943 research outputs found

    Enhancing Care Transitions for Older People through Interprofessional Simulation: A Mixed Method Evaluation

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    Introduction: The educational needs of the health and social care workforce for delivering effective integrated care are important. This paper reports on the development, pilot and evaluation of an interprofessional simulation course, which aimed to support integrated care models for care transitions for older people from hospital to home. Theory and methods: The course development was informed by a literature review and a scoping exercise with the health and social care workforce. The course ran six times and was attended by health and social care professionals from hospital and community (n=49). The evaluation aimed to elicit staff perceptions of their learning about care transfers of older people and to explore application of learning into practice and perceived outcomes. The study used a sequential mixed method design with questionnaires completed pre (n=44) and post (n=47) course and interviews (n=9) 2-5 months later. Results:Participants evaluated interprofessional simulation as a successful strategy. Post-course, participants identified learning points and at the interviews, similar themes with examples of application in practice were: Understanding individual needs and empathy; Communicating with patients and families; Interprofessional working; Working across settings to achieve effective care transitions. Conclusions and discussion:An interprofessional simulation course successfully brought together health and social care professionals across settings to develop integrated care skills and improve care transitions for older people with complex needs from hospital to home

    A Pingo in the Mala River Valley, Baffin Island, Northwest Territories, Canada

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    A single pingo is located on an alluvial fan within the deeply incised Mala River valley of the Borden Peninsula, Baffin Island. Its formation appears to be related to the abandonment of the river channel due to the influx of alluvium from a tributary stream.&nbsp

    Chemical Composition of Forage Plants from the Reindeer Preserve, Northwest Territories

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    Quantitative analyses of crude protein, crude fat, crude fiber, ash, calcium, phosphorus, and carotene were performed on 9 forage species, collected on 5 dates during a year. Crude protein levels were low in most forage species by mid-winter. Phosphorus levels were low in most plants throughout the year. Lichens, an important winter forage of reindeer, appear to be deficient in crude protein, calcium, phosphorus, and carotene

    A review of aflatoxin M1 in liquid milk

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    Mycotoxins continue to pose a health concern via human exposure to contaminated food. Aflatoxin M1 (AFM1), the hydroxylated metabolite of aflatoxin B1 (AFB1), may be found in the milk of dairy cattle and other mammals. In humans, AFM1 is excreted through the feces, urine, and in the case of lactating mothers, also in breast milk after consumption of aflatoxin contaminated food. Concentration of AFM1 in milk is a function of several factors, namely: animal type, milking day, milk yield, season, feeding regime, geographic, and climatic conditions. A linear relationship has been established between the amount of AFM1 in milk and the amount of AFB1 in feed consumed by animals, emphasized at first on the reduction or removal of AFB1 from feedstuffs and then elimination of AFM1 from milk. This review aims to bring up to date the current global status of AFM1 contamination of liquid milk destined for human consumption and the effects of processing and reduction methods on the elimination of aflatoxins from liquid milk

    Quantification of the Individual Characterstics of the Human Dentition: Methodology

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    This study provides a method for comparing six individual human dentition characteristics using the standard measuring tool in Adobe Photoshop CS2 as compared to measuring individual characteristics with an automated software program under development at Marquette University, which has been adapted for bitemark analysis. The algorithm identifies color-specific pixels and automatically calculates the measurements

    The Quantification of Displacement of the Anterior Teeth in the Human Dentition

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    The credibility of bite mark analysis as a forensic science is under fire in our legal system. The basis of opinions regarding the probability of a dental pattern observed in bite mark evidence matching a suspect\u27s dentition has not been objectively substantiated. Though guidelines and standards are in place, bite mark analyses have failed to provide basic scientific methods in order to be deemed of evidentiary value. Forensic scientists need to take a step back and develop valid and reliable methodologies that provide a statistical approach for defining dental characteristics in the human dentition. For this study, three computer-generated, mathematically derived curves were chosen to describe and quantify in a statistical manner the dental characteristic of displacement of eight anterior teeth in the human dentition. The Bezier, ellipse, and polynomial curves were digitally applied to scanned images from 75 dentitions comprising 150 wax exemplars of dental imprints of a male population, ages 18-44. Measurements of each tooth were made using Adobe Photoshop® software to provide maximum standardization and objectivity. Statistical tests established the best-fit-curve for determining displacement of the anterior teeth. Of the three curves, the polynomial curve had the lowest average of variance and the lowest sum of the absolute value of displacement from the curve for the anterior teeth; thus, it was shown to be the best-fit-curve based on the statistical variance for measuring displacement of the anterior teeth. Allowing for tooth displacement to be a measurable dental characteristic that can be scientifically quantified, the polynomial curve provides a valid and reliable methodology for bite mark analysis in future population studies. The polynomial curve may significantly enhance the judicial process associated with bite mark evidence by providing a scientific basis for objective interpretation of a unique dental characteristic based on an individual curve and the individuality of a bite pattern or imprint from a victim and/or suspect(s)

