212 research outputs found

    Milestones chemical technology institute: our past and present

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    The article is devoted to the 95th anniversary of the Chemical technological Institute (CTI) of the Ural Federal University named after the first President of Russia B. N. Yeltsin (UrFU), which will be held in October 2015. Over the years Chemical technological Institute (CTI) has undergone many structure transformations in accordance with the tasks which were set before it the time and the development of our country. Currently this is a fairly large educational and research Institute, which employs more than 100 lecturers including more than 70 associate professors – candidates (PhD), 30 professors – doctors of Sciences (Hb), 3 academics and 1 corresponding member of RAS, trained more than 850 students

    Homeward Bound: How Translators Negotiate the Foreign in Travel and Tourism. An English-Russian Case Study.

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    My research addresses intercultural communication in the field of travel and the industry of tourism and the challenges faced by translators between cultures. In my thesis I explore selected texts about foreign travel in English and in Russian and their Russian and English translations (respectively) in order to show the importance of differentiating between the ways in which translators, travellers and tourists represent and contrast foreign and domestic elements. In Chapters One and Two, I explore target-oriented and source-oriented translations. My analysis suggests that target-oriented translation can be creatively combined with source-oriented translation, both on a semantic level, by translators of travel texts and on a narrative level, by those travellers who write accounts of their experiences. Thus translators of travel literature create a holistic image of a foreign culture using analogies familiar to readers of the target language. My comparisons of English-language The Lonely Planet and Rough Guides travel guides to China, Finland and Russia with their Russian translations suggest that texts targeted at different audiences can be significantly divergent in terms of content. Translators take different approaches not only in their use of target-oriented and source-oriented translations, but also in the degree of creativity and adaptation/localization which they employ. My analysis of articles from British Cereal magazine and their Russian translations, which I study in Chapter Three of my thesis, shows that creativity may be a legitimate aspect of translation strategy, or an attempt by publishers to alter the original text radically in order to make it more appealing to the target audience. In Chapter Four, I focus my analysis of online texts for tourists on CondΓ© Nast Traveller magazine and the Booking.Com website (both English and Russian versions) in order to establish why localization experts replace translators. My thesis concludes that the role of the translator in the travel industry encompasses a spectrum of linguistic and extra-linguistic tasks based on connections between foreign and domestic values, including strategies of localization and adaptation

    AKMEOLOGICHESKOJ APPROACH AS FORMING PROCESSES RESEARCH METHODOLOGY AKMEOLOGICHESKOJ POTENTIAL FUTURE MANAGER IN HIGH SCHOOL

