Increase of Sales Efficiency Using Multimedia Technology

Tato bakalářská práce je zaměřena na multimediální reklamní techniky, zhodnocení jejich účinnosti i finanční náročnosti. Jsou zde uvedeny důležité aspekty, kterými je třeba se řídit při působení na potenciálního zákazníka. V práci je provedeno zhodnocení dosavadní reklamy Westernového městečka s.r.o. u Boskovic a navržena reklama pomocí videoprezentací. Jsou zde uvedeny příklady vybraných firem, které nabízejí reklamu pomocí LED obrazovek na frekventovaných místech v Brně. Jsou analyzovány ekonomické aspekty a prognózy návratnosti či zisku. V práci je přiložena videoprezentace pro reklamu tohoto zábavného parku vytvořená v programu iMovie.This work is aimed at multimedia advertising techniques, evaluating their efficiency and financial performance. Important aspects are listed to be followed when exposed to a potentialcustomer. The work is an assessment of the current advertising for the Western Town s.r.o. near Boskovice and advertising by a video presentation. There are examples of selected companies that offering advertising using LED screens in busy places in Brno. Economic aspects are analyzed and forecasts of return or profit. The work is accompanied by a video presentation of advertising in this amusement park created in iMovie.

Antimicrobial Modifications of Polymers

This chapter is focused on antimicrobial modifications of polymer materials intended for medical devices production. Firstly, a brief introduction into the field of medical application of polymers is presented. Considering the fact that polymer medical devices are often connected with occurrence of nosocomial infections, the next part refers to this phenomenon and its causes. One of the possibilities of reducing of the infection occurrence is aimed at polymer modification. It is a key topic of the third part of the chapter. Finally, the methodology of the polymer materials antimicrobial properties determination is shown, together with references to the relevant standards.P(ED2.1.00/03.0111

Electrospinning of biodegradable polyester urethane: Effect of polymer-solution conductivity

This work deals with an investigation of fabrications of nanofibres based on biodegradable polylactic-acid/polyethylene-glycolchain- linked copolymers, using the electrospinning technique. Crucial attention is paid to describing the effect of polymer-solution conductivity on the morphology of the resulting nanofibres. Nanofibre systems were studied with scanning electron microscopy and the subsequent image analysis of nanofibre diameters. Hydrolytical degradability of the investigated copolymers was studied using gel permeation chromatography. The results show a significant effect of polymer-solution conductivity on the quality of nanofibres.Czech Science Foundation [15-08287Y]; Ministry of Education, Youth and Sports of the Czech Republic [LO1504]; Internal Grant Agency of TBU in Zlin [IGA/CPS/2015/003

Degradation behaviour of PLA-based polyesterurethanes under abiotic and biotic environments

Study was conducted on the degradation of polyurethanes based on Poly(lactic acid)/Poly(ethylene glycol), containing three differing concentrations of di-isocyanate compound, under three conditions (hydrolytic, thermal and composting). In the hydrolysis study, the effect of temperature and time were studied by techniques including weighting and GPC. Thermal decomposition was examined by thermogravimetry and mass spectroscopy. Composting was performed under standardized conditions and the amount of CO2 was measured. It was found that hydrolysis of the material started almost immediately after exposure to a water environment at both investigated temperatures (37°C and 55°C), whereas weight loss exhibited a certain delay. Thermal decomposition of the studied materials started below 230°C and lactide was identified as the main product. A biodegradation experiment showed that all the investigated samples successfully (>80%) mineralized within 90 days under composting conditions. © 2016 Elsevier Ltd. All rights reserved.LO1504, MEYS, Ministry of Education, Youth and SportsMinistry of Education, Youth and Sports of the Czech Republic, under the NPU I programme [LO1504

Characterization of structural and physical properties of dichloromethane= and methanol-fractionated Kraft lignin and its adsorption capacity of Cu (II) and Ni (II) ions

