5,611 research outputs found

    Correlation-Space Description of the Percolation Transition in Composite Microstructures

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    We explore the percolation threshold shift as short-range correlations are introduced and systematically varied in binary composites. Two complementary representations of the correlations are developed in terms of the distribution of phase bonds or, alternatively, using a set of appropriate short-range order parameters. In either case, systematic exploration of the correlation space reveals a boundary that separates percolating from nonpercolating structures and permits empirical equations that identify the location of the threshold for systems of arbitrary short-range correlation states. Two- and three-dimensional site lattices with two-body correlations, as well as a two-dimensional hexagonal bond network with three-body correlations, are explored. The approach presented here should be generalizable to more complex correlation states, including higher-order and longer-range correlations

    Baseline tests of the C. H. Waterman DAF electric passenger vehicle

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    An electric vehicle was tested as part of an Energy Research Development Administration (ERDA) project to characterize the state-of-the-art of electric vehicles. The Waterman vehicle performance test results are presented in this report. The vehicle is a converted four-passenger DAF 46 sedan. It is powered by sixteen 6-volt traction batteries through a three-step contactor controller actuated by a foot throttle to change the voltage applied to the 6.7 kW motor. The braking system is a conventional hydraulic braking system

    Shear transformation zone dynamics model for metallic glasses incorporating free volume as a state variable

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    A mesoscale model, shear transformation zone dynamics (STZ dynamics), is employed to investigate the connections between the structure and deformation of metallic glasses. The present STZ dynamics model is adapted to incorporate a structure-related state variable, and evolves via two competing processes: STZ activation, which creates free volume, vs. diffusive rearrangement, which annihilates it. The dynamical competition between these two processes gives rise to an equilibrium excess free volume that can be connected to flow viscosity via the phenomenological Vogel–Fulcher–Tammann relation in relaxed structures near the glass transition temperature. On the other hand, the excess free volume allows glasses to deform at low temperatures via shear localization into shear bands, even in the presence of internal stress distributions that arise upon cooling after processing.Massachusetts Institute of Technology. Institute for Soldier NanotechnologiesUnited States. Defense Threat Reduction Agency (Contract HDTRA-11-1-0062

    Hybrid Quantum Dot-2D Electron Gas Devices for Coherent Optoelectronics

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    We present an inverted GaAs 2D electron gas with self-assembled InAs quantum dots in close proximity, with the goal of combining quantum transport with quantum optics experiments. We have grown and characterized several wafers -- using transport, AFM and optics -- finding narrow-linewidth optical dots and high-mobility, single subband 2D gases. Despite being buried 500 nm below the surface, the dots are clearly visible on AFM scans, allowing precise localization and paving the way towards a hybrid quantum system integrating optical dots with surface gate-defined nanostructures in the 2D gas.Comment: 4 pages, 5 figures (color

    Cryopyrin-associated periodic fever syndrome manifesting as Tolosa-Hunt syndrome

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    Background Tolosa-Hunt syndrome (THS) is characterized by unilateral orbital pain, ipsilateral oculomotor paresis and a prompt response to treatment with corticosteroids. Several reports have demonstrated that the clinical features of THS are not specific to one causal aetiology and can lead to misdiagnosis. Case report We report the case of a patient diagnosed with THS after an episode of unilateral orbital pain and diplopia with demonstration of granulomatous inflammation of both cavernous sinus on cerebral magnetic resonance imaging and an immediate response to treatment with corticosteroids. Progression of the disease over the following years, accompanied by increasing signs of inflammation on cerebral magnetic resonance imaging and cerebrospinal fluid pleocytosis, led to further diagnostic tests. Genetic analyses revealed a heterozygote low-penetrance mutation (Q703K) of the cryopyrin/NLRP3 gene compatible with a cryopyrin-associated periodic fever syndrome. Discussion This case report demonstrates that THS can be a central nervous system manifestation of cryopyrin-associated periodic fever syndrome, which therefore represents a differential diagnosis of THS, even in elderly patients

