55 research outputs found
Challenges and Barriers Recruitment of Professionals and Management Trainees in a Transitional Situation to the New Normal
The purpose of this study is to find out the obstacles faced in recruiting professional and management trainees in the transition situation to the new normal. Competition in the global business world requires company management to be more concerned in managing human resources in it. However, in the new normal situation, several challenges and obstacles in professional recruitment are difficult to attract Candidates with the Right Qualifications, Incomplete Company-Related Information, Ineffective Channels Used, Limited Access to Required Devices and others. All recruitment processes including selection can be done online, the right solution during a pandemic
ANALYSIS OF TRADITIONAL HEALTH CARE IN THREE COMMUNITY HEALTH CENTERS IN WEST JAVA PROVINCE, INDONESIA, 2018
The National Traditional Health Care set up three objectives for its implementation at the health centers, whereby health staff to be trained on traditional health and provide accupressure care, able to collect data, register and provide technical guidance to traditional healers and guide individuals in the use of traditional medicine and herbs. This qualitative research aimed to analyze the implementation of traditional health care at 3 subdistrict health centers Ciomas, Ciawi and Caringin in district Bogor. Data was collected through document analysis, observation and indepth inteview. Each health center has trained staff in accupressure but care is hindered by lack of room and community prefers to go to traditional masseur. Data collection, registration and technical guidance to traditional healers exist due to support from local funding. Individual guidance on the use of traditional medicine and herbs do not happen due to no fund for home visits. Traditional health care at health centers to focus on the activity that is working which is data collection, registration and technical guidance to traditional healers. District Health Office Bogor should develop local policy and Standard Operating Procedure for traditional health care at health centers
Penilaian analisa enzim dan isoenzim dalam diagnosa penyakit infarksi miokardia
Reference ranges for the following 1 cardiac 1 enzymes and isoenzymes were established, using sera from 99 patients attending the USM outpatients departments: Creatine kinase (CK),lactate dehydrogenase (LD),aspartate aminotransferase (AST),creatine kinase-MB isoenzyme (CKMB) and 5 lactate dehydrogenase isoenzymes (LD1,LD2,LD4 and LD5).The reference ranges for LD1/LD2 ratio, LD1 expressed as percentage of total LD ( LD1%); and LD1 expressed as enzyme activity in International Units LD (IU) were also determined.67 patients who were admitted to the cardiac care unit with suspicion of myocardial infarction were analysed for the above "cardiac" enzymes and isoenzymes. Out of the 67 patients who were admitted to the cardiac care unit ·40 were diagnosed positive and 27 as negative for myocardial infarction. Using the established reference ranges and the diagnoses (positive or negative for myocardial infarction), we determined the sensitivities, specificities and efficiencies for each of the above enzyme/isoenzyme/isoenzyme ratios, at 0-12 hr,
13-24 hr,25-48 hr, and 49-92 hr after the onset of chest pain.For all the above enzymatic parameters the sensitivities were low (42.4 to 68.6) at the interval
0-12 hr, and progressively increased at 13-24 hr (58.7 to 87.1), 25-48 hr (81.1 to 96.9), and 49-92 hr (82.4 to 100) after onset of chest pain. The specificities were higher than sensitivities at 0-12 hr (74.1-100), and 13-24 hr (89.5-96.6). Beyond 25 hr after the onset of chest pain, the specificities were camparable to 13-24 hr except for
LD and ID1 ( IU), which had lower specificities compared to earlier pericxis. In general, the best combinations of sensitivities and specificities was during 13-48 hr after onset of chest pain.Based on our data on sensitivities
and specificies, it would appear that routine determination of CK-M8 or LD isoenzymes may not be necessary in the diagnosis of most cases of myocardial infarction
The study of glucose-6-phosphate dehydrogenase (G6PD) gene by restriction enzyme by restriction enzyme digestion in the Kelantan population
