The Proper Perineal Prostatectomy Incision.

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First-principles investigation of the magnetoelectric properties of Ba7Mn4O15

Type-II multiferroics, in which the magnetic order breaks inversion symmetry, are appealing for both fundamental and applied research due their intrinsic coupling between magnetic and electrical orders. Using first-principles calculations we study the ground state magnetic behaviour of Ba7Mn4O15 which has been classified as a type-II multiferroic in recent experiments. Our constrained moment calculations with the proposed experimental magnetic structure shows the spontaneous emergence of a polar mode giving rise to an electrical polarisation comparable to other known type-II multiferroics. When the constraints on the magnetic moments are removed, the spins self-consistently relax into a canted antiferromagnetic ground state configuration where two magnetic modes transforming as distinct irreducible representations coexist. While the dominant magnetic mode matches well with the previous experimental observations, the second mode is found to possess a different character resulting in a non-polar ground state. Interestingly, the non-polar magnetic ground state exhibits a significantly strong linear magnetoelectric coupling comparable to the well-known multiferroic BiFeO3, suggesting strategies to design new linear magnetoelectrics

q-Space Imaging Yields a Higher Effect Gradient to Assess Cellularity than Conventional Diffusion-weighted Imaging Methods at 3.0 T : A Pilot Study with Freshly Excised Whole-Breast Tumors

N.S. supported by Biotechnology and Biological Sciences Research Council (1654748, BB/M010996/1). Study supported by the National Health Service Grampian Endowment Fund (15/1/052).Peer reviewedPublisher PD

Peri-tumoural spatial distribution of lipid composition and tubule formation in breast cancer

[Acknowledgements:] The authors would like to thank Dr. Matthew Clemence (Philips Healthcare Clinical Science, UK) for clinical scientist support, Ms Bolanle Brikinns for patient recruitment support and Ms Dawn Younie for logistic support. [Funding:] This project was funded by NHS Grampian Endowment Research Fund (15/1/052). Sai Man Cheung’s PhD study was jointly supported by Elphinstone scholarship, Roland Sutton Academic Trust and John Mallard scholarship and is currently funded by Cancer Research UK (C68628/A28312). Nicholas Senn’s PhD study was supported by BBSRC EASTBIO scholarship (1654748). The funding sources were not involved in the study design, in the collection, analysis and interpretation of data, in the writing of the report nor in the decision to submit the article for publicationPeer reviewedPublisher PD

Pressure-dependent phase transitions in hybrid improper ferroelectric Ruddlesden-Popper oxides

The temperature-dependent phase transitions in Ruddlesden-Popper oxides with perovskite bilayers have been under increased scrutiny in recent years due to the so-called hybrid improper ferroelectricity that some chemical compositions exhibit. However, little is currently understood about the hydrostatic pressure dependence of these phase transitions. Herein we present the results of a combined high-pressure powder synchrotron x-ray diffraction experiment and abinitio study on the bilayered Ruddlesden-Popper phases Ca3Mn2O7 and Ca3Ti2O7. In both compounds we observe a first-order phase transition, that in combination with our density functional theory calculations, we can confidently assign as being between polar A21am and nonpolar Acaa structures. Interestingly, we show that while the application of pressure ultimately favors a nonpolar phase, as is commonly observed for proper ferroelectrics, regions of response exist where pressure actually acts to increase the polar mode amplitudes. The reason for this can be untangled by considering the varied response of octahedral tilts and rotations to hydrostatic pressure and their trilinear coupling with the polar instability

A novel class of 1H-MRI Contrast Agents based on the relaxation enhancement induced on water protons by 14N imidazole moieties

Acknowledgements: This project has received funding from the European Union Horizon 2020 research and innovation programme under grant agreement No 668119 (project “IDentIFY”) and from the ATTRACT project funded by the EC under Grant Agreement No.777222. This work was performed in the frame of the COST Action AC15209 (EURELAX). The Italian Ministry for Educationand Research (MIUR) is gratefully acknowledged for yearly FOE funding to the Euro-BioImaging Multi-Modal Molecular Imaging Italian Node (MMMI).Peer reviewedPostprin

Phased-array combination of 2D MRS for lipid composition quantification in patients with breast cancer

Acknowledgements: The author would like to thank Dr Matthew Clemence (Philips Healthcare Clinical Science, UK) for clinical scientist support, Ms Bolanle Brikinns, Ms Louisa Pirie, Ms Linda Lett, and Ms Kate Shaw, for patient recruitment support, Ms Dawn Younie for logistic support, Mr Roger Bourne and Ms Mairi Fuller for providing access to the patients as well as Mrs Beverly MacLennan, Mrs Nicola Crouch, Mr Mike Hendry, and Ms Laura Reid for radiographer support. Funding: This project was funded by Friends of Aberdeen and North Centre for Haematology, Oncology and Radiotherapy (ANCHOR), Tenovus Scotland, and NHS Grampian Endowment. Vasiliki Mallikourti’s PhD study is supported by The Princess Royal Tenovus Scotland Medical Research Scholarship.Peer reviewedPublisher PD

Monitoring tissue implants by field-cycling H-1-MRI via the detection of changes in the N-14-quadrupolar-peak from imidazole moieties incorporated in a "smart" scaffold material

Acknowledgements This work was performed in the frame of the COST Action AC15209 (EURELAX). The authors acknowledge the Italian Ministry of Research for FOE contribution to the EuroBioImaging MultiModal Molecular Imaging Italian Node (www.mmmi.unito.it). This project has received funding from the European Union Horizon 2020 research and innovation program under grant agreement No 668119 (project “IDentIFY”) and from the ATTRACT project funded by the EC under Grant Agreement No. 777222.Peer reviewedPostprin

Metabolic and structural skeletal muscle health in systemic lupus erythematosus related fatigue : a multi-modal magnetic resonance imaging study

Funding: This work was supported by Lupus UK Acknowledgements. Special thanks to the patient community who participated in this research effort.Peer reviewedPostprin