Orta yaş sedanter kadınlarda sekiz haftalık step-aerobik egzersizinin bazı fiziksel uygunluk parametrelerine etkilerinin değerlendirilmesi

This study was conducted to evaluation of the effect of eight-week step-aerobic exercise program on some fitness parameters at middle-aged sedentary women. Subjects consist of 15 voluntary-healthy sedentary women mean aged 39,33±4,67 years. A step-aerobic program of three times a week, each of which lasted 45-55 minutes, was performed by the subjects throughout eight week. The intensity of the exercise was determined a 50-60% of maximum heart rate. Body weights, body mass index, heart rate during rest, heart rate after a five-minute treadmill, flexibilities, anaerobic power, aerobic capacities, back-leg strengths, right-left hand grip strengths, body fat rates, systolic and diastolic blood pressures of the subjects were measured before and after the exercise program. Statistical analysis of the data was carried out with Paired t-test. At the end of the study, a significant decrease was determined in the heart rate during rest, and after a five-minute treadmill, body fat rates and systolic blood pressures of the subjects. A significant increase was determined in the flexibility, anaerobic power, aerobic capacities, leg strengths right and left hand grip strengths of the subjects.Consequently, it was found out that an exercise which is done properly and throughout a long period has positive effects on fitness parameters of middle aged femalesOrta yaş sedanter bayanlara 8 haftalık step-aerobik egzersiz programının bazı fiziksel uygunluk parametrelerine etkisini incelemek amacı ile yapılan çalışmaya yaş ortalamaları 39,33±4,67 yıl olan sağlıklı 15 bayan, gönüllü olarak katılmıştır.             Araştırma grubuna haftada 3 gün 45–55 dakika süreli, %50–60 şiddetinde step-aerobik egzersiz programı uygulandı. Katılımcıların, egzersiz programı öncesi ve sonrası, vücut ağırlıkları, vücut kitle indeksleri, istirahat durumundaki nabızları, beş dakika yürüyüş bandı sonrası nabızları, esneklikleri, anaerobik güçleri, aerobik kapasiteleri, sırt-bacak kuvvetleri, el kavrama kuvvetleri, vücut yağ yüzdeleri, sistolik ve diastolik kan basınçları ölçüldü. Verilerin istatistiksel analizi paired t-testi ile yapıldı. Çalışma sonunda araştırma grubunun istirahat durumundaki nabızları, beş dakika yürüyüş bandı sonrası nabızları, vücut yağ yüzdeleri, sistolik kan basınçları değerlerinde anlamlı bir azalma tespit edilirken esneklik, anaerobik güç, aerobik kapasite, bacak kuvveti, sağ ve sol kavrama kuvveti değerlerinde anlamlı bir artış, tespit edilmiştir.             Sonuç olarak düzenli ve uzun süreli yapılan step-aerobik egzersizin orta yaş sedanter bayanlarda fiziksel uygunluk parametrelerine pozitif etkileri olduğu tespit edilmiştir

The effect of eight-week step-aerobic exercise program on ventilation parameters at middle aged sedentary women

Bu çalışma orta yaş sedanter bayanlarda 8 haftalık step-aerobik egzersiz programının solunum parametrelerine etkisini incelemek amacı ile yapılmıştır. Denekler yaş ortalamaları 39,33±4,67 yıl olan 15 gönüllü ve sağlıklı sedanter bayandan oluşturuldu. Deneklerin üçü günde iki paket sigara tüketmekte olup, altısı pasif içici ve diğer altı deneğin herhangi bir kötü alışkanlığı bulunmamaktadır. Araştırma grubuna haftada 3 gün 45–55 dakika süreli, %50–60 yüklenme şiddetinde step-aerobik egzersiz programı uygulandı. Araştırma grubuna egzersiz programı öncesi ve sonrası PEmax ve PImax kuvvetleri ile FVC, FEV1 ve PEF değerleri ölçüldü. Verilerin istatistiksel analizleri paried t-testi ile yapıldı. Çalışma sonunda araştırma grubunun FVC değerlerinde p<0,01 düzeyinde anlamlı bir artış, FEV1’de p<0,05 düzeyinde artış tespit edildi. Sonuç olarak düzenli ve 8 hafta süre ile yapılan step-aerobik egzersizin orta yaş sedanter bayanlarda solunum parametrelerine pozitif etkileri olduğu tespit edildi. Bu nedenle bu tip step-aerobik antrenmanlarının fiziksel uygunluk düzeyinin ve solunum fonksiyonlarının iyileştirilmesi açısından etkili olduğu söylenebilir.This study is conducted to assess the effect of eight-week step-aerobic exercise program on respiration parameters at middle-aged sedentary women. Subjects consist of 15 voluntary-healthy sedentary females mean aged 39,33&plusmn;4,67 years. Three of the subjects consume two packs of cigarettes a day, and of six the subjects, passive smokers and the other does not have any bad habits. A step-aerobic program of three sessions per week, each of which lasted 45-55 minutes, was performed by the subjects. The intensity of the exercise was determined as a 50-60% of maximum heart rate. PEmax and PImax strengths, FVC, FEV1 and PEF values of the subjects were measured before and after the exercise program. Statistical analysis of the data was done with Paired t-test. At the end of the study, a significant increase at p&lt;0,01 level was detected in FVC values of the subjects, and an increase at p&lt;0,05 level was detected in their FEV1 values. As a result, it was found that an exercise which is done regularly and for a long period of time has positive effects on fitness parameters of middle aged females. For this reason, it can be mentioned that this type of step-aerobic exercises has an important role in improving fitness parameters and functions of respiration

Re-examining the characteristics of pediatric multiple sclerosis in the era of antibody-associated demyelinating syndromes.

Background: The discovery of anti-myelin oligodendrocyte glycoprotein (MOG)-IgG and anti-aquaporin 4 (AQP4)-IgG and the observation on certain patients previously diagnosed with multiple sclerosis (MS) actually have an antibody-mediated disease mandated re-evaluation of pediatric MS series. Aim: To describe the characteristics of recent pediatric MS cases by age groups and compare with the cohort established before 2015. Method: Data of pediatric MS patients diagnosed between 2015 and 2021 were collected from 44 pediatric neurology centers across Turkiye. Clinical and paraclinical features were compared between patients with dis-ease onset before 12 years (earlier onset) and >= 12 years (later onset) as well as between our current (2015-2021) and previous (< 2015) cohorts. Results: A total of 634 children (456 girls) were enrolled, 89 (14%) were of earlier onset. The earlier-onset group had lower female/male ratio, more frequent initial diagnosis of acute disseminated encephalomyelitis (ADEM), more frequent brainstem symptoms, longer interval between the first two attacks, less frequent spinal cord involvement on magnetic resonance imaging (MRI), and lower prevalence of cerebrospinal fluid (CSF)-restricted oligoclonal bands (OCBs). The earlier-onset group was less likely to respond to initial disease-modifying treatments. Compared to our previous cohort, the current series had fewer patients with onset < 12 years, initial presentation with ADEM-like features, brainstem or cerebellar symptoms, seizures, and spinal lesions on MRI. The female/male ratio, the frequency of sensorial symptoms, and CSF-restricted OCBs were higher than reported in our previous cohort. Conclusion: Pediatric MS starting before 12 years was less common than reported previously, likely due to exclusion of patients with antibody-mediated diseases. The results underline the importance of antibody testing and indicate pediatric MS may be a more homogeneous disorder and more similar to adult-onset MS than previously thought