This work investigates the effect of the molecular weight and polydispersity of Kraft lignin(KL) on its capacity to remove copper and nickel ions from aqueous solutions. KL and its fractions were characterized by gel permeation chromatography, H-1 NMR, P-31 NMR and attenuated total reflectanceFourier transform infrared spectroscopy, elemental and ash analyses. Moreover, the glass transition temperature of lignin samples was determined by dynamic mechanical analysis. The fractionated lignin exhibited lower molecular weight and narrower polydispersity than the original KL. Accordingly, the successive solvent extraction herein applied would appear to be a convenient way to extract low molecular fractions admixed with sulphur from KL. A pseudo-second-order rate model was utilized to describe the sorption kinetics of metal ions. The KL fractionated with dichloromethane and methanol possessed a greater capacity for copper and nickel sorption than the original KL. Maximum uptake was 5.94mg of copper and 7.95mg of nickel per gram of the fractionated KL. The results obtained demonstrate that molecular weight characteristics can influence the metal scavenging efficiency of the KL.European Regional Development Fund (ERDF) through project: Future InnovationRegional Competitiveness Styria; European Regional Development Fund (ERDF) through Project-DMA analyser (Federal Ministry of Economy, Family and Youth and the National Foundation for Research, Technology and Development, Austria); Austrian Agency for International Cooperation in Education and Research (OeAD-GmbH) [CZ 06/2013]; Operational Programme Research and Development [CZ.1.05/2.1.00/03.0111]; Ministry of Education, Youth and Sports of the Czech Republic [LE12002, AMB13AT024

Carbodiimide additive to control hydrolytic stability and biodegradability of PLA

Enhanced durability of bio-based polylactic acid (PLA) is one of the prerequisites to be a considered as alternative to petroleum-based polymers in long time application. The effect of bis(2,6-diisopropylphenyl)carbodiimide (BDICDI) additive in various concentration on the extent of hydrolytic stabilization and subsequent degradation kinetics of PLA was studied in the process of abiotic hydrolysis and microbial decomposition under composting conditions. The study showed that BDICDI acts as an efficient stabilizer suppressing the hydrolytic scission of ester bonds of PLA in both degradation processes tested, especially at concentrations above 1.5% w/w. Within the stabilization period which strongly depends on concentrations of BDICDI, suppression of hydrolytic degradation also triggered preservation of thermal and mechanical properties. After the period of stabilization as the dose of stabilizer is depleted, probably via reaction with water molecules and carboxylic groups, the material was hydrolyzed at a comparable or even slightly higher rate than pure PLA. By applying the appropriate amount of BDICDI, the approximate duration of stabilization could be set to suit the desired requirements of the final product. © 2016 Elsevier Ltd15-08287Y, GACR, Czech Science FoundationCzech Science Foundation [15-08287Y]; Ministry of Education, Youth and Sports of the Czech Republic [LO1504]; Internal Grant Agency of the Tomas Bata University in Zlin [IGA/CPS/2016/004

Antimicrobial modification of polypropylene with silver nanoparticles immobilized on zinc stearate

The microwave synthesis of Ag nanoparticles on zinc stearate (ZnSt/Ag) was performed to obtain an antimicrobial additive for a polypropylene matrix. Thermoplastically prepared polymer composites contained (1, 3, 5 and 10) % of mass fractions of ZnSt/Ag. The effect of the presence of additives on the morphology and mechanical properties of composites was studied by scanning electron microscopy and stress-strain analysis. The antimicrobial activity of the composites was studied according to the ISO 22196 standard. The results showed that sufficient antimicrobial activity of the composites against both Gram-positive and Gram-negative bacterial strains was observed in the case of the composites with the highest filling studied.grant of Technology Agency of the Czech Republic [TE02000006]; Ministry of Education, Youth and Sports of the Czech Republic - Program NPU I [LO1504]; Internal Grant Agency of the Tomas Bata University in Zlin [IGA/CPS/2015/004

