OPserver: interactive online-computations of opacities and radiative accelerations

Codes to compute mean opacities and radiative accelerations for arbitrary chemical mixtures using the Opacity Project recently revised data have been restructured in a client--server architecture and transcribed as a subroutine library. This implementation increases efficiency in stellar modelling where element stratification due to diffusion processes is depth dependent, and thus requires repeated fast opacity reestimates. Three user modes are provided to fit different computing environments, namely a web browser, a local workstation and a distributed grid.Comment: 5 pages, 1 figur

Closed-form solutions of the Schroedinger equation for a class of smoothed Coulomb potentials

An infinite family of closed-form solutions is exhibited for the Schroedinger equation for the potential $V(r) = -Z/\sqrt{|r|^{2} + a^{2}}$. Evidence is presented for an approximate dynamical symmetry for large values of the angular momentum $l$.Comment: 13 pages LaTeX, uses included Institute of Physics style files, 3 PostScript figures. In press at J. Phys. B: At. Mol. Opt. Phys. (1997

Restrictive antibiotic stewardship associated with reduced hospital mortality in gram-negative infection

Introduction: Antimicrobial stewardship has an important role in the control of Clostridium difficile infection (CDI) and antibiotic resistance. An important component of UK stewardship interventions is the restriction of broad-spectrum beta-lactam antibiotics and promotion of agents associated with a lower risk of CDI such as gentamicin. Whilst the introduction of restrictive antibiotic guidance has been associated with improvements in CDI and antimicrobial resistance evidence of the effect on outcome following severe infection is lacking. Methods: In 2008, Glasgow hospitals introduced a restrictive antibiotic guideline. A retrospective before/after study assessed outcome following gram-negative bacteraemia in the 2-year period around implementation. Results: Introduction of restrictive antibiotic guidelines was associated with a reduction in utilisation of ceftriaxone and co-amoxiclav and an increase in amoxicillin and gentamicin. 1593 episodes of bacteraemia were included in the study. The mortality over 1 year following gram-negative bacteraemia was lower in the period following guideline implementation (RR 0.852, P = 0.045). There was no evidence of a difference in secondary outcomes including ITU admission, length of stay, readmission, recurrence of bacteraemia and need for renal replacement therapy. There was a fall in CDI (RR 0.571, P = 0.014) and a reduction in bacterial resistance to ceftriaxone and co-amoxiclav but no evidence of an increase in gentamicin resistance after guideline implementation. Conclusion: Restrictive antibiotic guidelines were associated with a reduction in CDI and bacterial resistance but no evidence of adverse outcomes following gram-negative bacteraemia. There was a small reduction in one year mortality

Risk factors for failure of outpatient parenteral antibiotic therapy (OPAT) in infective endocarditis

Objectives: To identify risk factors for failure of outpatient antibiotic therapy (OPAT) in infective endocarditis (IE). Patients and methods: We identified IE cases managed at a single centre over 12 years from a prospectively maintained database. ‘OPAT failure’ was defined as unplanned readmission or antibiotic switch due to adverse drug reaction or antibiotic resistance. We analysed patient and disease-related risk factors for OPAT failure by univariate and multivariate logistic regression. We also retrospectively collected follow-up data on adverse disease outcome (defined as IE-related death or relapse) and performed Kaplan–Meier survival analysis up to 36 months following OPAT. Results: We identified 80 episodes of OPAT in IE. Failure occurred in 25/80 episodes (31.3%). On multivariate analysis, cardiac or renal failure [pooled OR 7.39 (95% CI 1.84–29.66), P = 0.005] and teicoplanin therapy [OR 8.69 (95% CI 2.01–37.47), P = 0.004] were independently associated with increased OPAT failure. OPAT failure with teicoplanin occurred despite therapeutic plasma levels. OPAT failure predicted adverse disease outcome up to 36 months (P = 0.016 log-rank test). Conclusions: These data caution against selecting patients with endocarditis for OPAT in the presence of cardiac or renal failure and suggest teicoplanin therapy may be associated with suboptimal OPAT outcomes. Alternative regimens to teicoplanin in the OPAT setting should be further investigated

The Ha Luminosity Function and Star Formation Rate at z\sim 0.2

We have measured the Ha+[N II] fluxes of the I-selected Canada-France Redshift Survey (CFRS) galaxies lying at a redshift z below 0.3, and hence derived the Ha luminosity function. The magnitude limits of the CFRS mean that only the galaxies with M(B) > -21 mag were observed at these redshifts. We obtained a total Ha luminosity density of at least 10^{39.44\pm 0.04} erg/s/Mpc^{3} at a mean z=0.2 for galaxies with rest-fame EW(Ha+[N II]) > 10 Angs. This is twice the value found in the local universe by Gallego et al. 1995. Our Ha star formation rate, derived from Madau (1997) is higher than the UV observations at same z, implying a UV dust extinction of about 1 mag. We found a strong correlation between the Ha luminosity and the absolute magnitude in the B-band: M(B(AB)) = 46.7 - 1.6 log L(Ha). This work will serve as a basis of future studies of Ha luminosity distributions measured from optically-selected spectroscopic surveys of the distant universe, and it will provide a better understanding of the physical processes responsible for the observed galaxy evolution.Comment: Accepted for publication in ApJ, 14 pages, LaTeX (macro aas2pp4.sty), 6 figure

