350 research outputs found
Simulation of lightning surges on tower transmission using PSCAD/EMTDC: a comparative study
This paper describes the analytical and the experimental responses of the surges strike on the transmission line towers. A new method of calculating transmission tower surge response has been proposed. It has been found that the tower surge response calculated by the proposed method has a close agreement with the measured tower surge response obtained from scale model and field tests. Without the use of simulation program, this topic might be difficult to understand. PSCAD/EMTDC has been selected as the software used to generate the appropriate data needed to graphically demonstrate this phenomenon
Isolation, screening and identification of amylase and catalase producing bacterial strains from marine sediments
Marine sediments are valuable source of industrially useful enzymes. Here, we attempted isolation, screening and identification of bacterial strains from marine sediments which produce industrially important enzymes amylase and catalase. Marine sediment samples were collected and cultured on zobell marine agar medium. After incubation, the isolates that showed amylase and catalase activity were selected for the assay. The strains AM01 and Ca07 showed the highest amylase and catalase activity, respectively. The selected strains were further sequenced for identification. Morphological studies indicated that the isolates were Gram -ve, rod shaped and non-motile organism. The phenotypic characterization and 16S rRNA of the strains AM01 and Ca07 revealed them to be Klebsiella pneumoniae and K. quasipneumoniae, respectivel
Isolation, screening and identification of amylase and catalase producing bacterial strains from marine sediments
853-860Marine sediments are valuable source of industrially useful enzymes. Here, we attempted isolation, screening and identification of bacterial strains from marine sediments which produce industrially important enzymes amylase and catalase. Marine sediment samples were collected and cultured on zobell marine agar medium. After incubation, the isolates that showed amylase and catalase activity were selected for the assay. The strains AM01 and Ca07 showed the highest amylase and catalase activity, respectively. The selected strains were further sequenced for identification. Morphological studies indicated that the isolates were Gram -ve, rod shaped and non-motile organism. The phenotypic characterization and 16S rRNA of the strains AM01 and Ca07 revealed them to be Klebsiella pneumoniae and K. quasipneumoniae, respectively
Green Synthesis of High Temperature Stable Anatase Titanium Dioxide Nanoparticles Using Gum Kondagogu: Characterization and Solar Driven Photocatalytic Degradation of Organic Dye
The present study reports a green and sustainable method for the synthesis of titanium dioxide (TiO2) nanoparticles (NPs) from titanium oxysulfate solution using Kondagogu gum (Cochlospermum gossypium), a carbohydrate polymer, as the NPs formation agent. The synthesized TiO2 NPs were categorized by techniques such as X-Ray Diffraction (XRD), Fourier transform infrared (FTIR) spectroscopy analysis, Raman spectroscopy, scanning electron microscope- Energy-dispersive X-ray spectroscopy (SEM-EDX), Transmission electron microscopy (TEM), High-resolution transmission electron microscopy (HR-TEM), UV-visible spectroscopy, Brunauer-Emmett-Teller (BET) surface area and particle size analysis. Additionally, the photocatalytic actions of TiO2 NPs were assessed with regard to their ability to degrade an organic dye (methylene blue) from aqueous solution in the presence of solar light. Various parameters affecting the photocatalytic activity of the TiO2 NPs were examined, including catalyst loading, reaction time, pH value and calcination temperature of the aforementioned particles. This green synthesis method involving TiO2 NPs explores the advantages of inexpensive and non-toxic precursors, the TiO2 NPs themselves exhibiting excellent photocatalytic activity against dye molecules
A dosimetric analysis of respiration-gated radiotherapy in patients with stage III lung cancer
BACKGROUND: Respiration-gated radiotherapy can permit the irradiation of smaller target volumes. 4DCT scans performed for routine treatment were retrospectively analyzed to establish the benefits of gating in stage III non-small cell lung cancer (NSCLC). MATERIALS AND METHODS: Gross tumor volumes (GTVs) were contoured in all 10 respiratory phases of a 4DCT scan in 15 patients with stage III NSCLC. Treatment planning was performed using different planning target volumes (PTVs), namely: (i) PTV(routine), derived from a single GTV plus 'conventional' margins; (ii) PTV(all phases )incorporating all 3D mobility captured by the 4DCT; (iii) PTV(gating), incorporating residual 3D mobility in 3–4 phases at end-expiration. Mixed effect models were constructed in order to estimate the reductions in risk of lung toxicity for the different PTVs. RESULTS: Individual GTVs ranged from 41.5 – 235.0 cm(3). With patient-specific mobility data (PTV(all phases)), smaller PTVs were derived than when 'standard' conventional margins were used (p < 0.001). The average residual 3D tumor mobility within the gating window was 4.0 ± 3.5 mm, which was 5.5 mm less than non-gated tumor mobility (p < 0.001). The reductions in mean lung dose were 9.7% and 4.9%, respectively, for PTV(all phases )versus PTV(routine), and PTV(gating )versus PTV(all phases). The corresponding reductions in V(20 )were 9.8% and 7.0%, respectively. Dosimetric gains were smaller for primary tumors of the upper lobe versus other locations (p = 0.02). Respiratory gating also reduced the risks of radiation-induced esophagitis. CONCLUSION: Respiration-gated radiotherapy can reduce the risk of pulmonary toxicity but the benefits are particularly evident for tumors of the middle and lower lobes
P3-177: Essential role for intensity-modulated radiotherapy (IMRT) in post-pneumonectomy mediastinal radiotherapy for stage III-N2 non-small cell lung cancer
Comparison of MR‐guided radiotherapy accumulated doses for central lung tumors with non‐adaptive and online adaptive proton therapy
Background
Stereotactic body radiation therapy (SBRT) of central lung tumors with photon or proton therapy has a risk of increased toxicity. Treatment planning studies comparing accumulated doses for state-of-the-art treatment techniques, such as MR-guided radiotherapy (MRgRT) and intensity modulated proton therapy (IMPT), are currently lacking.
