A new surgical technique to facilitate osteochondral autograft transfer in osteochondral defects of the capitellum: A case report

A 17-year-old boy who was engaged in amateur weightlifting and body building presented with complaints of right elbow pain and limitation in elbow range of motion. Plain x-rays and magnetic resonance imaging showed an osteochondral defect in the medial third of the capitellum. At surgery, as a new technique, the lateral collateral ligament was detached from the humeral attachment to provide access to the capitellum with a clear and perpendicular exposure. Following removal of loose fragments within the joint, an osteochondral graft harvested from the lateral femoral condyle was implanted to the defect area of the capitellum. Postoperative radiologic controls showed that the defect was entirely filled by the graft with appropriate graft height. On follow-up examination at 12 months, the patient did not have any complaint about his elbow, and had no limitation of movement compared to the left elbow. Magnetic resonance imaging showed that the graft was successfully adapted to the recipient site without any sign of loosening. At final follow-up 40 months after surgery, the surface of the articular cartilage appeared normal. The range of elbow motion was preserved and the patient had no restriction in daily and sports activities. Considering technical difficulties posed by the narrow and complex structure of the elbow joint, this new technique involving detachment of the lateral collateral ligament facilitates perpendicular implantation of the graft. In our opinion, utilization of this new technique will improve functional and radiological results of osteochondral autograft transfer. © 2010 Turkish Association of Orthopaedics and Traumatology

A concise review on the use of mesenchymal stem cells in cell sheet-based tissue engineering with special emphasis on bone tissue regeneration

The integration of stem cell technology and cell sheet engineering improved the potential use of cell sheet products in regenerative medicine. This review will discuss the use of mesenchymal stem cells (MSCs) in cell sheet-based tissue engineering. Besides their adhesiveness to plastic surfaces and their extensive differentiation potential in vitro, MSCs are easily accessible, expandable in vitro with acceptable genomic stability, and few ethical issues. With all these advantages, they are extremely well suited for cell sheet-based tissue engineering. This review will focus on the use of MSC sheets in osteogenic tissue engineering. Potential application techniques with or without scaffolds and/or grafts will be discussed. Finally, the importance of osteogenic induction of these MSC sheets in orthopaedic applications will be demonstrated. © 2017 A. Cagdas Yorukoglu et al

Cefazolin-sodium has no adverse effect on fracture healing in an experimental rabbit model

Objectives: This study aims to investigate whether cefazolinsodium has any adverse effect on fracture healing in an experimental rabbit model. Materials and methods: The study was performed on 50 male New-Zealand white rabbits. Under general anesthesia, closed double fracture of middle one-third of the tibia-fibula of the left lower extremity of the subjects was produced by manual compression followed by closed reduction of fracture and long leg circular cast was applied. Subjects were divided randomly into five groups including 10 rabbits in each group. The first and second group were administered ciprofloxacin 50 mg/kg SC bid and cefazolin-sodium 50 mg/kg IM on the seventh day of fracture. The third group was applied a single high-dose of vitamin D (50.000 IU/kg) IM following fracture. The fourth group was applied daily vitamin E (alphatocopherol) 20 mg/kg IM for five days from one hour before the production of fracture. Control group did not receive any treatment before and after fracture. Initial and control X-ray examinations were performed immediately and four weeks after production of fracture, respectively. At the end of the fourth week, animals were sacrificed and a histological examination of the fracture site was performed. Results: Histological evaluation showed that the histological grade of the fracture healing was significantly lower in the ciprofloxacin group, while it was significantly higher in the cefazolin-sodium, vitamin D and vitamin E groups, compared to control group (p<0.005). Conclusion: Significantly improved histological grade of the fracture healing in subjects treated with cefazolin-sodium than controls suggest that it may be reasonable to choose cefazolin-sodium as an antibiotic therapy for the treatment of infection in patients with bone fractures

45 yaş ve üstü dejeneratif artrit ile birlikte menisküs lezyonu olan hastalarda artroskopik menisektominin değerlendirilmesi (fonksiyonel sonuçlar)

Bu tezin, veri tabanı üzerinden yayınlanma izni bulunmamaktadır. Yayınlanma izni olmayan tezlerin basılı kopyalarına Üniversite kütüphaneniz aracılığıyla (TÜBESS üzerinden) erişebilirsiniz.SUMMARY Between January 2001 and December 2004, in the Department of Orthopaedics and Traumatology of Pamukkale University, Faculty of Medicine, 139 patients who underwent arthroscopic meniscectomy for meniscal tear with degenerative arthritis, after 6-50 months whose functional scores were evaluated by Lysholm's scales. This study showed that arhroscopic meniscectomy were applied to the patients who had degenerative arthritis; the patients who had lower degree of degenerative arthritis, lesser body mass index and shorter duration of symptoms had more benefits and partial meniscectomy is more beneficial than the subtotal or total meniscectomy. Arthroscopic meniscectomy with low morbidity and complication rate is preferable treatment method for selected patients with degenerative arthritis and meniscal tear. Since the functions of the meniscii are very important, procedures like partial meniscectomy should be prefered in meniscal tear treatment. Key words: arthroscopy, menisectomy, meniscal tears osteoarthritis 59Pamukkale Üniversitesi Tıp Fakültesi, Ortopedi ve Travmatoloji Anabilim Dalında Ocak 2001 -Aralık 2004 tarihleri arasında dejeneratif artrit ile birlikte menisküs yırtığı nedeniyle artroskopik menisektomi uygulanan, 6- 50 ay sonra değerlendirilen 139 hastanın fonksiyonel skorları Lysholm Skalasına göre değerlendirildi. Bu çalışma ile dejeneratif artritli hastalarda uygulanan artroskopik menisektominin, dejeneratif artriti daha az derece olanlarda, vücut kitle indeksi daha az olanlarda ve semptom süresi daha kısa olanlarda daha faydalı olduğu ve parsiyel menisektominin subtotal veya total menisektomiye göre daha yararlı olduğu gösterildi. Artroskopik menisektomi, düşük morbidite ve komplikasyon oram ile dejeneratif artrit ve menisküs yırtığı olan seçilmiş hasta gruplarında tercih edilebilecek bir tedavi yöntemidir. Menisküs yırtıklarının tedavisinde, önemli fonksiyonları nedeniyle parsiyel menisektomi gibi menisküsleri korumaya yönelik girişimlerin tercih edilmesi gerektiği kanısındayız. Anahtar kelimeler: artroskopi,menisektomi, menisküs yırtığı,osteoartrit 5

Energy efficiency improvement of the heat pump by employing synthesized CuO/ZnO hybrid nanofluid

WOS:000729464600001In this experimental study, CuO/ZnO hybrid nanoparticles were synthesized by the co-precipitation method. While solid nanoparticles were synthesized, 5%, 10%, and 15% mass fractions of CuO were doped into ZnO nanoparticles. While preparing the nanofluids, sodium dodecyl benzene sulphonate (SUBS) surfactant material was used to prepare a homogeneous and hydrophobic suspension. The results of physical and chemical analyses of the synthesized nanoparticles were examined. In the experiments made with the heat pump, the coefficient of performance (COP) of the heat pump was calculated as 4.23 when deionized water was used as the working fluid. In the experiments with nanofluids using ZnO and 15% (wt./wt.) CuO/ZnO instead of deionized water, COP values of 4.31 and 4.44 were obtained, respectively