Grazing Land Contributions to Carbon Sequestration

Key points 1. Grazing management can be used to increase soil organic carbon sequestration. 2. Grazing land soils contain large amounts of carbon with depth, and can store it for centuries. 3. Policies to encourage terrestrial carbon sequestration through conservation and good management of grazing lands are critical for many countries and the world

Propulsion and Space Vehicle Systems Analysis Program Tensor I, volume I Technical report no. 341

Computer program for space vehicle and propulsion systems analysi

Influence of Grazing on Soil Microbial Communities on a Mixed Grass Prairie Ecosystem

The grazing of ungulates is the predominant use for much of the world\u27s semiarid rangelands. Grazing these lands can result in significant changes not only in the vegetation community but also in the soil physical, chemical and biological properties. Changes in soil physical and chemical properties and the plant community can potentially lead to changes in soil microbial communities which may have long-term ramifications for nutrient cycling and carbon (C) sequestration. The objective of this research was to ascertain the influence of three long-term grazing treatments on soil microbial communities

Clinical and pathological outcomes of induction chemotherapy before neoadjuvant radiotherapy in locally‐advanced rectal cancer

Background and ObjectivesIn North America, preoperative combination chemoradiation is the most commonly recommended and utilized approach to locally advanced rectal cancer. There is increasing interest in the use of induction chemotherapy (IC) before radiation and surgery in locally advanced rectal cancer. How widely IC is being used and whether it improves pathologic and oncologic outcomes is unknown.MethodsWe evaluated clinical stage 2 or 3 rectal cancer patients in the National Cancer Database between 2006 and 2015. We identified predictors of use of IC with multivariable logistic regression and compared survival between groups using Cox proportional hazards regression.ResultsAmong 36 268 patients, IC use increased significantly over time from 5.5% in 2006 to 15.9% in 2015 (P < 0.001). Treatment at a hospital with a high IC rate was an independent predictor of receipt of IC. IC and traditional therapy yielded similar pathologic complete response rates (32.2% vs 30.5%, P = 0.2) and similar 5‐year survival (82.4% vs 81.4%, 0.71).ConclusionsUse of IC for locally advanced rectal cancer has increased significantly. The choice of IC seems to be driven more by institutional and regional practice patterns than clinical characteristics and is not associated with improved pathologic or oncologic outcomes.Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/150518/1/jso25474.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/150518/2/jso25474_am.pd

Subcellular sequencing of single neurons reveals the dendritic transcriptome of GABAergic interneurons

Although mRNAs are localized in the processes of excitatory neurons, it is still unclear whether interneurons also localize a large population of mRNAs. In addition, the variability in the localized mRNA population within and between cell-types is unknown. Here we describe the unbiased transcriptomic characterization of the subcellular compartments of hundreds of single neurons. We separately profiled the dendritic and somatic transcriptomes of individual rat hippocampal neurons and investigated mRNA abundances in the soma and dendrites of single glutamatergic and GABAergic neurons. We found that, like their excitatory counterparts, interneurons contain a rich repertoire of ~4000 mRNAs. We observed more cell type-specific features among somatic transcriptomes than their associated dendritic transcriptomes. Finally, using cell-type specific metabolic labelling of isolated neurites, we demonstrated that the processes of Glutamatergic and, notably, GABAergic neurons were capable of local translation, suggesting mRNA localization and local translation is a general property of neurons

Registration of ‘Haymaker’ Intermediate Wheatgrass

‘NU-ARS AC2’ crested wheatgrass [Agropyron cristatum (L.) Gaertn.–A. cristatum var. pectinatum (M. Bieb.) Tzvelev] (Reg. no. CV-28, PI 634507) is a broadly adapted, complex composite population produced by allowing selected plants from fairway-type germplasm accessions to randomly intermate. It originates from collections made by Douglas Dewey, USDA-ARS Plant Geneticist, in the former USSR in 1977. It was released in September 2002 by USDA-ARS; Agricultural Research Division, Institute of Agricultural and Natural Resources, University of Nebraska-Lincoln; and the USDA-NRCS. NU-ARS AC2 was tested under the experimental designation NE AC2

