402 research outputs found

    Crossing the Bridge : The Sound of Istanbul

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    Ebenso wie sein Vorbild Martin Scorsese (THE LAST WALTZ, 1978; SHINE A LIGHT, 2008) drehte Fatih Akin mit CROSSING THE BRIDGE: THE SOUND OF ISTANBUL ein Rockumentary, das einen emotionalen Strudel erzeugt und den Zuschauer sehr nah ans Geschehen bringt. Anders aber als Scorsese, der in SHINE A LIGHT den Mythos „Rolling Stones“ feiert und somit sein Publikum sicher hat, begibt sich Akin auf eine Reise ins Unbekannte. Die Musikszene Istanbuls, die er porträtiert, ist für die meisten Europäer Neuland

    Toxicity and toxicokinetics of cadmium in \u3ci\u3eCapitella\u3c/i\u3e sp. I: Relative importance of water and sediment as routes of cadmium uptake

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    The importance of dissolved versus sediment-bound cadmium as uptake routes for the deposit-feeding polychaete Capitella species I and the toxicity and toxicokinetics of cadmium from these exposure routes were investigated. Effects were reported as changes in worm growth rate, egestion rate and allometry. Radioactive cadmium (109Cd) was used as a tracer to examine the uptake (5 d) and subsequent depuration (6 d) of cadmium. Both effects and kinetics were investigated in systems with and without sediment. Individual Capitella sp. I were exposed to (1) dissolved (i.e. –1). Worms in water-only treatments showed negative growth rates, which decreased linearly from –5 to –10% d–1 with increasing cadmium concentration. Cadmium had no detectable effect on egestion rate or growth in the presence of sediment in either sediment-bound only (ca 36% d–1) or porewater & sediment (ca 30% d–1) treatments. Cadmium exposure had no detectable effect on the allometric exponent (i. e. area-length relation) in any of the treatments; however, worms in water-only treatments were relatively thinner than in the 2 treatments with sediment. Worms in porewater & sediment treatments took up ca 50-fold more cadmium (ca 195 ng Cd worm–1) than worms in water-only treatments (3.9 ng Cd worm–1) during 5 d of exposure. Sediment-bound cadmium was calculated to contribute 95 % of the total amount taken up by feeding worms. Starving worms retained all of the cadmium during the subsequent depuration period (6 d), and exhibited an increased weight-specific body burden (μg Cd g–1 dry wt worm) due to shrinkage. In feeding worms, the decrease in weight-specific body burden was faster (T½ = 3 d) than the decrease in total body burden (μg Cd worm–1; T½ = 11 d), indicating that both active excretion and dilution of cadmium body burden as a result of growth contributed to the change in cadmium tissue concentration during the depuration period. Thus, our results indicate that in Capitella sp. I sediment-bound cadmium is the major route of uptake. We found that cadmium affects starving but not fed worms, despite the fact that fed worms took up considerably more cadmium than starving worms. Our results suggest that stress associated with food limitation increases the susceptibility of worms to cadmium stress

    Toxicity and toxicokinetics of cadmium in \u3ci\u3eCapitella\u3c/i\u3e sp. I: Relative importance of water and sediment as routes of cadmium uptake

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    The importance of dissolved versus sediment-bound cadmium as uptake routes for the deposit-feeding polychaete Capitella species I and the toxicity and toxicokinetics of cadmium from these exposure routes were investigated. Effects were reported as changes in worm growth rate, egestion rate and allometry. Radioactive cadmium (109Cd) was used as a tracer to examine the uptake (5 d) and subsequent depuration (6 d) of cadmium. Both effects and kinetics were investigated in systems with and without sediment. Individual Capitella sp. I were exposed to (1) dissolved (i.e. –1). Worms in water-only treatments showed negative growth rates, which decreased linearly from –5 to –10% d–1 with increasing cadmium concentration. Cadmium had no detectable effect on egestion rate or growth in the presence of sediment in either sediment-bound only (ca 36% d–1) or porewater & sediment (ca 30% d–1) treatments. Cadmium exposure had no detectable effect on the allometric exponent (i. e. area-length relation) in any of the treatments; however, worms in water-only treatments were relatively thinner than in the 2 treatments with sediment. Worms in porewater & sediment treatments took up ca 50-fold more cadmium (ca 195 ng Cd worm–1) than worms in water-only treatments (3.9 ng Cd worm–1) during 5 d of exposure. Sediment-bound cadmium was calculated to contribute 95 % of the total amount taken up by feeding worms. Starving worms retained all of the cadmium during the subsequent depuration period (6 d), and exhibited an increased weight-specific body burden (μg Cd g–1 dry wt worm) due to shrinkage. In feeding worms, the decrease in weight-specific body burden was faster (T½ = 3 d) than the decrease in total body burden (μg Cd worm–1; T½ = 11 d), indicating that both active excretion and dilution of cadmium body burden as a result of growth contributed to the change in cadmium tissue concentration during the depuration period. Thus, our results indicate that in Capitella sp. I sediment-bound cadmium is the major route of uptake. We found that cadmium affects starving but not fed worms, despite the fact that fed worms took up considerably more cadmium than starving worms. Our results suggest that stress associated with food limitation increases the susceptibility of worms to cadmium stress

    Nanomaterials in the aquatic environment: A European Union-United States perspective on the status of ecotoxicity testing, research priorities, and challenges ahead

