996 research outputs found

    Magnetic domain-wall motion by propagating spin waves

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    We found by micromagnetic simulations that the motion of a transverse wall (TW) type domain wall in magnetic thin-film nanostripes can be manipulated via interaction with spin waves (SWs) propagating through the TW. The velocity of the TW motion can be controlled by changes of the frequency and amplitude of the propagating SWs. Moreover, the TW motion is efficiently driven by specific SW frequencies that coincide with the resonant frequencies of the local modes existing inside the TW structure. The use of propagating SWs, whose frequencies are tuned to those of the intrinsic TW modes, is an alternative approach for controlling TW motion in nanostripes

    Chronic Kidney Disease Cohort Studies: A Guide to Metabolome Analyses

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    Kidney diseases still pose one of the biggest challenges for global health, and their heterogeneity and often high comorbidity load seriously hinders the unraveling of their underlying pathomechanisms and the delivery of optimal patient care. Metabolomics, the quantitative study of small organic compounds, called metabolites, in a biological specimen, is gaining more and more importance in nephrology research. Conducting a metabolomics study in human kidney disease cohorts, however, requires thorough knowledge about the key workflow steps: study planning, sample collection, metabolomics data acquisition and preprocessing, statistical/bioinformatics data analysis, and results interpretation within a biomedical context. This review provides a guide for future metabolomics studies in human kidney disease cohorts. We will offer an overview of important a priori considerations for metabolomics cohort studies, available analytical as well as statistical/bioinformatics data analysis techniques, and subsequent interpretation of metabolic findings. We will further point out potential research questions for metabolomics studies in the context of kidney diseases and summarize the main results and data availability of important studies already conducted in this field

    Rapid non-contacting resistivity logging of core

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    We demonstrate a non-contact approach to whole-core and split-core resistivity measurements, imaging a 15 mm-thick, dipping, conductive layer, producing a continuous log of the whole core and enabling the development of a framework to allow representative plugs to be taken, for example. Applications include mapping subtle changes in grain fabric (e.g. grain shape) caused by variable sedimentation rates, for example, as well as the well-known dependencies on porosity and water saturation. The method operates at relatively low frequencies (i.e. low induction numbers), needing highly sensitive coil pairs to provide resistivity measurements at the desired resolution. A four-coil arrangement of two pairs of transmitter and receiver coils is used to stabilize the measurement. One ‘coil pair’ acts as a control, enabling the effects of local environmental variations, which can be considerable, to be removed from the measurement at source. Comparing our non-contact approach and independent traditional ‘galvanic’ resistivity measurements indicates that the non-contact measurements are directly proportional to the reciprocal of the sample resistivity (i.e. conductivity). The depth of investigation is discussed in terms of both theory and practical measurements, and the response of the technique to a variety of synthetic ‘structures’ is presented. We demonstrate the potential of the technique for rapid electrical imaging of core and present a whole-core image of a dipping layer with azimuthal discrimination at a resolution of the order of 10 mm. Consequently, the technique could be used to investigate different depths within the core, in agreement with theoretical predictions
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