COVID-19 and the targets of SDG 8: reflections on Brazilian scenario

Purpose: This paper aims to present reflections on the COVID-19 pandemic impacts in the search for the targets of Sustainable Development Goal 8 (SDG 8) disseminated by the United Nations. These reflections are made considering the Brazilian scenario. Design/methodology/approach: As this paper is a viewpoint, several information presented here are based on authors’ opinion. However, to enhance the information basis and present examples, a bibliographic research was also conducted. Findings: Analyzing the targets of SDG 8 and the probable crisis in the Brazilian economy as a consequence of the pandemic, the authors believe that this crisis will impact the achievement of these targets. Practical implications: The reflections presented here can contribute with the debates about the search for decent work in Brazil. It is worth to remember that the development of actions aligned with SDG 8 targets generates more than only economic gains, as these contribute for building a more just, egalitarian and inclusive society. Originality/value: This viewpoint calls attention to issues that demand urgent public policies; otherwise, these issues can generate losses to an entire generation of Brazilians

Analysis of sustainability insertion in materials selection courses of engineering undergraduate programmes

Purpose: This study aims to analyse how the materials selection courses of engineering undergraduate programmes can be better aligned with the United Nations Sustainable Development Goals (SDGs). Design/methodology/approach: Initially, a content analysis was performed in 39 materials selection course descriptions from 40 engineering undergraduate programmes of Brazilian higher education institutions, and subsequently, Delphi method procedures were conducted with professors that teach or have taught the course and are knowledgeable in the subject of sustainability. Findings: Considering the analysed course descriptions, it was shown that most of the materials selection courses do not consider or present little emphasis on sustainability aspects. Regarding the Delphi method, eight items were evidenced to consider sustainability aspects in the analysed courses. Originality/value: This study contributes to the debates about sustainability insertion in engineering undergraduate programmes. More specifically, the findings presented consolidated information that professors and coordinators can use to align materials selection courses with the SDGs better

Towards the SDGs for gender equality and decent work: investigating major challenges faced by Brazilian women in STEM careers with international experience

This paper aims to understand the main difficulties faced by women throughout their careers in Brazil and abroad. Based on the information gathered from these experiences, it seeks to advance the discussion on women's participation in STEM focusing on SDG 5 (gender equality) and SDG 8 (decent work). The main difficulties experienced by women in STEM as discussed in the academic literature were mapped. This provided input to develop a questionnaire containing qualitative and quantitative questions used to conduct interviews with women working in STEM. The sample consisted of highly qualified professionals working in high positions in the hierarchies of multinational companies in the STEM field with experience both in Brazil and abroad. The data collected was analyzed using a mixed-methods approach, including content analysis for qualitative questions and the Grey Relational Analysis for quantitative questions. The results revealed that the lack of flexible work systems, the scarcity of gender-sensitive organizational policies and labor policies, and the prevalence of traditional cultural models are some of the main difficulties faced both in Brazil and abroad by the women interviewed. The need to discuss issues of gender equality and decent work in the early stages of education is important for increasing women’s participation in STEM, which is a critical factor in the development of inclusive organizations and in fully achieving the sustainable development of society. This paper presents a unique perspective of the perceived difficulties faced by executive women who worked in Brazil and in different countries (i.e., Canada, Denmark, France, Germany, Switzerland and the United States). Gender equality in organizations is highly context-dependent, and cross-cultural analysis generates relevant insights to face the challenges and advance the discussion on women’s participation in STEM

Genetic Evidence for Inhibition of Bacterial Division Protein FtsZ by Berberine

Background: Berberine is a plant alkaloid that is widely used as an anti-infective in traditional medicine. Escherichia coli exposed to berberine form filaments, suggesting an antibacterial mechanism that involves inhibition of cell division. Berberine is a DNA ligand and may induce filamentation through induction of the SOS response. Also, there is biochemical evidence for berberine inhibition of the cell division protein FtsZ. Here we aimed to assess possible berberine mechanism(s) of action in growing bacteria using genetics tools. Methodology/Principal Findings: First, we tested whether berberine inhibits bacterial growth through DNA damage and induction of the SOS response. The SOS response induced by berberine was much lower compared to that induced by mitomycin C in an SOS response reporter strain. Also, cell filamentation was observed in an SOS-negative E. coli strain. To test whether berberine inhibits FtsZ, we assessed its effects on formation of the cell division Z-rings, and observed a dramatic reduction in Z-rings in the presence of berberine. We next used two different strategies for RNA silencing of ftsZ and both resulted in sensitisation of bacteria to berberine, visible as a drop in the Minimum Inhibitory Concentration (MIC). Furthermore, Fractional Inhibitory Concentration Indices (FICIs) showed a high level of synergy between ftsZ silencing and berberine treatment (FICI values of 0.23 and 0.25 for peptide nucleic acid- and expressed antisense RNA-based silencing of ftsZ, respectively). Finally, over-expression of ftsZ led to a mild rescue effect in berberine-treated cells

Adaptation of Scheffersomyces stipitis to hardwood spent sulfite liquor by evolutionary engineering

Hardwood spent sulfite liquor (HSSL) is a by-product of acid sulfite pulping process that is rich in xylose, a monosaccharide that can be fermented to ethanol by Scheffersomyces stipitis. However, HSSL also contains acetic acid and lignosulfonates that are inhibitory compounds of yeast growth. The main objective of this study was the use of an evolutionary engineering strategy to obtain variants of S. stipitis with increased tolerance to HSSL inhibitors while maintaining the ability to ferment xylose to ethanol

Logistics 4.0 in brazil: Critical analysis and relationships with sdg 9 targets

The logistics sector is characterised as an important pillar of the Brazilian economy, significant regarding revenue and job creation. This study aims to critically analyse the logistical operations developed by Brazilian companies in the context of Logistics 4.0 and to structure a SWOT (strengths, weaknesses, opportunities and threats) matrix from the information gathered. In addition, relationships were established between the structured SWOT matrix and the targets of Sustainable Development Goal 9 (SDG 9). The methodological approach taken by the study consisted of semi-structured interviews with ten experts and data were analysed through content analysis. Once structured the SWOT matrix, the results were related with the targets of the SDG 9. The study presented the weaknesses and threats stand out in relation to the strengths and opportunities. When compared with the targets of SDG 9, it is possible to observe that many weaknesses are related to infrastructure and innovation. The main contributions of the study are the following: it is one of the few studies which holistically examined the sector in Brazil from a Logistics 4.0 perspective and the study points out some essential needs which should be addressed. The information presented here can broaden the debates on this topic and assist companies and government in the transition to digital transformation