212 research outputs found
Milestones chemical technology institute: our past and present
The article is devoted to the 95th anniversary of the Chemical technological Institute (CTI) of the Ural Federal University named after the first President of Russia B. N. Yeltsin (UrFU), which will be held in October 2015. Over the years Chemical technological Institute (CTI) has undergone many structure transformations in accordance with the tasks which were set before it the time and the development of our country. Currently this is a fairly large educational and research Institute, which employs more than 100 lecturers including more than 70 associate professors β candidates (PhD), 30 professors β doctors of Sciences (Hb), 3 academics and 1 corresponding member of RAS, trained more than 850 students
Homeward Bound: How Translators Negotiate the Foreign in Travel and Tourism. An English-Russian Case Study.
My research addresses intercultural communication in the field of travel and the industry of tourism and the challenges faced by translators between cultures. In my thesis I explore selected texts about foreign travel in English and in Russian and their Russian and English translations (respectively) in order to show the importance of differentiating between the ways in which translators, travellers and tourists represent and contrast foreign and domestic elements. In Chapters One and Two, I explore target-oriented and source-oriented translations. My analysis suggests that target-oriented translation can be creatively combined with source-oriented translation, both on a semantic level, by translators of travel texts and on a narrative level, by those travellers who write accounts of their experiences. Thus translators of travel literature create a holistic image of a foreign culture using analogies familiar to readers of the target language. My comparisons of English-language The Lonely Planet and Rough Guides travel guides to China, Finland and Russia with their Russian translations suggest that texts targeted at different audiences can be significantly divergent in terms of content. Translators take different approaches not only in their use of target-oriented and source-oriented translations, but also in the degree