Enhancement of temozolomide stability by loading in chitosan-carboxylated polylactide-based nanoparticles

In the presented work, amphiphilic nanoparticles based on chitosan and carboxy-enriched polylactic acid have been prepared to improve the stability of the pro-drug temozolomide in physiological media by encapsulation. The carrier, with a diameter in the range of 150–180 nm, was able to accommodate up to 800 μg of temozolomide per mg of polymer. The obtained formulation showed good stability in physiological condition and preparation media up to 1 month. Temozolomide loaded inside the carrier exhibited greater stability than the free drug, in particular in simulated physiological solution at pH 7.4 where the hydrolysis in the inactive metabolite was clearly delayed. CS-SPLA nanoparticles demonstrated a pH-dependent TMZ release kinetics with the opportunity to increase or decrease the rate. Mass spectroscopy, UV-Vis analysis, and in vitro cell tests confirmed the improvement in temozolomide stability and effectiveness when loaded into the polymeric carrier, in comparison with the free drug. © 2017, The Author(s).15-08287Y, GACR, Grantová Agentura České Republiky; 15-08287Y, GAČR, Grantová Agentura České Republiky; CZ.1.05/2.1.00/19.0409, MŠMT, Ministerstvo Školství, Mládeže a Tělovýchovy; LO1504, MŠMT, Ministerstvo Školství, Mládeže a TělovýchovyCzech Science Foundation [15-08287Y]; Ministry of Education, Youth and Sports of the Czech Republic [LO1504, CZ.1.05/2.1.00/19.0409]; Internal Grant Agency of the Tomas Bata University in Zlin [IGA/CPS/2016/004

Thermal stability of bacteriocin nisin in polylactide-based films

This work investigates the thermal stability of bacteriocin nisin in polylactide (PLA) and polylactide/polyethylene glycol (PLA/PEG) blends at temperatures of 90 °C–180 °C. The samples were prepared by solvent cast technique and characterized according to their mechanical and thermal properties. Research on the thermal stability of nisin in the PLA and PLA/PEG systems was carried out by exposing the given films to various temperatures (90 °C, 120 °C, 160 °C, and 180 °C) for a duration of up to 48 h. Assessment of the antibacterial activity of the samples was carried out by the agar diffusion method against Micrococcus luteus, while structural analysis involved the use of high-performance liquid chromatography with mass detection. Structural changes in the polymer matrix were evaluated by gel permeation chromatography and scanning electron microscopy. The results showed that nisin retained almost 70% of its antimicrobial activity in the PLA matrix, even after treatment at 160 °C for 15 min. The presence of PEG significantly enhanced the degradation of nisin above 120 °C. © 2018 The AuthorsMinistry of Agriculture of the Czech Republic [QJ1310254]; Ministry of Education, Youth and Sports of the Czech Republic [LO1504]; Internal Grant Agency of Tomas Bata University in Zlin [IGA/CPS/2018/003

Nanoparticles based on star-shaped carboxy-terminated polylactide and chitosan for controlled release applications

In this work chitosan based nanoparticles were prepared and modified by a star-shaped carboxy-terminated polylactide (S-PLA) in order to reduce the doxorubicin burst effect in physiological solution. S-PLA was prepared by polycondensation reaction using pentetic acid as a core molecule and methansulfonic acid as catalyst and linked to chitosan backbone through coupling reaction. Afterwards, chitosan-(S-PLA) modified nanoparticles loaded with doxorubicin were prepared by polyelectrolytes complexation method using dextran sulphate sodium salt as polyanion. Results show nanoparticles with diameter in the range 100-200 nm, spherical shape and ζ-potential between 27-35 mV. The presence of (S-PLA) side chain does not influence the encapsulation efficiency of the drug but strongly reduce the initial burst effect compared with unmodified chitosan.15-08287Y, GACR, Czech Science Foundatio