The most common diseases producing enzymopathy affecting the human population is glucose-6-phosphate dehydrogenase (G6PD) deficiency. It is estimated that about 400 million people worldwide are affected and this disease is commonest seen in the tropical and subtropical zones of the Eastern hemisphere. Molecular analysis has confirmed that the basis for G6PD deficiency is widely heterogeneous. Different mutants are responsible for the G6PD deficiency in the various parts of the world where this abnormality is prevalent. This study involved a sequential analysis whereby the blood from Malay neonates with neonatal jaundice admitted to Hospital Universiti Sains Malaysia and Kota Bharu Hospital were analyzed and polymerase chain
reaction based analysis using serial multiplex primer method was done on those DNA samples. Samples that are
found to be abnormal were then sequenced. Out of the 45 samples studied, 8 were found to have the Mediterranean mutation, two have the Mahidol mutation, two have Canton
mutation and three have Kaiping mutation. Thus the molecular basis for the Malay neonatal jaundice in Kelantan is described with further prospect of population screening
Mitochondrial pseudogenes in the nuclear genome of Aedes aegypti mosquitoes: implications for past and future population genetic studies
<p>Abstract</p> <p>Background</p> <p>Mitochondrial DNA (mtDNA) is widely used in population genetic and phylogenetic studies in animals. However, such studies can generate misleading results if the species concerned contain nuclear copies of mtDNA (Numts) as these may amplify in addition to, or even instead of, the authentic target mtDNA. The aim of this study was to determine if Numts are present in <it>Aedes aegypti </it>mosquitoes, to characterise any Numts detected, and to assess the utility of using mtDNA for population genetics studies in this species.</p> <p>Results</p> <p>BLAST searches revealed large numbers of Numts in the <it>Ae. aegypti </it>nuclear genome on 146 supercontigs. Although the majority are short (80% < 300 bp), some Numts are almost full length mtDNA copies. These long Numts are not due to misassembly of the nuclear genome sequence as the Numt-nuclear genome junctions could be recovered by amplification and sequencing. Numt evolution appears to be a complex process in <it>Ae. aegypti </it>with ongoing genomic integration, fragmentation and mutation and the secondary movement of Numts within the nuclear genome.</p> <p>The PCR amplification of the putative mtDNA nicotinamide adenine dinucleotide dehydrogenase subunit 4 (<it>ND4</it>) gene from 166 Southeast Asian <it>Ae. aegypti </it>mosquitoes generated a network with two highly divergent lineages (clade 1 and clade 2). Approximately 15% of the <it>ND4 </it>sequences were a composite of those from each clade indicating Numt amplification in addition to, or instead of, mtDNA. Clade 1 was shown to be composed at least partially of Numts by the removal of clade 1-specific bases from composite sequences following enrichment of the mtDNA. It is possible that all the clade 1 sequences in the network were Numts since the clade 2 sequences correspond to the known mitochondrial genome sequence and since all the individuals that produced clade 1 sequences were also found to contain clade 2 mtDNA-like sequences using clade 2-specific primers. However, either or both sets of clade sequences could have Numts since the BLAST searches revealed two long Numts that match clade 2 and one long Numt that matches clade 1. The substantial numbers of mutations in cloned <it>ND4 </it>PCR products also suggest there are both recently-derived clade 1 and clade 2 Numt sequences.</p> <p>Conclusion</p> <p>We conclude that Numts are prevalent in <it>Ae. aegypti </it>and that it is difficult to distinguish mtDNA sequences due to the presence of recently formed Numts. Given this, future population genetic or phylogenetic studies in <it>Ae. aegypti </it>should use nuclear, rather than mtDNA, markers.</p
A dataset of fishes in and around Inle Lake, an ancient lake of Myanmar, with DNA barcoding, photo images and CT/3D models
ミャンマーの古代湖インレー湖で一世紀ぶりに魚類相調査, 約四割が外来魚。標本の3Dモデルもオンライン公開. 京都大学プレスリリース. 2016-12-02.Background: Inle (Inlay) Lake, an ancient lake of Southeast Asia, is located at the eastern part of Myanmar, surrounded by the Shan Mountains. Detailed information on fish fauna in and around the lake has long been unknown, although its outstanding endemism was reported a century ago
Fish diversity of a spring field in Hopong Town, Taunggyi District, Shan State, Myanmar (the Salween River Basin), with genetic comparisons to some “species endemic to Inle Lake”
