Stochastic resetting by a random amplitude

Stochastic resetting, a diffusive process whose amplitude is reset to the origin at random times, is a vividly studied strategy to optimize encounter dynamics, e.g., in chemical reactions. Here we generalize the resetting step by introducing a random resetting amplitude such that the diffusing particle may be only partially reset towards the trajectory origin or even overshoot the origin in a resetting step. We introduce different scenarios for the random-amplitude stochastic resetting process and discuss the resulting dynamics. Direct applications are geophysical layering (stratigraphy) and population dynamics or financial markets, as well as generic search processes.Predoc Severo Ochoa 2018 grant PRE2018-084427; DFG Grant No. ME 1535/12-

Aircraft noise effects: An inter-disciplinary study of the effect of aircraft noise on man. Part 3: Supplementary analyses of the social-scientific portion of the study on aircraft noise conducted by the DFG

Variables in a study of noise perception near the Munich-Reims airport are explained. The interactive effect of the stimulus (aircraft noise) and moderator (noise sensitivity) on the aircraft noise reaction (disturbance or annoyance) is considered. Methods employed to demonstrate that the moderator has a differencing effect on various stimulus levels are described. Results of the social-scientific portion of the aircraft noise project are compared with those of other survey studies on the problem of aircraft noise. Procedures for contrast group analysis and multiple classification analysis are examined with focus on some difficulties in their application

Subdiffusive transport in intergranular lanes on the Sun. The Leighton model revisited

In this paper we consider a random motion of magnetic bright points (MBP) associated with magnetic fields at the solar photosphere. The MBP transport in the short time range [0-20 minutes] has a subdiffusive character as the magnetic flux tends to accumulate at sinks of the flow field. Such a behavior can be rigorously described in the framework of a continuous time random walk leading to the fractional Fokker-Planck dynamics. This formalism, applied for the analysis of the solar subdiffusion of magnetic fields, generalizes the Leighton's model.Comment: 7 page

The rarefied (non-continuum) conditions of tracer particle transport in soils, with implications for assessing the intensity and depth dependence of mixing from geochronology

We formulate tracer particle transport and mixing in soils due to disturbance-driven particle motions in terms of the Fokker–Planck equation. The probabilistic basis of the formulation is suitable for rarefied particle conditions, and for parsing the mixing behavior of extensive and intensive properties belonging to the particles rather than to the bulk soil. The significance of the formulation is illustrated with the examples of vertical profiles of expected beryllium-10 (10Be) concentrations and optically stimulated luminescence (OSL) particle ages for the benchmark situation involving a one-dimensional mean upward soil motion with nominally steady surface erosion in the presence of either uniform or depth-dependent particle mixing, and varying mixing intensity. The analysis, together with Eulerian–Lagrangian numerical simulations of tracer particle motions, highlights the significance of calculating ensemble-expected values of extensive and intensive particle properties, including higher moments of particle OSL ages, rather than assuming de facto a continuum-like mixing behavior. The analysis and results offer guidance for field sampling and for describing the mixing behavior of other particle and soil properties. Profiles of expected 10Be concentrations and OSL ages systematically vary with mixing intensity as measured by a Péclet number involving the speed at which particles enter the soil, the soil thickness, and the particle diffusivity. Profiles associated with uniform mixing versus a linear decrease in mixing with depth are distinct for moderate mixing, but they become similar with either weak mixing or strong mixing; uniform profiles do not necessarily imply uniform mixing.</p

Development of a Groundwater Management Model for the Project Shoal Area

This document describes the development of a user-friendly and efficient groundwater management model of the Project Shoal Area (PSA and surrounding area that will allow the U.S. Department of Energy and State of Nevada personnel to evaluate the impact of proposed water-use scenarios. The management model consists of a simple hydrologic model within an interactive groundwater management framework. This framework is based on an object user interface that was developed by the U.S. Geological Survey and has been used by the Desert Research Institute researchers and others to couple disparate environmental resource models, manage temporal and spatial data, and evaluate model results for management decision making. This framework was modified and applied to the PSA and surrounding Fairview Basin. The utility of the management model was demonstrated through the application of hypothetical future scenarios including mineral mining, regional expansion of agriculture, and export of water to large urban areas outside the region. While the results from some of the scenarios indicated potential impacts to groundwater levels near the PSA and others did not, together they demonstrate the utility of the management tool for the evaluation of proposed changes in groundwater use in or near the PSA