of creativity and adaptation/localization which they employ. My analysis of articles from British Cereal magazine and their Russian translations, which I study in Chapter Three of my thesis, shows that creativity may be a legitimate aspect of translation strategy, or an attempt by publishers to alter the original text radically in order to make it more appealing to the target audience. In Chapter Four, I focus my analysis of online texts for tourists on CondΓ© Nast Traveller magazine and the Booking.Com website (both English and Russian versions) in order to establish why localization experts replace translators. My thesis concludes that the role of the translator in the travel industry encompasses a spectrum of linguistic and extra-linguistic tasks based on connections between foreign and domestic values, including strategies of localization and adaptation
AKMEOLOGICHESKOJ APPROACH AS FORMING PROCESSES RESEARCH METHODOLOGY AKMEOLOGICHESKOJ POTENTIAL FUTURE MANAGER IN HIGH SCHOOL
In this work the illustration of use of acmeological approach is presented when training future managers in higher education institution. The essence of acmeological approach reveals and social need of its use for higher education with a support on researches of the Moscow and St. Petersburg acmeological schools is proved. Due to the realization of this approach need of reconsideration of elements of pedagogical process locates in higher education institution (the purposes, the principles, the contents, forms, methods, means, conditions and result).ΠΡΠ΅Π΄ΡΡΠ°Π²Π»Π΅Π½Ρ ΡΠ΅Π·ΡΠ»ΡΡΠ°ΡΡ ΠΏΡΠΈΠΌΠ΅Π½Π΅Π½ΠΈΡ Π°ΠΊΠΌΠ΅ΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ ΠΏΠΎΠ΄Ρ
ΠΎΠ΄Π° ΠΏΡΠΈ ΠΎΠ±ΡΡΠ΅Π½ΠΈΠΈ Π±ΡΠ΄ΡΡΠΈΡ
ΠΌΠ΅Π½Π΅Π΄ΠΆΠ΅ΡΠΎΠ² Π² Π²ΡΠ·Π΅. Π Π°ΡΠΊΡΡΠ²Π°Π΅ΡΡΡ ΡΡΡΠ½ΠΎΡΡΡ Π°ΠΊΠΌΠ΅ΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ ΠΏΠΎΠ΄Ρ
ΠΎΠ΄Π° ΠΈ Π΄ΠΎΠΊΠ°Π·ΡΠ²Π°Π΅ΡΡΡ ΡΠΎΡΠΈΠ°Π»ΡΠ½Π°Ρ Π½Π΅ΠΎΠ±Ρ
ΠΎΠ΄ΠΈΠΌΠΎΡΡΡ Π΅Π³ΠΎ ΠΈΡΠΏΠΎΠ»ΡΠ·ΠΎΠ²Π°Π½ΠΈΡ Π² Π²ΡΡΡΠ΅ΠΌ ΠΏΡΠΎΡΠ΅ΡΡΠΈΠΎΠ½Π°Π»ΡΠ½ΠΎΠΌ ΠΎΠ±ΡΠ°Π·ΠΎΠ²Π°Π½ΠΈΠΈ, Ρ ΠΎΠΏΠΎΡΠΎΠΉ Π½Π° ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ ΠΠΎΡΠΊΠΎΠ²ΡΠΊΠΎΠΉ ΠΈ Π‘Π°Π½ΠΊΡ-ΠΠ΅ΡΠ΅ΡΠ±ΡΡΠ³ΡΠΊΠΎΠΉ Π°ΠΊΠΌΠ΅ΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈΡ
ΡΠΊΠΎΠ». Π ΡΠ²ΡΠ·ΠΈ Ρ ΡΠ°ΠΊΠΈΠΌ ΠΏΡΠΈΠΌΠ΅ΡΠΎΠΌ ΡΠ΅Π°Π»ΠΈΠ·Π°ΡΠΈΠΈ Π°ΠΊΠΌΠ΅ΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ ΠΏΠΎΠ΄Ρ
ΠΎΠ΄Π° Π² Π²ΡΠ·Π΅ ΠΎΠ±ΠΎΡΠ½ΠΎΠ²ΡΠ²Π°Π΅ΡΡΡ Π½Π΅ΠΎΠ±Ρ
ΠΎΠ΄ΠΈΠΌΠΎΡΡΡ ΠΏΠ΅ΡΠ΅ΠΎΡΠΌΡΡΠ»Π΅Π½ΠΈΡ ΡΠ»Π΅ΠΌΠ΅Π½ΡΠΎΠ² ΠΏΠ΅Π΄Π°Π³ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ ΠΏΡΠΎΡΠ΅ΡΡΠ° (ΡΠ΅Π»Π΅ΠΉ, ΠΏΡΠΈΠ½ΡΠΈΠΏΠΎΠ², ΡΠΎΠ΄Π΅ΡΠΆΠ°Π½ΠΈΡ, ΡΠΎΡΠΌ, ΠΌΠ΅ΡΠΎΠ΄ΠΎΠ², ΡΡΠ΅Π΄ΡΡΠ², ΡΡΠ»ΠΎΠ²ΠΈΠΉ ΠΈ ΡΠ΅Π·ΡΠ»ΡΡΠ°ΡΠ°)
Nuclear BK channels regulate CREB phosphorylation in RAW264.7 macrophages
BACKGROUND: Macrophages are important cells of the innate immune system and contribute to a variety of physiological and pathophysiological responses. Monovalent and divalent ion channels have been studied in macrophage function, and while much research is still required, a role for these channels is beginning to emerge in macrophages. In addition to the plasma membrane, ion channels are also found in intracellular membranes including mitochondrial, lysosomal and nuclear membranes. While studying the function of plasma membrane located large conductance voltage- and calcium-activated potassium channels (BK channels) in a macrophage cell line RAW264.7, we became aware of the expression of these ion channels in other cellular locations. METHODS: Immunofluorescence and Western blot analysis were used to identify the expression of BK channels. To demonstrate a functional role for the nuclear located channel, we investigated the effect of the lipid soluble BK channel inhibitor paxilline on CREB phosphorylation. RESULTS: Treatment of resting macrophages with paxilline resulted in increased CREB phosphorylation. To confirm a role for nuclear BK channels, these experiments were repeated in isolated nuclei and similar results were found. Ca2+ and calmodulin-dependent kinases (CaMK) have been demonstrated to regulate CREB phosphorylation. Inhibition of CaMKII and CaMKIV resulted in the reversal of paxilline-induced CREB phosphorylation. CONCLUSIONS: These results suggest that nuclear BK channels regulate CREB phosphorylation in macrophages. Nuclear located ion channels may therefore be part of novel signalling pathways in macrophages and should be taken into account when studying the role of ion channels in these and other cells
