Antioxidant activity and chemical constituents of Warionia saharae Benth. & Coss. (Compositae) from Algeria.

Phytochemical investigations of chloroform and ethyl acetate extracts from the aerial parts of Warionia saharae Benth. & Coss. from Algeria resulted in the isolation of ten known compounds: β-sitosterol, stigmasterol, scopoletin, cirsimaritin, chrysoeriol, hispidulin, luteolin, esculetin, (2R,3R) taxifolin, quercetin. Their structures were elucidated on the basis of extensive spectroscopic analysis and comparison with the related known compounds. The EtOAc extract which was evaluated for DPPH radical scavenging activity and of lipid peroxide inhibition showed potent antioxidant ability compared to the quercetin and ascorbic acid used as positive control

Ethno-nutraceutical survey of dietary seaweeds used in unconventional therapy in Morocco. An emerging practice for a renovated pharmacopeia

In Morocco, like in many developing countries, people usually tend to turn to unconventional therapies. An ethnophycological survey was realized to inventory seaweeds used in complementary Moroccan medicine. One hundred ninety-one (191) consumers and thirty-one (31) traditional healers were interviewed on seaweed food-related diseases using standardized questionnaires. The survey was conducted in some cities in Morocco. After gathering all the information, the data obtained were analyzed and summarized. The investigation has displayed emerging phycotherapy in Morocco. Consumers' knowledge about seaweeds is complex and various. Yet, most of them are convinced of their nutraceutical benefits for a healthy lifestyle. The healers strongly support the reliability of their recommendations in treating health problems according to what the literature shows. The present study has made a contribution in giving a clear picture of the status quo of dietary seaweeds therapies in Morocco, which is revealed as an emerging practice needed to renovate pharmacopeia. Therefore, it has allowed us to list some seaweeds that haven't been considered in any scientific investigation before, which will be subject afterward to pharmacological tests to prove the claimed uses

Antioxidant activity and chemical constituents of Warionia saharae Benth. & Coss. (Compositae) from Algeria.

International audiencePhytochemical investigations of chloroform and ethyl acetate extracts from the aerial parts of Warionia saharae Benth. &amp; Coss. from Algeria resulted in the isolation of ten known compounds: β-sitosterol, stigmasterol, scopoletin, cirsimaritin, chrysoeriol, hispidulin, luteolin, esculetin, (2R,3R) taxifolin, quercetin. Their structures were elucidated on the basis of extensive spectroscopic analysis and comparison with the related known compounds. The EtOAc extract which was evaluated for DPPH radical scavenging activity and of lipid peroxide inhibition showed potent antioxidant ability compared to the quercetin and ascorbic acid used as positive control.</p

Antioxidant activity and chemical constituents of Warionia saharae Benth. & Coss. (Compositae) from Algeria.

International audiencePhytochemical investigations of chloroform and ethyl acetate extracts from the aerial parts of Warionia saharae Benth. &amp; Coss. from Algeria resulted in the isolation of ten known compounds: β-sitosterol, stigmasterol, scopoletin, cirsimaritin, chrysoeriol, hispidulin, luteolin, esculetin, (2R,3R) taxifolin, quercetin. Their structures were elucidated on the basis of extensive spectroscopic analysis and comparison with the related known compounds. The EtOAc extract which was evaluated for DPPH radical scavenging activity and of lipid peroxide inhibition showed potent antioxidant ability compared to the quercetin and ascorbic acid used as positive control.</p

Chemical composition, in vitro antioxidant, anticholinesterase and antibacterial activities of Linaria scariosa Desf

The study was performed on the dichloromethane (DCM), ethyl acetate (EAc) and n-butanol (Bu) fractions (F) obtained from the 80% ethanol extract of Linaria scariosa Desf. aerial parts, collected in the North Eastern region of Algeria. Remarkable total phenolic and flavonoid contents were obtained, mainly for EAcF. These results were in accordance with the antioxidant activity of EAcF against DPPH, ABTS, CUPRAC and reducing power tests. DCMF and BuF exhibited significant cholinesterase activity inhibition of BChE and AChE. Moreover, EAcF displayed only moderate antibacterial activities, especially against S. aureus. The biological results were correlated to the chemical components, deduced by both GC-MS analysis of the fractions and the isolation of hemipholin, pectolinarigenin, antirride, antirrinoside, pectolinarin and linariosise, some of which known to exhibit potent effects on the tested biological activities. The study provides the first biological and chemical investigation on Linaria scariosa Desf (unresolved name)

Secondary Metabolites from Linaria tingitana

The genus Linaria belongs to the Scrophulariaceae family and comprises about 200 species [1]. It is represented by 39 in Algeria [2]; several species have been used in folk medicine as tonics, antiscorbutics, laxatives, antidiabetics, and diuretics [3, 4]. Previous work on this genus has shown the presence of iridoids, diterpenoids, flavonoids, alkaloids, and phenylethanoids [4–9].Peer Reviewe

Chemical constituents of Linaria reflexa Desf.(Scrophulariaceae)

The phytochemical study on the aerial parts of Linaria reflexa Desf., belonging to the scrophulariaceae family led the isolation and structural elucidation of pectolinarin (1), linariin (2), methyl linoleate (3), apigenin (4), mannitol (5) and pectolinarigenin (6). These compounds were identified by 1D and 2D NMR as well as by mass spectrometry.We are grateful to MESRS (DGRSDT) Algeria for financial supports.Peer Reviewe