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    In this work the illustration of use of acmeological approach is presented when training future managers in higher education institution. The essence of acmeological approach reveals and social need of its use for higher education with a support on researches of the Moscow and St. Petersburg acmeological schools is proved. Due to the realization of this approach need of reconsideration of elements of pedagogical process locates in higher education institution (the purposes, the principles, the contents, forms, methods, means, conditions and result).ΠŸΡ€Π΅Π΄ΡΡ‚Π°Π²Π»Π΅Π½Ρ‹ Ρ€Π΅Π·ΡƒΠ»ΡŒΡ‚Π°Ρ‚Ρ‹ примСнСния акмСологичСского ΠΏΠΎΠ΄Ρ…ΠΎΠ΄Π° ΠΏΡ€ΠΈ ΠΎΠ±ΡƒΡ‡Π΅Π½ΠΈΠΈ Π±ΡƒΠ΄ΡƒΡ‰ΠΈΡ… ΠΌΠ΅Π½Π΅Π΄ΠΆΠ΅Ρ€ΠΎΠ² Π² Π²ΡƒΠ·Π΅. РаскрываСтся ΡΡƒΡ‰Π½ΠΎΡΡ‚ΡŒ акмСологичСского ΠΏΠΎΠ΄Ρ…ΠΎΠ΄Π° ΠΈ доказываСтся ΡΠΎΡ†ΠΈΠ°Π»ΡŒΠ½Π°Ρ Π½Π΅ΠΎΠ±Ρ…ΠΎΠ΄ΠΈΠΌΠΎΡΡ‚ΡŒ Π΅Π³ΠΎ использования Π² Π²Ρ‹ΡΡˆΠ΅ΠΌ ΠΏΡ€ΠΎΡ„Π΅ΡΡΠΈΠΎΠ½Π°Π»ΡŒΠ½ΠΎΠΌ ΠΎΠ±Ρ€Π°Π·ΠΎΠ²Π°Π½ΠΈΠΈ, с ΠΎΠΏΠΎΡ€ΠΎΠΉ Π½Π° исслСдования Московской ΠΈ Π‘Π°Π½ΠΊΡ‚-ΠŸΠ΅Ρ‚Π΅Ρ€Π±ΡƒΡ€Π³ΡΠΊΠΎΠΉ акмСологичСских школ. Π’ связи с Ρ‚Π°ΠΊΠΈΠΌ ΠΏΡ€ΠΈΠΌΠ΅Ρ€ΠΎΠΌ Ρ€Π΅Π°Π»ΠΈΠ·Π°Ρ†ΠΈΠΈ акмСологичСского ΠΏΠΎΠ΄Ρ…ΠΎΠ΄Π° Π² Π²ΡƒΠ·Π΅ обосновываСтся Π½Π΅ΠΎΠ±Ρ…ΠΎΠ΄ΠΈΠΌΠΎΡΡ‚ΡŒ пСрСосмыслСния элСмСнтов пСдагогичСского процСсса (Ρ†Π΅Π»Π΅ΠΉ, ΠΏΡ€ΠΈΠ½Ρ†ΠΈΠΏΠΎΠ², содСрТания, Ρ„ΠΎΡ€ΠΌ, ΠΌΠ΅Ρ‚ΠΎΠ΄ΠΎΠ², срСдств, условий ΠΈ Ρ€Π΅Π·ΡƒΠ»ΡŒΡ‚Π°Ρ‚Π°)

    Nuclear BK channels regulate CREB phosphorylation in RAW264.7 macrophages

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    BACKGROUND: Macrophages are important cells of the innate immune system and contribute to a variety of physiological and pathophysiological responses. Monovalent and divalent ion channels have been studied in macrophage function, and while much research is still required, a role for these channels is beginning to emerge in macrophages. In addition to the plasma membrane, ion channels are also found in intracellular membranes including mitochondrial, lysosomal and nuclear membranes. While studying the function of plasma membrane located large conductance voltage- and calcium-activated potassium channels (BK channels) in a macrophage cell line RAW264.7, we became aware of the expression of these ion channels in other cellular locations. METHODS: Immunofluorescence and Western blot analysis were used to identify the expression of BK channels. To demonstrate a functional role for the nuclear located channel, we investigated the effect of the lipid soluble BK channel inhibitor paxilline on CREB phosphorylation. RESULTS: Treatment of resting macrophages with paxilline resulted in increased CREB phosphorylation. To confirm a role for nuclear BK channels, these experiments were repeated in isolated nuclei and similar results were found. Ca2+ and calmodulin-dependent kinases (CaMK) have been demonstrated to regulate CREB phosphorylation. Inhibition of CaMKII and CaMKIV resulted in the reversal of paxilline-induced CREB phosphorylation. CONCLUSIONS: These results suggest that nuclear BK channels regulate CREB phosphorylation in macrophages. Nuclear located ion channels may therefore be part of novel signalling pathways in macrophages and should be taken into account when studying the role of ion channels in these and other cells

    The influence of the industrial complex on the atmospheric air in the Sverdlovsk region