The influence of the industrial complex on the atmospheric air in the Sverdlovsk region
The work is dedicated to studying the level dynamics of polluting substances emissions into the atmosphere of Yekaterinburg city and the Sverdlovsk region in the period of 2012-2016. In the process of our work we found out an insignificant reduction of main indicators values such as SI, HR, and IPA to estimate the atmospheric air quality. Nevertheless, the level of the air pollution in Yekaterinburg city remained high in the stated period. We also suggested some methods to reduce enterprises emissions in the article, which will lead to improving the air quality. In the result of our work it was established that the main pollutants are suspended particles, nitrogen dioxides, phenol, and benzene. Moreover, the connection between the atmospheric air pollution degree and the Sverdlovsk region population's health was determined. Β© 2018 Institute of Physics Publishing. All rights reserved
Documented procedure Β«Control of nonconforming productΒ» in anticipation of the re-certification of the management system of the organization
Π Π΅ΡΠ΅ΡΡΠΈΡΠΈΠΊΠ°ΡΠΈΡ ΡΠΈΡΡΠ΅ΠΌΠ° ΠΌΠ΅Π½Π΅Π΄ΠΆΠΌΠ΅Π½ΡΠ° ΠΎΡΠ³Π°Π½ΠΈΠ·Π°ΡΠΈΠΈ Π½Π° ΡΠΎΠΎΡΠ²Π΅ΡΡΡΠ²ΠΈΠ΅ ΡΡΠ΅Π±ΠΎΠ²Π°Π½ΠΈΡΠΌ ΠΠΠ‘Π’ Π ΠΠ‘Π 9001:2015 ΠΎΠ±ΡΠ·ΡΠ²Π°Π΅Ρ ΠΎΠ±Π½ΠΎΠ²Π»ΡΡΡ ΠΈ Π°ΠΊΡΡΠ°Π»ΠΈΠ·ΠΈΡΠΎΠ²Π°ΡΡ Π΄ΠΎΠΊΡΠΌΠ΅Π½ΡΠ°ΡΠΈΡ Π‘ΠΠ Π΄Π»Ρ ΡΠ΅Π·ΡΠ»ΡΡΠ°ΡΠΈΠ²Π½ΠΎΠ³ΠΎ ΠΈ ΡΡΡΠ΅ΠΊΡΠΈΠ²Π½ΠΎΠ³ΠΎ ΠΏΡΠΎΡ
ΠΎΠΆΠ΄Π΅Π½ΠΈΡ ΠΊΠ°ΠΊ Π²Π½ΡΡΡΠ΅Π½Π½Π΅Π³ΠΎ, ΡΠ°ΠΊ ΠΈ Π²Π½Π΅ΡΠ½Π΅Π³ΠΎ Π°ΡΠ΄ΠΈΡΠ°Recertification of the organization's management system for compliance with GOST R ISO 9001:2015 requires to update or keep current the documentation of the QMS for efficient and ef-fective flow of both internal and external audi
ΠΠ½ΠΆΠ΅Π½Π΅ΡΠ½ΠΎ-Π³Π΅ΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΎΠ΅ ΡΠ°ΠΉΠΎΠ½ΠΈΡΠΎΠ²Π°Π½ΠΈΠ΅ ΡΡΠ°ΡΡΠΊΠ° ΠΆΠ΅Π»Π΅Π·Π½ΠΎΠΉ Π΄ΠΎΡΠΎΠ³ΠΈ ΠΌΠ΅ΡΠΎΠ΄ΠΎΠΌ Π²Π΅ΡΠΎΡΡΠ½ΠΎΡΡΠ½ΠΎΠΉ ΠΎΡΠ΅Π½ΠΊΠΈ ΠΊΠ»Π°ΡΡΠΈΡΠΈΠΊΠ°ΡΠΈΠΎΠ½Π½ΠΎΠ³ΠΎ ΠΏΠΎΠΊΠ°Π·Π°ΡΠ΅Π»Ρ