Registration of ‘NU-ARS AC2’ Crested Wheatgrass

‘NU-ARS AC2’ crested wheatgrass [Agropyron cristatum (L.) Gaertn.–A. cristatum var. pectinatum (M. Bieb.) Tzvelev] (Reg. no. CV-28, PI 634507) is a broadly adapted, complex composite population produced by allowing selected plants from fairway-type germplasm accessions to randomly intermate. It originates from collections made by Douglas Dewey, USDA-ARS Plant Geneticist, in the former USSR in 1977. It was released in September 2002 by USDA-ARS; Agricultural Research Division, Institute of Agricultural and Natural Resources, University of Nebraska-Lincoln; and the USDA-NRCS. NU-ARS AC2 was tested under the experimental designation NE AC2

Impact of Grazing Management Strategies on Carbon Sequestration in a Semi-Arid Rangeland, USA

The effects of 12 years of grazing management strategies on carbon (C) distribution and sequestration were assessed on a semi-arid mixed-grass prairie in Wyoming, USA. Five grazing treatments were evaluated: non-grazed exclosures; continuous, season-long grazing at a light (22 steer-days ha-1) stocking rate; and, rotationally-deferred, short-duration rotation, and continuous, season-long grazing, all three at a heavy stocking rate (59 steer-days ha-1). Non-grazed exclosures exhibited a large buildup of dead plant material (72% of total aboveground plant matter) and forb biomass represented a large component (35%) of the plant community. Stocking rate, but not grazing strategy, changed plant community composition and decreased surface litter. Light grazing decreased forbs and increased cool-season mid-grasses, resulting in a highly diversified plant community and the highest total production of grasses. Heavy grazing increased warm-season grasses at the expense of the cool-season grasses, which decreased total forage production and opportunity for early season grazing. Compared to the exclosures, all grazing treatments resulted in significantly higher levels of C (6000-9000 kg ha-1) in the surface 15 cm of the soil. Higher levels of soil C with grazing are likely the result of faster litter decomposition and recycling, and redistribution of C within the 0-60 cm plant-soil system. Grazing at an appropriate stocking rate had beneficial effects on plant composition, forage production, and soil C sequestration. Without grazing, deterioration of the plant-soil system is indicated

Radical Scavenging of Poly(Methyl Methacrylate) Bone Cement by Rifampin and Clinically Relevant Properties of the Rifampin-Loaded Cement

Objectives: The objective of this study was to characterize the effect of rifampin incorporation into poly(methyl methacrylate) (pMMA) bone cement. While incompatibilities between the two materials have been previously noted, we sought to identify and quantify the cause of rifampin\u27s effects, including alterations in curing properties, mechanical strength, and residual monomer content. Methods: Four cement groups were prepared using commercial pMMA bone cement: a control; one with 1 g of rifampin; and one each with equimolar amounts of ascorbic acid or hydroquinone relative to the amount of rifampin added. The handling properties, setting time, exothermic output, and monomer loss were measured throughout curing. The mechanical strength of each group was tested over 14 days. A radical scavenging assay was used to assess the scavenging abilities of rifampin and its individual moieties. Results: Compared with control, the rifampin-incorporated cement had a prolonged setting time and a reduction in exothermic output during polymerization. The rifampin cement showed significantly reduced strength and was below the orthopaedic weight-bearing threshold of 70 Mpa. Based on the radical scavenging assay and strength tests, the hydroquinone structure within rifampin was identified as the polymerization inhibitor. Conclusion: The incorporation of rifampin into pMMA bone cement interferes with the cement\u27s radical polymerization. This interference is due to the hydroquinone moiety within rifampin. This combination alters the cement\u27s handling and curing properties, and lowers the strength below the threshold for weight-bearing applications. Additionally, the incomplete polymerization leads to increased toxic monomer output, which discourages its use even in non-weight-bearing applications