Purpose
We conducted a comparison of accumulated doses for MRgRT, robustly optimized non-adaptive IMPT, and online adaptive IMPT for central lung tumors. A special focus was set on analyzing the accumulated doses to the bronchial tree, a parameter linked to high-grade toxicities.
Methods
Data of 18 early-stage central lung tumor patients, treated at a 0.35 T MR-linac in eight or five fractions, were analyzed. Three gated treatment scenarios were compared: (S1) online adaptive MRgRT, (S2) non-adaptive IMPT, and (S3) online adaptive IMPT. The treatment plans were recalculated or reoptimized on the daily imaging data acquired during MRgRT, and accumulated over all treatment fractions. Accumulated dose-volume histogram (DVH) parameters of the gross tumor volume (GTV), lung, heart, and organs-at-risk (OARs) within 2 cm of the planning target volume (PTV) were extracted for each scenario and compared in Wilcoxon signed-rank tests between S1 & S2, and S1 & S3.
Results
The accumulated GTV D98% was above the prescribed dose for all patients and scenarios. Significant reductions (p < 0.05) of the mean ipsilateral lung dose (S2: –8%; S3: –23%) and mean heart dose (S2: –79%; S3: –83%) were observed for both proton scenarios compared to S1. The bronchial tree D0.1cc was significantly lower for S3 (S1: 48.1 Gy; S3: 39.2 Gy; p = 0.005), but not significantly different for S2 (S2: 45.0 Gy; p = 0.094), compared to S1. The D0.1cc for S2 and S3 compared to S1 was significantly (p < 0.05) smaller for OARs within 1–2 cm of the PTV (S1: 30.2 Gy; S2: 24.6 Gy; S3: 23.1 Gy), but not significantly different for OARs within 1 cm of the PTV.
Conclusions
A significant dose sparing potential of non-adaptive and online adaptive proton therapy compared to MRgRT for OARs in close, but not direct proximity of central lung tumors was identified. The near-maximum dose to the bronchial tree was not significantly different for MRgRT and non-adaptive IMPT. Online adaptive IMPT achieved significantly lower doses to the bronchial tree compared to MRgRT
Evaluation of onset, cessation and seasonal precipitation of the Southeast Asia rainy season in CMIP5 regional climate models and HighResMIP global climate models
Representing the rainy season of the maritime continent is a challenge for global and regional climate models. Here, we compare regional climate models (RCMs) based on the coupled model intercomparison project phase 5 (CMIP5) model generation with high-resolution global climate models with a comparable spatial resolution from the HighResMIP experiment. The onset and the total precipitation of the rainy season for both model experiments are compared against observational datasets for Southeast Asia. A realistic representation of the monsoon rainfall is essential for agriculture in Southeast Asia as a delayed onset jeopardizes the possibility of having three annual crops. In general, the coupled historical runs (Hist-1950) and the historical force atmosphere run (HighresSST) of the high-resolution model intercomparison project (HighResMIP) suite were consistently closer to the observations than the RCM of CMIP5 used in this study. We find that for the whole of Southeast Asia, the HighResMIP models simulate the onset date and the total precipitation of the rainy season over the region closer to the observations than the other model sets used in this study. High-resolution models in the HighresSST experiment showed a similar performance to their low-resolution equivalents in simulating the monsoon characteristics. The HighresSST experiment simulated the anomaly of the onset date and the total precipitation for different El Niño-southern oscillation conditions best, although the magnitude of the onset date anomaly was underestimated. © 2021 The Authors. International Journal of Climatology published by John Wiley Sons Ltd on behalf of Royal Meteorological Society
Impact of increased resolution on long-standing biases in HighResMIP-PRIMAVERA climate models