Hopong, a small town in the Salween (Thanlwin) River Basin, Myanmar, is located 35 km northeast of Inle Lake, a famous ancient lake with numerous endemic fish species. We surveyed the fish fauna of a spring pond in Hopong in 2016, 2019 and 2020 and identified 25 species. Of these, seven, including Inlecypris auropurpureus and Sawbwa resplendens, had been considered endemic to Inle Lake and at least three species were genetically unique. Eight were suspected or definite introduced species, including Oreochromis niloticus and Gambusia affinis. We were unable to identify a nemacheilid species of the genus Petruichthys, which would need a taxonomic examination. The Hopong area is being developed rapidly and, hence, it is crucial to conserve its native fish species and the freshwater ecosystems
Clinical resolution of periodontitis among diabetic patients with chronic periodontitis co-morbidity under medical-dental coordinated care: a preliminary study in Kuantan
Clinical resolution of periodontitis (CRP) of type-2 diabetic patients with chronic
periodontitis (T2DM-PD) after receiving non-surgical periodontal treatment (NSPT) has been
reported in the previous studies. This study aimed to evaluate CRP of T2DM-PD under medicaldental
coordinated care (M-DCC). Materials and Methods: A 6-months follow-up quasi-experimental
study was conducted among 20 subjects who received M-DCC in 2016. M-DCC included standard
diabetic care provided by medical professional from 3 health clinics and NSPT provided by
periodontal specialists from two periodontal specialist clinics. Target glycemic control achievement
(TGCA) HbA1c 6.5% was assessed at baseline and 6 months after NSPT. Clinical resolution of PD was
measured in terms of BPE, BOP %, CAL(mm), PPD(mm), PPD 4mm, PPD =4 mm and PPD 6mm at
baseline, 3 and 6 months. Paired simple t test and ANOVA F test were applied to infer clinical
resolution of periodontitis and its relation to TGCA. Results: Mean (SD) of average BPE at baseline,
3- and 6-months were 3.52(0.34), 3.12(0.33) and 3(0.45) with (p<0.05); average PPD(mm) were
3.33(0.5), 3.23(0.75) and 2.73(0.57) with (p<0.05); PPD(%) 4mm were 71.03(12.33), 82.77(9.9) and
85.85 (8.9) with (p<0.05); PPD(%) =4 mm were 27.94(11.9), 16.97(10.01) and 13.71(9.1) with
(p<0.05) ; PPD(%) 6mm were 8.04(4.32), 2.66(2.3) and 1.87(2.32) with (p<0.05). Significant
resolution of BPE, CAL(mm) and PPD(mm) was noticed among two subjects who has changed from
uncontrolled TGCA to controlled TGCA. Conclusion(s): CRP and TGCA results have verified the
effectiveness of M-DCC. A further clinical control trial with adequate sample size needs to confirm
the results of the present study
Oral hygiene practices and periodontal disease status assessment among diabetic patients from three selected public medical primary care clinics in Kuantan, Malaysia
Evidences on the bilateral relationship between diabetes mellitus (DM) and periodontal disease (PD). Thus, the aim of this study was to assess periodontal disease status and oral hygiene of DM-patients from public medical care clinics (PMPCCs
Mesozoic origin and ‘out-of-India’ radiation of ricefishes (Adrianichthyidae)
The Indian subcontinent has an origin geologically different from Eurasia, but many terrestrial animal and plant species on it have congeneric or sister species in other parts of Asia, especially in the Southeast. This faunal and floral similarity between India and Southeast Asia is explained by either of the two biogeographic scenarios, ‘into-India’ or ‘out-of-India’. Phylogenies based on complete mitochondrial genomes and five nuclear genes were undertaken for ricefishes (Adrianichthyidae) to examine which of these two biogeographic scenarios fits better. We found that Oryzias setnai, the only adrianichthyid distributed in and endemic to the Western Ghats, a mountain range running parallel to the western coast of the Indian subcontinent, is sister to all other adrianichthyids from eastern India and Southeast–East Asia. Divergence time estimates and ancestral area reconstructions reveal that this western Indian species diverged in the late Mesozoic during the northward drift of the Indian subcontinent. These findings indicate that adrianichthyids dispersed eastward ‘out-of-India’ after the collision of the Indian subcontinent with Eurasia, and subsequently diversified in Southeast–East Asia. A review of geographic distributions of ‘out-of-India’ taxa reveals that they may have largely fuelled or modified the biodiversity of Eurasia.journal articl
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