Direct observations of a complex coronal web driving highly structured slow solar wind

The solar wind consists of continuous streams of charged particles that escape into the heliosphere from the Sun, and is split into fast and slow components, with the fast wind emerging from the interiors of coronal holes. Near the ecliptic plane, the fast wind from low-latitude coronal holes is interspersed with a highly structured slow solar wind, the source regions and drivers of which are poorly understood. Here we report extreme-ultraviolet observations that reveal a spatially complex web of magnetized plasma structures that persistently interact and reconnect in the middle corona. Coronagraphic white-light images show concurrent emergence of slow wind streams over these coronal web structures. With advanced global MHD coronal models, we demonstrate that the observed coronal web is a direct imprint of the magnetic separatrix web (S-web). By revealing a highly dynamic portion of the S-web, our observations open a window into important middle-coronal processes that appear to play a key role in driving the structured slow solar wind.Comment: This version of the article has been accepted for publication, after peer review but is not the Version of Record and does not reflect post-acceptance improvements, or any corrections. The Version of Record is available online at: http://dx.doi.org/10.1038/s41550-022-01834-

New HST Observations of the Halo Gas of NGC 3067: Limits on the Extragalactic Ionizing Background at Low Redshift and the Lyman Continuum Escape Fraction

We present UV spectroscopy from HST/GHRS and reanalyze existing H_alpha images of the quasar/galaxy pair 3C 232/NGC 3067 and of the halo gas associated with NGC 3067. The spectra permit measurement of, or limits on, the column densities of Fe I, Fe II, Mg I, and Mg II in the absorbing cloud. Two distinct models of the extragalactic radiation field are considered: (1) the ionizing spectrum is dominated by a power-law extragalactic continuum, and (2) the power-law spectrum contains a Lyman break, implying enhanced flux longward of 912 A relative to the hydrogen-ionizing flux. The H_alpha images constrain the escape fraction of Lyman continuum photons from the galaxy to f_esc <= 0.02. With the assumption that the cloud is shielded from all galactic contributions, we can constrain the intensity and shape of the extragalactic continuum. For an AGN-dominated power-law extragalactic spectrum, we derive a limit on the extragalactic ionizing flux Phi_ion >= 2600 photons cm^-2 s^-1, or I_0 >= 10^-23 erg cm^-2 s^-1 Hz^-1 sr^-1 for an ionizing spectrum with power-law index of 1.8 and a cloud of constant density. When combined with previous upper limits from the absence of H_alpha recombination emission from intergalactic clouds, our observations require 2600 <= Phi_ion <= 10000 photons cm^-2 s^-1. We show that if galactic contributions to the incident radiation are important, it is difficult to constrain Phi_ion. These results demonstrate that galactic halo opacities and their wavelength dependence are crucial to understanding the abundance of low-ionization metals in the IGM.Comment: 25 Pages LaTex, 8 PostScript Figures, accepted for publication in AJ, Nov. 99 issu

An exact universal amplitude ratio for percolation

The universal amplitude ratio $\tilde{R}_{\xi}$ for percolation in two dimensions is determined exactly using results for the dilute A model in regime 1, by way of a relationship with the q-state Potts model for q<4.Comment: 5 pages, LaTeX, submitted to J. Phys. A. One paragraph rewritten to correct error

Time delays in quasi-periodic pulsations observed during the X2.2 solar flare on 2011 February 15

We report observations of quasi-periodic pulsations (QPPs) during the X2.2 flare of 2011 February 15, observed simultaneously in several wavebands. We focus on fluctuations on time scale 1-30 s and find different time lags between different wavebands. During the impulsive phase, the Reuven Ramaty High Energy Solar Spectroscopic Imager (RHESSI) channels in the range 25-100 keV lead all the other channels. They are followed by the Nobeyama RadioPolarimeters at 9 and 17 GHz and the Extreme Ultra-Violet (EUV) channels of the Euv SpectroPhotometer (ESP) onboard the Solar Dynamic Observatory (SDO). The Zirconium and Aluminum filter channels of the Large Yield Radiometer (LYRA) onboard the Project for On-Board Autonomy (PROBA2) satellite and the SXR channel of ESP follow. The largest lags occur in observations from the Geostationary Operational Environmental Satellite (GOES), where the channel at 1-8 {\AA} leads the 0.5-4 {\AA} channel by several seconds. The time lags between the first and last channels is up to 9 s. We identified at least two distinct time intervals during the flare impulsive phase, during which the QPPs were associated with two different sources in the Nobeyama RadioHeliograph at 17 GHz. The radio as well as the hard X-ray channels showed different lags during these two intervals. To our knowledge, this is the first time that time lags are reported between EUV and SXR fluctuations on these time scales. We discuss possible emission mechanisms and interpretations, including flare electron trapping