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    The work is dedicated to studying the level dynamics of polluting substances emissions into the atmosphere of Yekaterinburg city and the Sverdlovsk region in the period of 2012-2016. In the process of our work we found out an insignificant reduction of main indicators values such as SI, HR, and IPA to estimate the atmospheric air quality. Nevertheless, the level of the air pollution in Yekaterinburg city remained high in the stated period. We also suggested some methods to reduce enterprises emissions in the article, which will lead to improving the air quality. In the result of our work it was established that the main pollutants are suspended particles, nitrogen dioxides, phenol, and benzene. Moreover, the connection between the atmospheric air pollution degree and the Sverdlovsk region population's health was determined. Β© 2018 Institute of Physics Publishing. All rights reserved

    Documented procedure Β«Control of nonconforming productΒ» in anticipation of the re-certification of the management system of the organization

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    РСсСртификация систСма ΠΌΠ΅Π½Π΅Π΄ΠΆΠΌΠ΅Π½Ρ‚Π° ΠΎΡ€Π³Π°Π½ΠΈΠ·Π°Ρ†ΠΈΠΈ Π½Π° соотвСтствиС трСбованиям Π“ΠžΠ‘Π’ Π  ИБО 9001:2015 обязываСт ΠΎΠ±Π½ΠΎΠ²Π»ΡΡ‚ΡŒ ΠΈ Π°ΠΊΡ‚ΡƒΠ°Π»ΠΈΠ·ΠΈΡ€ΠΎΠ²Π°Ρ‚ΡŒ Π΄ΠΎΠΊΡƒΠΌΠ΅Π½Ρ‚Π°Ρ†ΠΈΡŽ БМК для Ρ€Π΅Π·ΡƒΠ»ΡŒΡ‚Π°Ρ‚ΠΈΠ²Π½ΠΎΠ³ΠΎ ΠΈ эффСктивного прохоТдСния ΠΊΠ°ΠΊ Π²Π½ΡƒΡ‚Ρ€Π΅Π½Π½Π΅Π³ΠΎ, Ρ‚Π°ΠΊ ΠΈ внСшнСго Π°ΡƒΠ΄ΠΈΡ‚Π°Recertification of the organization's management system for compliance with GOST R ISO 9001:2015 requires to update or keep current the documentation of the QMS for efficient and ef-fective flow of both internal and external audi

    Π˜Π½ΠΆΠ΅Π½Π΅Ρ€Π½ΠΎ-гСологичСскоС Ρ€Π°ΠΉΠΎΠ½ΠΈΡ€ΠΎΠ²Π°Π½ΠΈΠ΅ участка ΠΆΠ΅Π»Π΅Π·Π½ΠΎΠΉ Π΄ΠΎΡ€ΠΎΠ³ΠΈ ΠΌΠ΅Ρ‚ΠΎΠ΄ΠΎΠΌ вСроятностной ΠΎΡ†Π΅Π½ΠΊΠΈ классификационного показатСля