We examine the influence of increased resolution on four long-standing biases using five different climate models developed within the PRIMAVERA project. The biases are the warm eastern tropical oceans, the double Intertropical Convergence Zone (ITCZ), the warm Southern Ocean, and the cold North Atlantic. Atmosphere resolution increases from ∼100–200 to ∼25–50 km, and ocean resolution increases from (eddy-parametrized) to (eddy-present). For one model, ocean resolution also reaches ∘ (eddy-rich). The ensemble mean and individual fully coupled general circulation models and their atmosphere-only versions are compared with satellite observations and the ERA5 reanalysis over the period 1980–2014. The four studied biases appear in all the low-resolution coupled models to some extent, although the Southern Ocean warm bias is the least persistent across individual models. In the ensemble mean, increased resolution reduces the surface warm bias and the associated cloud cover and precipitation biases over the eastern tropical oceans, particularly over the tropical South Atlantic. Linked to this and to the improvement in the precipitation distribution over the western tropical Pacific, the double-ITCZ bias is also reduced with increased resolution. The Southern Ocean warm bias increases or remains unchanged at higher resolution, with small reductions in the regional cloud cover and net cloud radiative effect biases. The North Atlantic cold bias is also reduced at higher resolution, albeit at the expense of a new warm bias that emerges in the Labrador Sea related to excessive ocean deep mixing in the region, especially in the ORCA025 ocean model. Overall, the impact of increased resolution on the surface temperature biases is model-dependent in the coupled models. In the atmosphere-only models, increased resolution leads to very modest or no reduction in the studied biases. Thus, both the coupled and atmosphere-only models still show large biases in tropical precipitation and cloud cover, and in midlatitude zonal winds at higher resolutions, with little change in their global biases for temperature, precipitation, cloud cover, and net cloud radiative effect. Our analysis finds no clear reductions in the studied biases due to the increase in atmosphere resolution up to 25–50 km, in ocean resolution up to 0.25∘, or in both. Our study thus adds to evidence that further improved model physics, tuning, and even finer resolutions might be necessary
Climate model configurations of the ECMWF Integrated Forecasting System (ECMWF-IFS cycle 43r1) for HighResMIP
This paper presents atmosphere-only
and coupled climate model configurations of the European Centre for
Medium-Range Weather Forecasts Integrated Forecasting System (ECMWF-IFS) for
different combinations of ocean and atmosphere resolution. These
configurations are used to perform multi-decadal ensemble experiments
following the protocols of the High Resolution Model Intercomparison Project
(HighResMIP) and phase 6 of the Coupled Model Intercomparison Project
(CMIP6). These experiments are used to evaluate the sensitivity of major
biases in the atmosphere, ocean, and cryosphere to changes in atmosphere and
ocean resolution. All configurations successfully reproduce the observed
long-term trends in global mean surface temperature. Furthermore, following
an adjustment to account for drift in the subsurface ocean, coupled
configurations of ECMWF-IFS realistically reproduce observation-based
estimates of ocean heat content change since 1950. Climatological surface
biases in ECMWF-IFS are relatively insensitive to an increase in atmospheric
resolution from ∼ 50 to ∼ 25 km. However, increasing the horizontal
resolution of the atmosphere while maintaining the same vertical resolution
enhances the magnitude of a cold bias in the lower stratosphere. In coupled
configurations, there is a strong sensitivity to an increase in ocean model
resolution from 1 to 0.25°. However, this sensitivity to ocean
resolution takes many years to fully manifest and is less apparent in the
first year of integration. This result has implications for the ECMWF coupled
model development strategy that typically relies on the analysis of biases in
short ( < 1 year) ensemble (re)forecast data sets. The impacts of increased
ocean resolution are particularly evident in the North Atlantic and Arctic,
where they are associated with an improved Atlantic meridional overturning
circulation, increased meridional ocean heat transport, and more realistic
sea-ice cover. In the tropical Pacific, increased ocean resolution is
associated with improvements to the magnitude and asymmetry of El Niño–Southern
Oscillation (ENSO) variability and better representation of non-linear
sea surface temperature (SST)–radiation feedbacks
during warm events. However, increased ocean model resolution also increases
the magnitude of a warm bias in the Southern Ocean. Finally, there is
tentative evidence that both ocean coupling and increased atmospheric
resolution can improve teleconnections between tropical Pacific rainfall and
geopotential height anomalies in the North Atlantic.</p
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