    Percolation of diffusionally evolved two-phase systems

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    Percolation thresholds and critical exponents for universal scaling laws are computed for microstructures that derive from phase-transformation processes in two dimensions. The computed percolation threshold for nucleation and growth processes, p[subscript c] ≈0.6612, is similar to those obtained by random placement of disks and greater than that of spinodal decomposition, p[subscript c] ≈0.4987. Three critical exponents for scaling behavior were computed and do not differ significantly from universal values. The time evolution of a characteristic microstructural length was also computed: For spinodal decomposition, this length grows according to a power law after a short incubation period; for nucleation and growth, there are several transitions in the nature of the growth law. We speculate that the transitions in nucleation and growth derive from competing effects of coalescence at short times and then subsequent coarsening. Short-range order is present, but different, for both classes of microstructural evolution. © 2011 American Physical Society.National Science Foundation (U.S.) (Contract DMR-0855402

    Dynamic masses for the close PG1159 binary SDSSJ212531.92-010745.9

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    SDSSJ212531.92-010745.9 is the first known PG1159 star in a close binary with a late main sequence companion allowing a dynamical mass determination. The system shows flux variations with a peak-to-peak amplitude of about 0.7 mag and a period of about 6.96h. In August 2007, 13 spectra of SDSSJ212531.92-010745.9 covering the full orbital phase range were taken at the TWIN 3.5m telescope at the Calar Alto Observatory (Alm\'{e}ria, Spain). These confirm the typical PG1159 features seen in the SDSS discovery spectrum, together with the Balmer series of hydrogen in emission (plus other emission lines), interpreted as signature of the companion's irradiated side. A radial velocity curve was obtained for both components. Using co-added radial-velocity-corrected spectra, the spectral analysis of the PG1159 star is being refined. The system's lightcurve, obtained during three seasons of photometry with the G\"ottingen 50cm and T\"ubingen 80cm telescopes, was fitted with both the NIGHTFALL and PHOEBE binary simulation programs. An accurate mass determination of the PG1159 component from the radial velocity measurements requires to first derive the inclination, which requires light curve modelling and yields further constraints on radii, effective temperature and separation of the system's components. From the analysis of all data available so far, we present the possible mass range for the PG1159 component of SDSSJ212531.92-010745.9.Comment: 8 pages, in "White dwarfs", proceedings of the 16th European White Dwarf Workshop, eds. E. Garcia-Berro, M. Hernanz, J. Isern, S. Torres, to be published in J. Phys.: Conf. Se

    Direct Observation of Controlled Coupling in an Individual Quantum Dot Molecule

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    We report the direct observation of quantum coupling in individual quantum dot molecules and its manipulation using static electric fields. A pronounced anti-crossing of different excitonic transitions is observed as the electric field is tuned. Comparison of our experimental results with theory shows that the observed anti-crossing occurs between excitons with predominant spatially \emph{direct} and \emph{indirect} character. The electron component of the exciton wavefunction is shown to have molecular character at the anti-crossing and the quantum coupling strength is deduced optically. In addition, we determine the dependence of the coupling strength on the inter-dot separation and identify a field driven transition of the nature of the molecular ground state.Comment: 11 pages, 4 figures submitted to Physical Review Letter

    Protease inhibitors prevent plasminogen-mediated, but not pemphigus vulgaris-induced, acantholysis in human epidermis

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    Pemphigus is an autoimmune blistering disease of the skin and mucous membranes. It is caused by autoantibodies directed against desmosomes, which are the principal adhesion structures between epidermal keratinocytes. Binding of autoantibodies leads to the destruction of desmosomes resulting in the loss of cell-cell adhesion (acantholysis) and epidermal blisters. The plasminogen activator system has been implicated as a proteolytic effector in pemphigus. We have tested inhibitors of the plasminogen activator system with regard to their potential to prevent pemphigus-induced cutaneous pathology. In a human split skin culture system, IgG preparations of sera from pemphigus vulgaris patients caused histopathologic changes (acantholysis) similar to those observed in the original pemphigus disease. All inhibitors that were tested (active site inhibitors directed against uPA, tPA, and/or plasmin; antibodies neutralizing the enzymatic activity of uPA or tPA; substances interfering with the binding of uPA to its specific cell surface receptor uPAR) failed to prevent pemphigus vulgaris IgG-mediated acantholysis. Plasminogen-mediated acantholysis, however, was effectively antagonized by the synthetic active site serine protease inhibitor WX-UK1 or by p-aminomethylbenzoic acid. Our data argue against applying anti-plasminogen activator/anti-plasmin strategies in the management of pemphigus
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