1,724 research outputs found
Calculation of the Phase Behavior of Lipids
The self-assembly of monoacyl lipids in solution is studied employing a model
in which the lipid's hydrocarbon tail is described within the Rotational
Isomeric State framework and is attached to a simple hydrophilic head.
Mean-field theory is employed, and the necessary partition function of a single
lipid is obtained via a partial enumeration over a large sample of molecular
conformations. The influence of the lipid architecture on the transition
between the lamellar and inverted-hexagonal phases is calculated, and
qualitative agreement with experiment is found.Comment: to appear in Phys.Rev.
Spin- and angle-resolved photoemission studies of the electronic structure of Si(110)"16x2" surfaces
The electronic structure of Si(110)"16 x 2" double-domain, single-domain and
1 x 1 surfaces have been investigated using spin- and angle-resolved
photoemission at sample temperatures of 77 K and 300 K. Angle-resolved
photoemission was conducted using horizontally- and vertically-polarised 60 eV
and 80 eV photons. Band-dispersion maps revealed four surface states ( to
) which were assigned to silicon dangling bonds on the basis of measured
binding energies and photoemission intensity changes between horizontal and
vertical light polarisations. Three surface states (, and ),
observed in the Si(110)"16 x 2" reconstruction, were assigned to Si adatoms and
Si atoms present at the edges of the corrugated terrace structure. Only one of
the four surface states, , was observed in both the Si(110)"16 x 2" and 1
x 1 band maps and consequently attributed to the pervasive Si zigzag chains
that are components of both the Si(110)"16 x 2" and 1 x 1 surfaces. A state in
the bulk-band region was attributed to an in-plane bond. All data were
consistent with the adatom-buckling model of the Si(110)"16 x 2" surface.
Whilst room temperature measurements of and were statistically
compatible with zero, measurements of the enantiomorphic A-type and
B-type Si(110)"16 x 2" surfaces gave small average polarisations of around
1.5\% that were opposite in sign. Further measurements at 77 K on A-type
Si(110)"16 x 2" surface gave a smaller value of +0.3\%. An upper limit of
may thus be taken for the longitudinal polarisation.Comment: Main paper: 12 pages and 11 figures. Supplemental information: 5
pages and 2 figure
Capitals and commitment. The case of a local learning and employment network.
This article draws on research undertaken with a Local Learning and Employment Network (LLEN) in the state of Victoria, Australia. LLEN are networks that were implemented by the state government in 2001 to undertake community capacity building through which the outcomes of young people aged 15-19 in education, training and employment would be enhanced. In 2008, in the context
of an enhanced federal commitment to social inclusion through ‘joining-up’, the Victorian experience provides insights on the implications of such policy initiatives. Drawing on Bourdieu’s discussion of the forms of capital and
Granovetter’s notion of the strength of weak ties, I argue that stores of economic, cultural and social capital as outlined by Bourdieu were necessary, but insufficient, for LLEN to achieve the objectives with which they were charged
given the failure of government to follow through on the implications of its policies. I argue for a commitment on the part of all stakeholders to realise the potential of ‘joining-up’
Pressure Induced Hydration Dynamics of Membranes
Pressure-jump initiated time-resolved x-ray diffraction studies of dynamics
of the hydration of the hexagonal phase in biological membranes show that (i)
the relaxation of the unit cell spacing is non-exponential in time; (ii) the
Bragg peaks shift smoothly to their final positions without significant
broadening or loss in crystalline order. This suggests that the hydration is
not diffusion limited but occurs via a rather homogeneous swelling of the whole
lattice, described by power law kinetics with an exponent .Comment: REVTEX 3, 10 pages,3 figures(available on request),#
Tradeoffs in jet inlet design: a historical perspective
The design of the inlet(s) is one of the most demanding tasks of the development process of any gas turbine-powered aircraft. This is mainly due to the multi-objective and multidisciplinary nature of the exercise. The solution is generally a compromise between a number of conflicting goals and these conflicts are the subject of the present paper. We look into how these design tradeoffs have been reflected in the actual inlet designs over the years and how the emphasis has shifted from one driver to another. We also review some of the relevant developments of the jet age in aerodynamics and design and manufacturing technology and we examine how they have influenced and informed inlet design decision
Surface nanobubbles as a function of gas type
We experimentally investigate the nucleation of surface nanobubbles on
PFDTS-coated silicon as a function of the specific gas dissolved in the water.