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    The article describes the special engineering-geological zoning method of the railway territory. Permafrost geocryological conditions of the railway geological section were analyzed. The area is characterized by sporadic discontinuous permafrost. The analysis showed that the process of flooding is widely developed at the stusy area. It will have a great impact on the design and operation of the structure. The method of probabilistic assessment was used for a reasonable zonation of the territory. In result of the study, three taxa were identified that allows defining the flooded, potentially flooded, and non-flooded areas according to their geological structure. Measures for reducing the negative impact of flooding processes are recommended.ИзлоТСна ΠΌΠ΅Ρ‚ΠΎΠ΄ΠΈΠΊΠ° ΡΠΏΠ΅Ρ†ΠΈΠ°Π»ΡŒΠ½ΠΎΠ³ΠΎ ΠΈΠ½ΠΆΠ΅Π½Π΅Ρ€Π½ΠΎ-гСологичСского районирования Ρ‚Π΅Ρ€Ρ€ΠΈΡ‚ΠΎΡ€ΠΈΠΈ ΠΆΠ΅Π»Π΅Π·Π½ΠΎΠ΄ΠΎΡ€ΠΎΠΆΠ½ΠΎΠ³ΠΎ ΠΏΡƒΡ‚ΠΈ. Для этого Π±Ρ‹Π»ΠΈ ΠΏΡ€ΠΎΠ°Π½Π°Π»ΠΈΠ·ΠΈΡ€ΠΎΠ²Π°Π½Ρ‹ гСокриологичСскиС условия участка ΠΆΠ΅Π»Π΅Π·Π½ΠΎΠΉ Π΄ΠΎΡ€ΠΎΠ³ΠΈ Β«ΠŸΠ°Π½Π³ΠΎΠ΄Ρ‹ – Новый Π£Ρ€Π΅Π½Π³ΠΎΠΉΒ», Ρ…Π°Ρ€Π°ΠΊΡ‚Π΅Ρ€ΠΈΠ·ΡƒΡŽΡ‰ΠΈΠ΅ΡΡ островным распространСниСм ΠΌΠ½ΠΎΠ³ΠΎΠ»Π΅Ρ‚Π½Π΅ΠΌΠ΅Ρ€Π·Π»Ρ‹Ρ… ΠΏΠΎΡ€ΠΎΠ΄. Анализ ΠΏΠΎΠΊΠ°Π·Π°Π», Ρ‡Ρ‚ΠΎ Π½Π° участкС изысканий ΡˆΠΈΡ€ΠΎΠΊΠΎ Ρ€Π°Π·Π²ΠΈΡ‚ процСсс подтоплСния, ΠΊΠΎΡ‚ΠΎΡ€Ρ‹ΠΉ Π±ΡƒΠ΄Π΅Ρ‚ ΠΎΠΊΠ°Π·Ρ‹Π²Π°Ρ‚ΡŒ большоС влияниС Π½Π° ΠΏΡ€ΠΎΠ΅ΠΊΡ‚ΠΈΡ€ΠΎΠ²Π°Π½ΠΈΠ΅ ΠΈ ΡΠΊΡΠΏΠ»ΡƒΠ°Ρ‚Π°Ρ†ΠΈΡŽ сооруТСния. Π’ Ρ€Π°Π±ΠΎΡ‚Π΅ Π±Ρ‹Π» использован ΠΌΠ΅Ρ‚ΠΎΠ΄ вСроятностной ΠΎΡ†Π΅Π½ΠΊΠΈ для обоснованного раздСлСния Ρ‚Π΅Ρ€Ρ€ΠΈΡ‚ΠΎΡ€ΠΈΠΈ. Π’ Ρ€Π΅Π·ΡƒΠ»ΡŒΡ‚Π°Ρ‚Π΅ исслСдования Π±Ρ‹Π»ΠΈ Π²Ρ‹Π΄Π΅Π»Π΅Π½Ρ‹ Ρ‚Ρ€ΠΈ таксона, Ρ…Π°Ρ€Π°ΠΊΡ‚Π΅Ρ€ΠΈΠ·ΡƒΡŽΡ‰ΠΈΠ΅ΡΡ ΠΊΠ°ΠΊ ΠΏΠΎΠ΄Ρ‚ΠΎΠΏΠ»Π΅Π½Π½Ρ‹Π΅ Ρ‚Π΅Ρ€Ρ€ΠΈΡ‚ΠΎΡ€ΠΈΠΈ, ΠΏΠΎΡ‚Π΅Π½Ρ†ΠΈΠ°Π»ΡŒΠ½ΠΎ подтопляСмыС ΠΈ нСподтопляСмыС Π² силу своСго гСологичСского строСния. Π Π΅ΠΊΠΎΠΌΠ΅Π½Π΄ΠΎΠ²Π°Π½Ρ‹ мСроприятия ΠΏΠΎ сниТСнию Π½Π΅Π³Π°Ρ‚ΠΈΠ²Π½ΠΎΠ³ΠΎ влияния процСссов подтоплСния

    HERPES SIMPLEX VIRUS

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    Herpes infection is the most common infection among the adult population. The causative agent of the disease is Herpes simplex virus, which affects the skin, nerve cells, and human mucous membranes. Once in the human body, pathogens accumulate and manifest themselves with a weakened immune system

    VIRUSES IN THE BIOLOGICAL WORLD

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