7 research outputs found
PPPC 4 DM ID: A Poor Particle Physicist Cookbook for Dark Matter Indirect Detection
We provide ingredients and recipes for computing signals of TeV-scale Dark
Matter annihilations and decays in the Galaxy and beyond. For each DM channel,
we present the energy spectra of electrons and positrons, antiprotons,
antideuterons, gamma rays, neutrinos and antineutrinos e, mu, tau at
production, computed by high-statistics simulations. We estimate the Monte
Carlo uncertainty by comparing the results yielded by the Pythia and Herwig
event generators. We then provide the propagation functions for charged
particles in the Galaxy, for several DM distribution profiles and sets of
propagation parameters. Propagation of electrons and positrons is performed
with an improved semi-analytic method that takes into account
position-dependent energy losses in the Milky Way. Using such propagation
functions, we compute the energy spectra of electrons and positrons,
antiprotons and antideuterons at the location of the Earth. We then present the
gamma ray fluxes, both from prompt emission and from Inverse Compton scattering
in the galactic halo. Finally, we provide the spectra of extragalactic gamma
rays. All results are available in numerical form and ready to be consumed.Comment: 57 pages with many figures and tables. v4: updated to include a 125
higgs boson, computation and discussion of extragalactic spectra corrected,
some other typos fixed; all these corrections and updates are reflected on
the numerical ingredients available at
http://www.marcocirelli.net/PPPC4DMID.html they correspond to Release 2.
The effect of film thickness on the C40 TiSi2 to C54 TiSi 2 transition temperature
10.1149/1.2007107Journal of the Electrochemical Society15210G754-G756JESO
Some physiological alterations associated with pleiotropic cross resistance and collateral sensitivity in Saccharomyces cerevisiae
Association of a Nonmuscle Myosin II with Axoplasmic Organelles
Association of motor proteins with organelles is required for the motors to mediate transport. Because axoplasmic organelles move on actin filaments, they must have associated actin-based motors, most likely members of the myosin superfamily. To gain a better understanding of the roles of myosins in the axon we used the giant axon of the squid, a powerful model for studies of axonal physiology. First, a ∼220 kDa protein was purified from squid optic lobe, using a biochemical protocol designed to isolate myosins. Peptide sequence analysis, followed by cloning and sequencing of the full-length cDNA, identified this ∼220 kDa protein as a nonmuscle myosin II. This myosin is also present in axoplasm, as determined by two independent criteria. First, RT-PCR using sequence-specific primers detected the transcript in the stellate ganglion, which contains the cell bodies that give rise to the giant axon. Second, Western blot analysis using nonmuscle myosin II isotype-specific antibodies detected a single ∼220 kDa band in axoplasm. Axoplasm was fractionated through a four-step sucrose gradient after 0.6 M KI treatment, which separates organelles from cytoskeletal components. Of the total nonmuscle myosin II in axoplasm, 43.2% copurified with organelles in the 15% sucrose fraction, while the remainder (56.8%) was soluble and found in the supernatant. This myosin decorates the cytoplasmic surface of 21% of the axoplasmic organelles, as demonstrated by immunogold electron-microscopy. Thus, nonmuscle myosin II is synthesized in the cell bodies of the giant axon, is present in the axon, and is associated with isolated axoplasmic organelles. Therefore, in addition to myosin V, this myosin is likely to be an axoplasmic organelle motor