European Preferences for Beef Steak Attributes

A choice experiment is used to evaluate how consumers in London, Frankfurt, and Paris value beef steaks with attributes such as: "hormone-free," "GM-free," farm-specific source verification, and domestic origin. The effect of various consumer characteristics on steak selection is also evaluated. Results suggest that European consumers are significantly heterogeneous in their preferences for beef steak attributes. French and German consumers have a higher willingness to pay to avoid genetically modified feed use than British consumers, while German and British consumers would pay more for growth hormone-free beef. French and German consumers are willing to pay for farm-specific source verification.beef, choice experiment, country of origin, genetically modified, hormones, preference heterogeneity, random parameters, source verification, Consumer/Household Economics,

Nodulation, Nitrogen Fixation, and Organ Dry Weight of Soybean Infested with Southern Corn Rootworm (Coleoptera: Chrysomelidae) Larvae

Nitrogen fixation, nodulation, and organ dry weights of soybean infested with the larvae of the southern corn rootworm, Diabrotica undecimpunctata howardi Barber, were estimated under controlled conditions. Larval southern com rootworm reduced the nitrogen-fixing activity of mid-vegetative and early reproductive soybean, Glycine max Merrill. Soybean of both stages responded to the infestation and subsequent injury by increasing nodulation and organ dry weights of below-ground tissues relative to above-ground tissues. Infestation increased the dry weight of small nodules on vegetative plants and caused a 78.6% increase in the total number of nodules on R5 plants. Leaf area as well as leaf and stem dry weight was reduced in vegetative plants by infestatio

Twirling of Actin by Myosins II and V Observed via Polarized TIRF in a Modified Gliding Assay

The force generated between actin and myosin acts predominantly along the direction of the actin filament, resulting in relative sliding of the thick and thin filaments in muscle or transport of myosin cargos along actin tracks. Previous studies have also detected lateral forces or torques that are generated between actin and myosin, but the origin and biological role of these sideways forces is not known. Here we adapt an actin gliding filament assay in order to measure the rotation of an actin filament about its axis (“twirling”) as it is translocated by myosin. We quantify the rotation by determining the orientation of sparsely incorporated rhodamine-labeledactin monomers, using polarized total internal reflection (polTIRF) microscopy. In order to determine the handedness of the filament rotation, linear incident polarizations in between the standard s- and p-polarizations were generated, decreasing the ambiguity of our probe orientation measurement four-fold. We found that whole myosin II and myosin V both twirl actin with a relatively long (~ µm), left-handed pitch that is insensitive to myosin concentration, filament length and filament velocity

Growing potatoes

Caption title.Digitized 2006 AES MoU

Research proposal no. 1612 for a group-sponsored cooperative research project on increased yields in alkaline pulping.

"February 12, 1970.""The research program as herein proposed will go forward in the Chemistry Group Laboratories of the Division of Natural Materials and Systems and will be under the general supervision of Dr. Irwin A. Pearl, Group Coordinator. Technical Supervision of the program will be the responsibility of Dr. John W. Green, Project Leader, ... Assisting Dr. Green will be Dr. Leland R. Schroeder ... and Dr. John F. Perry representing our engineering and computer disciplines.

The Very Low Mass Component of the Gliese 105 System

Multiple-epoch, multicolor images of the astrometric binary Gliese 105A and its very low mass companion Gliese 105C have been obtained using the Hubble Space Telescope's Wide Field Planetary Camera 2 (WFPC2) and Near-Infrared Camera and Multi-Object Spectrometer (NICMOS). The optical and near-infrared colors of Gl 105C strongly suggest a spectral type of M7V for that star. Relative astrometric measurements spanning 3 yr reveal the first evidence of Gl 105C's orbital motion. Previous long-term astrometric studies at Sproul and McCormick Observatories have shown that the period of Gl 105A's perturbation is approximately 60 yr. To satisfy both the observed orbital motion and Gl 105A's astrometric period, Gl 105C's orbit must have an eccentricity of approximately 0.75 and a semimajor axis of approximately 15 AU. Measurements of Gl 105A's radial velocity over 12 yr show a linear trend with a slope of 11.3 m/s/yr, which is consistent with these orbital constraints and a nearly face-on orbit. As no other faint companions to Gl 105A have been detected, we conclude that Gl 105C is probably the source of the 60-yr astrometric perturbation.Comment: 16 pages, 6 figures; to be published in the October 2000 issue of The Astronomical Journa

A meta-analysis of greater sage-grouse Centrocercus urophasianus nesting and brood rearing habitat