    Earth Hummocks in the Sunshine Area of the Rocky Mountains, Alberta and British Columbia

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    Earth hummocks were found on the Continental Divide of the Rocky Mountains in a non-permafrost environment. Many hummocks show involutions of organic layers within 25 cm of the surface, suggesting that the hummocks are still active. The soil material is a non-plastic, silt-textured volcanic ash. During brief periods in the spring the upper soil horizons can become super-saturated with water; the soil then becomes liquid, resulting in involutions in the surface layers. This mechanism is generally erosional and it is unlikely that it contributed to the formation of earth hummocks. The hummocks are believed to be relict features that were formed under colder conditions, when permafrost was likely present in the ground.Key words: Rocky Mountains, hummocks, permafrost, soil horizonsMots clés: Rocheuses, monticules, pergélisol, horizons du so

    The implications of COVID-19 for health workforce planning and policy: the case of Peru

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    Like many countries Peru is confronting uncertainties due to the COVID-19 pandemic and its consequences. This is having impacts not only on health systems but also on the planning and preparation of its workforces. In this case article we summarise the progress Peru has been making to improve its workforce capacity and planning and review how Peru has coped with the stresses put on its health system arising from the pandemic. By recounting the responses that the Ministry of Health made through mobilising existing capabilities, additional workers and collaboration with health science faculties and health professional colleges, the article identifies that a longer-term planning perspective based on skills that services require is something that Peru may consider to compliment the health workforce investments that are already being made. As such, this case provides an example for workforce planners and policy makers to contemplate when considering health workforce planning in post-COVID uncertainty

    TDP-43 Proteinopathy and ALS: Insights into Disease Mechanisms and Therapeutic Targets

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    # The Author(s) 2015. This article is published with open access at Springerlink.com Abstract Therapeutic options for patients with amyotrophic lateral sclerosis (ALS) are currently limited. However, recent studies show that almost all cases of ALS, as well as tau-negative frontotemporal dementia (FTD), share a common neuropathology characterized by the deposition of TAR-DNA binding protein (TDP)-43-positive protein inclusions, offering an attractive target for the design and testing of novel therapeutics. Here we demonstrate how diverse environmental stressors linked to stress granule formation, as well as muta-tions in genes encoding RNA processing proteins and protein degradation adaptors, initiate ALS pathogenesis via TDP-43. We review the progressive development of TDP-43 proteinopathy from cytoplasmic mislocalization and misfolding through to macroaggregation and the addition of phosphate and ubiquitin moieties. Drawing from cellular and animal studies, we explore the feasibility of therapeutics that act at each point in pathogenesis, from mitigating genetic risk using antisense oligonucleotides to modulating TDP-43 proteinopathy itself using small molecule activators of au-tophagy, the ubiquitin-proteasome system, or the chaper-one network. We present the case that preventing the misfolding of TDP-43 and/or enhancing its clearance represents the most important target for effectively treating ALS and frontotemporal dementia

    Knowledge-Related Barriers to Communication and Coordination in Disaster Response: Adelphi Study

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    Multi-organizational ad hoc knowledge networks have the potential to improve the effectiveness of disaster response and recovery by helping organizations share information, coordinate their activities and leverage participants\u27 expertise. This paper reports an exploratory study to identify the major barriers to effectiveness in ad hoc knowledge networks in disaster response. The research methodology is a multi-panel Delphi survey, with each panel comprised of experienced emergency response professionals from different types of response organizations (e.g., fire fighters, EOC (emergency operations center) directors, law enforcement professionals). The study is currently in progress, and results from the first two panels are reported
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