Particle-in-cell Simulations of Ion Dynamics in a Pinched-beam Diode

article-in-cell simulations of a 1.6 MV, 800 kA, and 50 ns pinched-beam diode have been completed with emphasis placed on the quality of the ion beams produced. Simulations show the formation of multiple regions in the electron beam flow characterized by locally high charge and current density (“hot spots”). As ions flow through the electron-space-charge cloud, these hot spots electrostatically attract ions to produce a non-uniform ion current distribution. The length of the cavity extending beyond the anode-to-cathode gap (i.e., behind the cathode tip) influences both the number and amplitude of hot spots. A longer cavity length increases the number of hot spots yet significantly reduces the amplitude producing a smoother, more uniform ion beam than for shorter cavities. The net current and the ion bending angles are also significantly smaller with long cavities

Analysis of ancestry heterozygosity suggests that hybrid incompatibilities in threespine stickleback are environment dependent

Hybrid incompatibilities occur when interactions between opposite ancestry alleles at different loci reduce the fitness of hybrids. Most work on incompatibilities has focused on those that are “intrinsic,” meaning they affect viability and sterility in the laboratory. Theory predicts that ecological selection can also underlie hybrid incompatibilities, but tests of this hypothesis using sequence data are scarce. In this article, we compiled genetic data for F(2) hybrid crosses between divergent populations of threespine stickleback fish (Gasterosteus aculeatus L.) that were born and raised in either the field (seminatural experimental ponds) or the laboratory (aquaria). Because selection against incompatibilities results in elevated ancestry heterozygosity, we tested the prediction that ancestry heterozygosity will be higher in pond-raised fish compared to those raised in aquaria. We found that ancestry heterozygosity was elevated by approximately 3% in crosses raised in ponds compared to those raised in aquaria. Additional analyses support a phenotypic basis for incompatibility and suggest that environment-specific single-locus heterozygote advantage is not the cause of selection on ancestry heterozygosity. Our study provides evidence that, in stickleback, a coarse—albeit indirect—signal of environment-dependent hybrid incompatibility is reliably detectable and suggests that extrinsic incompatibilities can evolve before intrinsic incompatibilities

Combined In Silico, In Vivo, and In Vitro Studies Shed Insights into the Acute Inflammatory Response in Middle-Aged Mice

We combined in silico, in vivo, and in vitro studies to gain insights into age-dependent changes in acute inflammation in response to bacterial endotoxin (LPS). Time-course cytokine, chemokine, and NO2-/NO3- data from "middle-aged" (6-8 months old) C57BL/6 mice were used to re-parameterize a mechanistic mathematical model of acute inflammation originally calibrated for "young" (2-3 months old) mice. These studies suggested that macrophages from middle-aged mice are more susceptible to cell death, as well as producing higher levels of pro-inflammatory cytokines, vs. macrophages from young mice. In support of the in silico-derived hypotheses, resident peritoneal cells from endotoxemic middle-aged mice exhibited reduced viability and produced elevated levels of TNF-α, IL-6, IL-10, and KC/CXCL1 as compared to cells from young mice. Our studies demonstrate the utility of a combined in silico, in vivo, and in vitro approach to the study of acute inflammation in shock states, and suggest hypotheses with regard to the changes in the cytokine milieu that accompany aging. © 2013 Namas et al

Emergency Coronary Artery Bypass Grafting: Indications and Outcomes from 2003 through 2013

Emergency coronary artery bypass grafting (CABG) is associated with increased in-hospital mortality rates and adverse events. This study retrospectively evaluated indications and outcomes in patients who underwent emergency CABG. The Society of Thoracic Surgeons database for a single center (Jewish Hospital) was queried to identify patients undergoing isolated CABG. Univariate analysis was performed. From January 2003 through December 2013, 5,940 patients underwent CABG; 212 presented with emergency status. A high proportion of female patients (28.2%) underwent emergency surgery. Emergency CABG patients experienced high rates of intra-aortic balloon pump support, bleeding, dialysis, in-hospital death, and prolonged length of stay. The proportion of emergency coronary artery bypass grafting declined during years 2008–2013 compared with 2003–2007 (2.2% vs. 4.5%, P \u3c 0.001), but the incidence of angiographic accident (5.3% vs. 29.2%) increased as an indication. Ongoing ischemia remains the most frequent indication for emergency CABG, yet the incidence of angiographic accident has greatly increased. In-hospital mortality rates and adverse events remain high. If we look specifically at emergency CABG cases arising from angiographic accident, we find that 14 (15%) of all 93 emergency CABG deaths occurred in that subset of patients. Efforts to improve outcomes should therefore be focused on this high-risk group