In each case we restrict ourselves to equilibrium conditions (,
). Not only is nanobubble nucleation a strong
function of gas type, but there also exists an optimal system temperature of
where nucleation is maximized, which is weakly
dependent on gas type. We also find that contact angle is a function of
nanobubble radius of curvature for all gas types investigated. Fitting this
data allows us to describe a line tension which is dependent on the type of
gas, indicating that the nanobubbles are sat on top of adsorbed gas molecules.
The average line tension was
Single-Nucleotide Polymorphisms and Markers of Oxidative Stress in Healthy Women
Purpose There is accumulating evidence that oxidative stress is an important contributor to carcinogenesis. We hypothesized that genetic variation in genes involved in maintaining antioxidant/ oxidant balance would be associated with overall oxidative stress.
Methods We examined associations between single nucleotide polymorphisms (SNPs) in MnSOD, GSTP1, GSTM1, GPX1, GPX3, and CAT genes and thiobarbituric acid-reactive substances (TBARS), a blood biomarker of oxidative damage, in healthy white women randomly selected from Western New York (n = 1402). We used general linear models to calculate age-adjusted geometric means of TBARS across the variants. We also examined the associations within strata of menopausal status.
Results For MnSOD, being heterozygous was associated with lower geometric means of TBARS (less oxidative stress), 1.28 mg/dL, compared to homozygous T-allele or homozygous Callele, 1.35 mg/dL, and 1.31 mg/dL correspondingly (p for trend = 0.01). This difference remained among postmenopausal women, 1.40 mg/dL for TT, 1.32 mg/dL for TC, and 1.34mg/dL for CC (p for trend 0.015); it was attenuated among premenopausal women. SNPs in the other genes examined (GSTP1, GSTM1, GPX1, GPX3, and CAT) were not associated with TBARS.
Conclusions Our findings suggest that genetic variation in MnSOD gene may be associated with oxidative status, particularly among postmenopausal women
Circulating markers of arterial thrombosis and late-stage age-related macular degeneration: a case-control study.
PURPOSE: The aim of this study was to examine the relation of late-stage age-related macular degeneration (AMD) with markers of systemic atherothrombosis. METHODS: A hospital-based case-control study of AMD was undertaken in London, UK. Cases of AMD (n=81) and controls (n=77) were group matched for age and sex. Standard protocols were used for colour fundus photography and to classify AMD; physical examination included height, weight, history of or treatment for vascular-related diseases and smoking status. Blood samples were taken for measurement of fibrinogen, factor VIIc (FVIIc), factor VIIIc, prothrombin fragment F1.2 (F1.2), tissue plasminogen activator, and von Willebrand factor. Odds ratios from logistic regression analyses of each atherothrombotic marker with AMD were adjusted for age, sex, and established cardiovascular disease risk factors, including smoking, blood pressure, body mass index, and total cholesterol. RESULTS: After adjustment FVIIc and possibly F1.2 were inversely associated with the risk of AMD; per 1 standard deviation increase in these markers the odds ratio were, respectively, 0.62 (95% confidence interval 0.40, 0.95) and 0.71 (0.46, 1.09). None of the other atherothrombotic risk factors appeared to be related to AMD status. There was weak evidence that aspirin is associated with a lower risk of AMD. CONCLUSIONS: This study does not provide strong evidence of associations between AMD and systematic markers of arterial thrombosis, but the potential effects of FVIIc, and F1.2 are worthy of further investigation
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