The distribution and range of the greater sage-grouse Centrocercus urophasianus have been reduced by 56% since the European settlement of western North America. Although there is an unprecedented effort to conserve the species, there is still considerable debate about the vegetation composition and structure required for nesting and brood-rearing habitat. We conducted a meta-analysis of vegetation characteristics recorded in studies at nest sites (N  =  24) and brood habitats (N  =  8) to determine if there was an overall effect (Hedge's d) of habitat selection and to estimate average canopy cover of sagebrush Artemisia spp., grass and forbs, and also height of grass at nest sites and brood-rearing areas. We estimated effect sizes from the difference between use (nests and brood areas) and random sampling points for each study, and derived an overall effect size across all studies. Sagebrush cover (d₊₊  =  0.39; 95% C.I.: 0.19-0.54) and grass height (d₊₊ =  0.28; 95% C.I.: 0.13-0.42) were greater at nest sites than at random locations. Vegetation at brood areas had less sagebrush cover (d₊₊  =  -0.17; 95% C.I.: -0.44 - +0.18), significantly taller grasses (d₊₊  =  0.31; 95% C.I.: 0.14-0.45), greater forb (d₊₊  =  0.48; 95% C.I.: 0.30-0.67) and grass cover (d₊₊ =  0.17; 95% C.I.: 0.08-0.27) than at random locations. These patterns were especially evident when we examined early (< 6 weeks post hatching) and late brood-rearing habitats separately. The overall estimates of nest and brood area vegetation variables were consistent with those provided in published guidelines for the management of greater sage-grouse.Keywords: sagebrush, breeding habitat, effect size, greater sage-grouse, Artemisia spp., Hedges’ d, meta-analysi

Identifying epileptogenic abnormality by decomposing intracranial EEG and MEG power spectra

Identifying abnormal electroencephalographic activity is crucial in diagnosis and treatment of epilepsy. Recent studies showed that decomposing brain activity into periodic (oscillatory) and aperiodic (trend across all frequencies) components may illuminate drivers of changes in spectral activity. Using iEEG data from 234 subjects, we constructed a normative map and compared this with a separate cohort of 63 patients with refractory focal epilepsy being considered for neurosurgery. The normative map was computed using three approaches: (i) relative complete band power, (ii) relative band power with the aperiodic component removed (iii) the aperiodic exponent. Corresponding abnormalities were also calculated for each approach in the separate patient cohort. We investigated the spatial profiles of the three approaches, assessed their localizing ability, and replicated our findings in a separate modality using MEG. The normative maps of relative complete band power and relative periodic band power had similar spatial profiles. In the aperiodic normative map, exponent values were highest in the temporal lobe. Abnormality estimated through the complete band power robustly distinguished between good and bad outcome patients. Neither periodic band power nor aperiodic exponent abnormalities distinguished seizure outcome groups. Combining periodic and aperiodic abnormalities improved performance, similar to the complete band power approach. Our findings suggest that sparing cerebral tissue that generates abnormalities in either periodic or aperiodic activity may lead to a poor surgical outcome. Both periodic and aperiodic abnormalities are necessary to distinguish patient outcomes, with neither sufficient in isolation. Future studies could investigate whether periodic or aperiodic abnormalities are affected by the cerebral location or pathology

Rotigotine in Hemodialysis-Associated Restless Legs Syndrome : A Randomized Controlled Trial

Background: Restless legs syndrome (RLS) has been associated with insomnia, decreased quality of life, and increased morbidity and mortality in end-stage renal disease. This randomized controlled trial investigated effects of rotigotine in patients with RLS and end-stage renal disease. Study Design: Double-blind placebo-controlled study. Setting & Participants: Adults with moderate to severe RLS (International RLS Study Group Rating Scale [IRLS] >= 15) and Periodic Limb Movement Index (PLMI) >= 15 who were receiving thrice-weekly hemodialysis enrolled from sites in the United States and Europe. Intervention: Following randomization and titration ( Outcomes & Measurements: Primary efficacy outcome: reduction in PLMI, assessed by ratio of PLMI at end of maintenance to baseline. Secondary/other outcomes (P values exploratory) included mean changes from baseline in PLMI, IRLS, and Clinical Global Impression item 1 (CGI-1 [severity of illness]) score. Results: 30 patients were randomly assigned (rotigotine, 20; placebo, 10); 25 (15; 10) completed the study with evaluable data. Mean (SD) PLMI ratio (end of maintenance to baseline) was 0.7 +/- 0.4 for rotigotine and 1.3 +/- 0.7 for placebo (analysis of covariance treatment ratio, 0.44; 95% CI, 0.22 to 0.88; P = 0.02). Numerical improvements were observed with rotigotine versus placebo in IRLS and CGI-1 (least squares mean treatment differences of -6.08 [95% CI, -12.18 to 0.02; P = 0.05] and -0.81 [95% CI, -1.94 to 0.33; P = 0.2]). 10 of 15 rotigotine and 2 of 10 placebo patients were CGI-1 responders (>= 50% improvement). Hemodialysis did not affect unconjugated rotigotine concentrations. The most common adverse events (>= 2 patients) were nausea (rotigotine, 4 [20%]; placebo, 0); vomiting (3 [15%]; 0); diarrhea (1 [5%]; 2 [20%]); headache (2 [10%]; 0); dyspnea (2 [10%]; 0); and hypertension (2 [10%]; 0). Limitations: Small sample size and short duration. Conclusions: Rotigotine improved periodic limb movements and RLS symptoms in the short term among ESRD patients requiring hemodialysis in a small-scale study. No dose adjustments are necessary for hemodialysis patients. (C) 2016 by the National Kidney Foundation, Inc.Peer reviewe