Alien Registration- Scott, Lydia (Baileyville, Washington County)

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University rural health clubs: nurturing the future Austalian rural workforce

CONTEXT: Australian university rural health clubs (RHC) are part of a national strategy to address the rural health workforce shortage. The student members of these clubs throughout Australia comprise the National Rural Health Network (NRHN). The NRHN is a multidisciplinary body representing medical, nursing and allied health students, aiming to increase the health workforce and health outcomes for rural and remote Australians. The NRHN and its constituent clubs run a variety of activities to promote rural careers to both school-aged and university students. These have included events at local, state and national levels. ISSUES: The purpose of the present article is to describe the roles and activities of RHC and the NRHN as they aim to contribute towards developing a sustainable rural workforce. Key features of RHC and the NRHN are: (1) providing positive rural experiences; (2) peer promotion of rural health; (3) personal and professional development; (4) providing a volunteer workforce for rural health initiatives; and (5) cross-disciplinary interaction. The NRHN is currently investigating methods to quantify the impact of the RHC on the career choices of potential rural health professionals. LESSONS LEARNED: The NRHN and its constituent clubs are student-driven initiatives occupying a unique place in addressing the rural workforce shortage. Although little formal evidence exists for their success, the issues raised in this article illustrate their importance and broader benefits in this field

Gi- and Gs-coupled GPCRs show different modes of G-protein binding.

More than two decades ago, the activation mechanism for the membrane-bound photoreceptor and prototypical G protein-coupled receptor (GPCR) rhodopsin was uncovered. Upon light-induced changes in ligand-receptor interaction, movement of specific transmembrane helices within the receptor opens a crevice at the cytoplasmic surface, allowing for coupling of heterotrimeric guanine nucleotide-binding proteins (G proteins). The general features of this activation mechanism are conserved across the GPCR superfamily. Nevertheless, GPCRs have selectivity for distinct G-protein family members, but the mechanism of selectivity remains elusive. Structures of GPCRs in complex with the stimulatory G protein, Gs, and an accessory nanobody to stabilize the complex have been reported, providing information on the intermolecular interactions. However, to reveal the structural selectivity filters, it will be necessary to determine GPCR-G protein structures involving other G-protein subtypes. In addition, it is important to obtain structures in the absence of a nanobody that may influence the structure. Here, we present a model for a rhodopsin-G protein complex derived from intermolecular distance constraints between the activated receptor and the inhibitory G protein, Gi, using electron paramagnetic resonance spectroscopy and spin-labeling methodologies. Molecular dynamics simulations demonstrated the overall stability of the modeled complex. In the rhodopsin-Gi complex, Gi engages rhodopsin in a manner distinct from previous GPCR-Gs structures, providing insight into specificity determinants

“I've seen first-hand the difference that it’s made to these children's lives”: An exploration of the use of dogs in six schools in England and Wales.

This thesis is divided into three parts: a major literature review (Part 1), an empirical research paper (Part 2) and a critical appraisal (Part 3). Part 1: Major Literature Review The literature review is comprised of two sections. Part 1a consists of a narrative review, which aims to provide the background context of the therapeutic use of animals by considering the benefits that have been observed in a wide range of settings, including health and education. Following this, Part 1b consists of a systematic review of the literature, which adopts an international perspective to explore how dogs specifically have been used in education settings across the world. Part 2: Empirical Research Paper The research paper in Part 2 details the current study which aims to explore how schools in the UK are currently using dogs to support their pupils. A questionnaire was circulated nationally to recruit schools currently implementing dog-assisted interventions to take part in semi-structured interviews to explore the types of interventions being used in more detail. The methodology, procedure and analysis of the data are presented, and implications of the findings are considered. Part 3: Critical Appraisal The critical appraisal in Part 3 provides an overview of the research process and a reflective and reflexive account of the development of both the research itself and of the researcher. Decisions made throughout the research process are considered and the implications of these discussed

Trauma-Informed Practices of Mental Health Providers Around the Globe

This study examined trauma-informed practices of mental health professionals from 25 different countries. The literature indicates that many practitioners feel unprepared and unequipped to therapeutically work with individuals who have experienced trauma-related psychological disorders (SAMHSA, 2014). This poster highlights the deficits in trauma-informed competency among practitioners from around the globe, offers recommendations to emphasize graduate and post-graduate trauma-informed training, and also offers suggestions for future trauma competencies

The History of Neurosurgical Management of Ischemic Stroke

Stroke remains a major public health issue and the second leading cause of death worldwide. The Hippocratic Corpus used the word apoplexy to describe a person collapsing while retaining pulse and respiration. This is believed to be the first written description of stroke. The theories of what caused stroke evolved over the years. When autopsies were performed stroke was attributed to emboli and thrombi formation. Carotid endarterectomies (CEA) were then performed for the treatment of stroke. Originally CEA were seen with skepticism but the North American Symptomatic Carotid Endarterectomy trial (NASCET) and the European Carotid Surgery trial (ECS) helped restore their efficacy in the management of ischemic stroke. A milestone in the management of ischemic stroke was the use of intravenous tissue plasminogen activator (tPA). Secondary to the limitations of the use of tPA other avenues were sought which included intraarterial recombinant prourokinase and mechanical thrombectomy. The field of mechanical thrombectomy continues to be rapidly changing and evolving. Various randomized controlled trials and meta-analysis have been conducted in order to evaluate who will benefit from mechanical thrombectomies, the timing, the best device to use and the role of combining this intervention with the administration of intravenous tPA

Prioritization and Planning to Improve Urban Tree Health in the Chicago Region

The Chicago Region Trees Initiative (CRTI) has collected one of the largest data sets on urban forestry in the United States. This data informs where and how CRTI prioritizes its work and capacity building. This data has been incorporated into interactive online resources that communities and neighborhoods can access to help decision makers, landowners, and managers understand where and what to plant, the value of the urban forest, impacts of woody invasive species, heat island challenges, and where opportunities exist for oak ecosystem enhancement. This data helps CRTI and its partners to prioritize action

Cross Sector Partnerships – Development of the Chicago Region Trees Initiative

The Chicago Region Trees Initiative (CRTI) is a partnership of more than 200 organizations across the seven county Chicago metro region. The CRTI believes that trees are critical to our quality of life, and its mission is to ensure that trees are more healthy, abundant, diverse, and equitably distributed to provide needed benefits to all people and communities in the Chicago region. Our key goals are to inspire people to value trees, increase the Chicago region’s tree canopy, reduce threats to trees, and enhance oak ecosystems. The CRTI has built upon the work and programs of others, and the experience of partners to shape the urban forest in the Chicago region by 2050