and strong military power? or getting attached to the back of NATO or USA to defend the Union for external threats? In this chapter the effects of the emergence of the ESDP on NATO-EU Relations will be focused by touching upon the influence of the USA and some EU member states on this process. The theory of realism is taken into consideration to understand the main motivation of the emergence of ESDP and the essence of ESDP-NATO relations

The effect of the nitric oxide synthesis inhibitor L-NAME on amitriptyline-induced hypotension in rats

Objective: Hypotension induced by tricyclic antidepressants is multifactorial. Previous animal experiments suggest a contribution from nitric oxide production. Our study aimed to evaluate the role of nitric oxide in amitriptyline-induced hypotension using N-nitro-L-arginine methyl ester, a nitric oxide synthesis inhibitor, and 3-morpholino sydnonimine, a nitric oxide donor, in anesthetized rats. Methods: Amitriptyline intoxication was induced by the continuous infusion of amitriptyline 0.625 mg/kg/min throughout the experiment in anesthetized rats. Fifteen and 25 minutes after amitriptyline infusion began, two bolus doses of 10 mg/kg of N-nitro-L-arginine methyl ester (n = 8) or an equivalent volume of 5% dextrose solution (n = 8) was administered to each rat (Protocol 1). To investigate whether the effect of N-nitro-L-arginine methyl ester on blood pressure is counteracted by 3-morpholino sydnonimine, after the same protocol of amitriptyline infusion and 5 minutes after an N-nitro-L-arginine methyl ester bolus, a bolus of 3000 nmol/kg of 3-morpholino sydnonimine was administered (n = 8) to each rat (Protocol 2). To investigate the effect of N-nitro-L-arginine methyl ester on 3-morpholino sydnonimine induced hypotension, a group of rats received a continuous infusion of 0.54 mg/kg/h of 3-morpholino sydnonimine until 50% reduction was observed in mean arterial blood pressure followed by a bolus dose of 10 mg/kg of N-nitro-L-arginine methyl ester (n = 6) or 5% dextrose solution (n = 6) (Protocol 3). Outcome measures included mean arterial blood pressure, heart rate, and QRS duration in electrocardiogram. Student's t test and survival analysis were used for selected comparisons. Results: For all parameters, the treatment groups were similar at baseline and at postamitriptyline periods before therapy was rendered. Amitriptyline infusion significantly reduced mean arterial blood pressure by 50.8 +/- 2.2% and prolonged QRS by 23.9 +/-7.2% after 15 minutes. lit Protocol 1, N-nitro-L-arginine methyl ester significantly increased mean arterial blood pressure compared to dextrose-treated control animals within 30 minutes (77.9 +/- 8.5% vs. 49.7 +/- 5.0% mmHg, p < 0.01, 95% CI 57.1-98.7%). QRS duration progressively increased during the amitriptyline infusion; however, there leas no significant difference in QRS width between N-nitro-L-arginine methyl ester and control groups at any time point. N-nitro-L-arginine methyl ester increased survival time compared to controls (33.4 +/- 4.1 vs. 19.9 +/- 2.7 minutes, p < 0.01, 95% CI 25.4-41.3) but did not affect mortality. In Protocol 2 of continuous infusion of amitriptyline, 3-morpholino sydnonimine counteracted the N-nitro-L-arginine methyl ester-induced increase in mean arterial blood pressure. In both protocols, heart rate decreased significantly during amitriptyline infusion but there was no difference between treatment and control groups. In Protocol 3, N-nitro-L-arginine methyl ester bolus reversed 3-morpholino sydnonimine-induced hypotension compared to dextrose bolus. (83.8 +/- 5.7% vs. 54.6 +/- 4.8%, p < 0.01, 95% CI 69.2-98.4). Conclusion: N-nitro-L-arginine methyl ester is found to be effective in temporarily improving hypotension and prolonging survival tune but does not affect overall mortality. Because this effect was antagonised by 3-morpholino sydnonimine, nitric oxide production appears to contribute to the pathophysiology of amtriptyline-induced hypotension

Plasma Methylphenidate Levels in Youths With Attention Deficit Hyperactivity Disorder Treated With OROS Formulation

Background: There are limited studies investigating the relationship between oral release osmotic system-methylphenidate (OROSMPH) doses and plasma methylphenidate (MPH) concentrations in children and adolescents. The aim of this study was to investigate the relationship between the doses of OROS-MPH and the plasma levels of the drug. We also examined the effects of the other drugs including aripiprazole, risperidone, fluoxetine, and sertraline on the levels of the MPH in the plasma