The article describes the special engineering-geological zoning method of the railway territory. Permafrost geocryological conditions of the railway geological section were analyzed. The area is characterized by sporadic discontinuous permafrost. The analysis showed that the process of flooding is widely developed at the stusy area. It will have a great impact on the design and operation of the structure. The method of probabilistic assessment was used for a reasonable zonation of the territory. In result of the study, three taxa were identified that allows defining the flooded, potentially flooded, and non-flooded areas according to their geological structure. Measures for reducing the negative impact of flooding processes are recommended.ΠΠ·Π»ΠΎΠΆΠ΅Π½Π° ΠΌΠ΅ΡΠΎΠ΄ΠΈΠΊΠ° ΡΠΏΠ΅ΡΠΈΠ°Π»ΡΠ½ΠΎΠ³ΠΎ ΠΈΠ½ΠΆΠ΅Π½Π΅ΡΠ½ΠΎ-Π³Π΅ΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ ΡΠ°ΠΉΠΎΠ½ΠΈΡΠΎΠ²Π°Π½ΠΈΡ ΡΠ΅ΡΡΠΈΡΠΎΡΠΈΠΈ ΠΆΠ΅Π»Π΅Π·Π½ΠΎΠ΄ΠΎΡΠΎΠΆΠ½ΠΎΠ³ΠΎ ΠΏΡΡΠΈ. ΠΠ»Ρ ΡΡΠΎΠ³ΠΎ Π±ΡΠ»ΠΈ ΠΏΡΠΎΠ°Π½Π°Π»ΠΈΠ·ΠΈΡΠΎΠ²Π°Π½Ρ Π³Π΅ΠΎΠΊΡΠΈΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈΠ΅ ΡΡΠ»ΠΎΠ²ΠΈΡ ΡΡΠ°ΡΡΠΊΠ° ΠΆΠ΅Π»Π΅Π·Π½ΠΎΠΉ Π΄ΠΎΡΠΎΠ³ΠΈ Β«ΠΠ°Π½Π³ΠΎΠ΄Ρ β ΠΠΎΠ²ΡΠΉ Π£ΡΠ΅Π½Π³ΠΎΠΉΒ», Ρ
Π°ΡΠ°ΠΊΡΠ΅ΡΠΈΠ·ΡΡΡΠΈΠ΅ΡΡ ΠΎΡΡΡΠΎΠ²Π½ΡΠΌ ΡΠ°ΡΠΏΡΠΎΡΡΡΠ°Π½Π΅Π½ΠΈΠ΅ΠΌ ΠΌΠ½ΠΎΠ³ΠΎΠ»Π΅ΡΠ½Π΅ΠΌΠ΅ΡΠ·Π»ΡΡ
ΠΏΠΎΡΠΎΠ΄. ΠΠ½Π°Π»ΠΈΠ· ΠΏΠΎΠΊΠ°Π·Π°Π», ΡΡΠΎ Π½Π° ΡΡΠ°ΡΡΠΊΠ΅ ΠΈΠ·ΡΡΠΊΠ°Π½ΠΈΠΉ ΡΠΈΡΠΎΠΊΠΎ ΡΠ°Π·Π²ΠΈΡ ΠΏΡΠΎΡΠ΅ΡΡ ΠΏΠΎΠ΄ΡΠΎΠΏΠ»Π΅Π½ΠΈΡ, ΠΊΠΎΡΠΎΡΡΠΉ Π±ΡΠ΄Π΅Ρ ΠΎΠΊΠ°Π·ΡΠ²Π°ΡΡ Π±ΠΎΠ»ΡΡΠΎΠ΅ Π²Π»ΠΈΡΠ½ΠΈΠ΅ Π½Π° ΠΏΡΠΎΠ΅ΠΊΡΠΈΡΠΎΠ²Π°Π½ΠΈΠ΅ ΠΈ ΡΠΊΡΠΏΠ»ΡΠ°ΡΠ°ΡΠΈΡ ΡΠΎΠΎΡΡΠΆΠ΅Π½ΠΈΡ. Π ΡΠ°Π±ΠΎΡΠ΅ Π±ΡΠ» ΠΈΡΠΏΠΎΠ»ΡΠ·ΠΎΠ²Π°Π½ ΠΌΠ΅ΡΠΎΠ΄ Π²Π΅ΡΠΎΡΡΠ½ΠΎΡΡΠ½ΠΎΠΉ ΠΎΡΠ΅Π½ΠΊΠΈ Π΄Π»Ρ ΠΎΠ±ΠΎΡΠ½ΠΎΠ²Π°Π½Π½ΠΎΠ³ΠΎ ΡΠ°Π·Π΄Π΅Π»Π΅Π½ΠΈΡ ΡΠ΅ΡΡΠΈΡΠΎΡΠΈΠΈ. Π ΡΠ΅Π·ΡΠ»ΡΡΠ°ΡΠ΅ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ Π±ΡΠ»ΠΈ Π²ΡΠ΄Π΅Π»Π΅Π½Ρ ΡΡΠΈ ΡΠ°ΠΊΡΠΎΠ½Π°, Ρ
Π°ΡΠ°ΠΊΡΠ΅ΡΠΈΠ·ΡΡΡΠΈΠ΅ΡΡ ΠΊΠ°ΠΊ ΠΏΠΎΠ΄ΡΠΎΠΏΠ»Π΅Π½Π½ΡΠ΅ ΡΠ΅ΡΡΠΈΡΠΎΡΠΈΠΈ, ΠΏΠΎΡΠ΅Π½ΡΠΈΠ°Π»ΡΠ½ΠΎ ΠΏΠΎΠ΄ΡΠΎΠΏΠ»ΡΠ΅ΠΌΡΠ΅ ΠΈ Π½Π΅ΠΏΠΎΠ΄ΡΠΎΠΏΠ»ΡΠ΅ΠΌΡΠ΅ Π² ΡΠΈΠ»Ρ ΡΠ²ΠΎΠ΅Π³ΠΎ Π³Π΅ΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ ΡΡΡΠΎΠ΅Π½ΠΈΡ. Π Π΅ΠΊΠΎΠΌΠ΅Π½Π΄ΠΎΠ²Π°Π½Ρ ΠΌΠ΅ΡΠΎΠΏΡΠΈΡΡΠΈΡ ΠΏΠΎ ΡΠ½ΠΈΠΆΠ΅Π½ΠΈΡ Π½Π΅Π³Π°ΡΠΈΠ²Π½ΠΎΠ³ΠΎ Π²Π»ΠΈΡΠ½ΠΈΡ ΠΏΡΠΎΡΠ΅ΡΡΠΎΠ² ΠΏΠΎΠ΄ΡΠΎΠΏΠ»Π΅Π½ΠΈΡ
HERPES SIMPLEX VIRUS
Herpes infection is the most common infection among the adult population. The causative agent of the disease is Herpes simplex virus, which affects the skin, nerve cells, and human mucous membranes. Once in the human body, pathogens accumulate and manifest themselves with a weakened immune system
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