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    The US-EU Community of Research (CoR) was established in 2012 to provide a platform for scientists to develop a ‘shared repertoire of protocols and methods to overcome nanotechnology environmental health and safety (nanoEHS) research gaps and barriers’ (www.us-eu.org/). Based on work within the Ecotoxicology CoR (2012–2015) we provide here an overview of the state-of-the-art of nanomaterials (NMs) in the aquatic environment by addressing different research questions with a focus on ecotoxicological test systems and the challenges faced when assessing nanomaterial (NM) hazards (e.g., uptake routes, bioaccumulation, toxicity, test protocols and model organisms). Our recommendation is to place particular importance on studying the ecological effects of aged/weathered NMs, as-manufactured NMs, as well as NMs released from consumer products in addressing the following overarching research topics: i) NM characterization and quantification in environmental and biological matrices, ii) NM transformation in the environment and consequences for bioavailability and toxicity, iii) alternative methods to assess exposure, iv) influence of exposure scenarios on bioavailability and toxicity, v) development of more environmentally realistic bioassays and vi) uptake, internal distribution, and depuration of NMs. Research addressing these key topics will reduce uncertainty in ecological risk assessment and support the sustainable development of nanotechnology

    The internal quality focus as a starting point for the introduction of a quality management system for health care services

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    Anhand des Qualitätsbegriffs werden Kennzeichen ergotherapeutischer Dienstleistungen herausgearbeitet, um die Ergotherapie anhand einzelner Qualitätsmerkmale einzuordnen. Zur Vorbereitung der Ausrichtung eines Qualitätsmanagement- Systems werden bestehende Qualitätsmodelle hinsichtlich verschiedener Qualitätsorientierungen analysiert. Zur jeweiligen Konzeption wird ihre Abhängigkeit vom Standort des Betrachters und von seiner Blickrichtung auf ein System postuliert und diskutiert. Ziel der Auseinandersetzung mit einzelnen Qualitätsmodellen ist die Erarbeitung eines Modells zur Identifikation und Erweiterung der persönlichen Qualitätsorientierung von Mitarbeitern ergotherapeutischer Einzelpraxen (EEP) Als Ergebnis wird eine Konzeption für EEP vorgeschlagen, die auf die Neugestaltung von Teamprozessen und den Aufbau kollegialer Erfolgskontrolle fokussiert. Spezielle Rahmenbedingungen der EEP, sowie Voraussetzungen und Erfolgsfaktoren in Anlehnung an die Vorgehensweise der Organisationsentwicklung, werden in der Konzeption berücksichtigt. Zur Umsetzung einzelner Ablaufschritte werden Analyseinstrumente unter Beteiligung der Mitarbeiterinnen und Mitarbeiter entwickelt und erprobt. Erhobene Daten werden zusammengestellt und organisationspsychologische Besonderheiten ergotherapeutischer Tätigkeiten herausgearbeitet, um demjenigen, der in diesem Feld Veränderungsprozesse anregen möchte, Hilfestellung anzubieten.Flags of occupational therapy services are worked out on the basis of the quality term, in order to arrange the occupational therapy (OT) on the basis of individual quality criteria. For the preparation of a quality adjustment management system of existing quality models are analyzed regarding different quality focus. For respective conception its dependency on the location of the viewer and on its line of sight is postulated and discussed. Target of the argument concerning individual quality models lies in the development of a model for the identification and extension of the personal quality focus of employees in OT- Single- Institutions (OTSI). As a result a conception for OTSI is suggested, which focuses on the reorganization of team processes and the structure of team focussed progress control. Special basic conditions of the OTSI are considered in the conception, as well as prerequisites and success factors following the methodology of the organizational development. For the conversion of an individual step, analysis instruments are developed and tested under participation of the employees. Raised data is arranged and organization-psychological special features of occupational therapists activities are worked out. This system enables an assisting modification process if needed for health care services

    Microfluidics for Molecular Measurements and Quantitative Distributable Diagnostics

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    A major challenge in global health care is a lack of portable and affordable quantitative diagnostic devices. This is because classic quantification of biomolecules is typically performed using kinetic assays that require strict control only found in controlled laboratory environments. By using the power of microfluidics, quantitative assays can be performed robustly in a "digital" format that is decoupled from precise kinetics through highly parallelized qualitative reactions. The benefits of performing quantitative assays in a digital format extend beyond just assay robustness to reduction of instrumental complexity, increase in quantitative precision, and an increase in the amount of information that can be gained from a single experiment. These microfluidic architectures, however, are not limited to usage in scenarios of quantification of biomolecules. These architectures can also potentially be extended to answering complex biological questions in single cells, such as determining the 3-dimensional organization of nuclear DNA and RNA

    Crip Pessimism: The Language of Dis/ability and the Culture that Isn\u27t

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    New labour's ethical dimension: Statistical trends in Tony Blair's foreign policy speeches

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    Debate has raged over the extent to which New Labour has succeeded in incorporating an ethical dimension in British foreign policy. The assumption has been that New Labour at least changed the context of foreign policy by adopting a more moralistic language. However, there has been no attempt as yet to show this statistically. Using computer-assisted content analysis of Margaret Thatcher's, Robin Cook's and Tony Blair's foreign policy speeches, and assuming that Blair, as opposed to Cook, is the representative voice of New Labour, this research finds that New Labour has indeed changed the context significantly. However, this change did not occur until after the events of 9/11. © 2010 The Authors. Journal compilation © 2010 Political Studies Association
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