Does the location of placement of meniscal sutures have a clinical effect in the all-inside repair of meniscocapsular tears?

Abstract Background Meniscocapsular separation (MCS) is a lesion of the area which is attached from the peripheral section of the meniscus to the capsule and is seen less often than other meniscus injuries. The aim of this study was to investigate which of the different side applications of all-inside MCS repair of the meniscus was better in respect of clinical and functional results. Methods In this retrospective study, 53 patients with MCS pattern in their knee joints were treated with arthroscopic meniscus repair made with the all-inside method. The patients were separated into three groups according to the surface from which the fixation was applied: group 1, from the femoral joint surface of the meniscus (n = 17), group 2, from the tibial joint surface of the meniscus (n = 21) and group 3, from the femoral and tibial joint surfaces of the meniscus (n = 15). The participants were assessed using the subjective International Knee Documentation Committee Scoring (IKDC), Lysholm Knee Scale, Tegner Activity Level Scale, Barrett criteria and Kellgren–Lawrence classification after a 45 ± 12.1 months (range, 24–70 months) follow-up. Results Postoperatively, all the groups exhibited significantly increased subjective IKDC score, Lysholm score and Tegner activity score compared with their preoperative results (p < 0.001). At 6 months postoperatively, a statistically significant difference was determined between the groups in respect of the subjective IKDC score, Tegner activity score and Lysholm score with group 2 showing better results than the other groups (p < 0.001). At the final follow-up examination, no statistically significant difference was determined between the groups in respect of the subjective IKDC score, Tegner activity score or Lysholm score. A statistically significantly lower level of pulling and stress sensation was determined in group 2 (p < 0.001). Conclusions MCS repair made with the all-inside method is successful clinically and functionally and in respect of MRI findings. In addition, it was seen that the fixation method applied from the tibial surface of the meniscus does not disturb the anatomic position of the meniscus in MCS repair. The tibial joint surface is the most appropriate area for suturation in all-inside repair of MCS. Level of evidence Level IV

Primary and Collagen Supported Scaffold Healing in Rabbit Horizontal Meniscus Ripped Models

Bu çalışmanın amacı, tavşan modelinde horizontal menisküs yırtıklarının onarımında kollajen skafold kullanımı sonrası menisküsün iyileşme potansiyelini araştırmak ve skafold ile tamirin primer tamirden daha üstün olup olmadığını göstermektir. Ağırlıkları 2.5-3 kg arasında değişen olgun 21 adet New Zealand White cinsi erkek tavşanlar her grupta 7 hayvan olacak şekilde 3 eşit gruba ayrıldı. Medial menisküs anterior boynuzdan orta kısmına kadar horizontal yırtık modeli yapıldı. Çalışma protokolüne uygun olarak, Grup 1 (n=7); kontrol grubu sadece horizontal menisküs yırtığı olan tavşanlardan oluşturuldu. Grup 2 (n=7); horizontal menisküs yırtığa primer tamir yapılırken, Grup 3; horizontal menisküs yırtığa kollajen skafold ile tamir yapılanlar idi. Tüm deney hayvanları 12. haftanın sonunda sakrifiye edildi. Medial menisküsün 1/3 anterior alanı ölçüldü. Dokuların histolojik analizi, üç bileşenden oluşan Ishida skoru ile gerçekleştirildi. Grup I'deki menisküsün yüzey alanı grup II’den (p<0.008) ve grup III'ten (p<0.002) anlamlı olarak daha düşüktü. Grup III’deki dokunun kalitesi İshida puanına göre değerlendirildiğinde diğer gruplardan anlamlı olarak daha yüksekti (p<0.001). Horizontal menisküs yırtıkları gibi avasküler bölgelerindeki yırtıklarda skafold ve benzeri materyaller ile daha iyi iyileşme ve normal anatomik dokuya yakın işlev ve fonksiyonda menisküs elde edilebilir.The aim of this study is to investigate the potential for improvement of the collagen scaffold in the repair of horizontal meniscus tears in the rabbit model. Mature 21 New Zealand white male rabbits weighing 2.5-3 kg were divided into 3 equal groups, with 7 animals in each group. The medial meniscus was anteriorly horizontal torn from the horn to the middle. In accordance with the study protocol, Group 1 (n=7); only the horizontal meniscus was tilted in the control group. Group 2 (n=7); horizontal meniscus rupture primer repair. Group 3; horizontal meniscus were repaired with a colloidal scaffold. All experimental animals were sacrificed at the end of the 12th week. 1/3 anterior area of medial meniscus was measured. Histological analysis of the tissues was performed with Ishida score consisting of three components. Surface area of meniscus in group I was significantly lower than group II (p<0.008) and group III (p<0.002). The quality of the group III was significantly higher than the other groups (p<0.001). In the tears of the avascular region, such as the horizontal meniscus tears, scaffolds and similar materials can provide better healing and meniscal function and function close to normal anatomic tissu

Effects of supplemental effective microorganism on performance, some histological and blood parameters of broiler

Feed additives including antibiotics have been widely used in poultry industry for several decades. The ban of antibiotics use as feed additives has led to investigations for alternatives to antibiotics. EM products originated in Japan after being discovered by Dr. Teruo Higa, a professor of horticulture. EM products have been on the market since 1983 and is now produced in over 156 countries. EM is a mixture of groups of anaerobic and aerobic beneficial microorganisms (lactic acid bacteria, photosynthetic bacteria, yeasts). Studies have already shown that the use of EM could improve growth parameters (feed intake, weight gain, feed conversion ratio) and/or gut histology and microbiology in broilers (Esatu ve ark., 2011, 2012; Simeamelak ve ark., 2012; Wondmeneh ve ark., 2011). However, there is still lack of information regarding the efficacy and beneficial effects of EM in broiler chicks. Sokol et al. (2009) showed also that supplemental EM increased cholesterol, albümin and LDH activity but there was no effect on the body weight gain. Safalaoh and Smith (2001) suggest that the effectiveness of supplemental EM decreased serum cholesterol content of broilers, although Safalaoh (2006) were unable to confirm this observation statistically. The present study was conducted to investigate the effects of effective microorganism (EM) supplied by drinking water and/or spraying onto poultry litter on performance, intestine histology and serum ALT, AST, glucose, cholesterol and triglycerides concentration of broiler chicks