Novel developments in SBGN-ED and applications

Systems Biology Graphical Notation (SBGN, http://sbgn.org) [1] is an emerging standard for graphical representations of biochemical and cellular processes studied in systems biology. Three different views (Process Description, Entity Relationship, and Activity Flow) cover several aspects of the represented processes in different levels of detail. SBGN helps to communicate biological knowledge more efficient and accurate between different research communities in the life sciences. However, to support SBGN, methods and tools for editing, validating, and translating of SBGN maps are necessary.
We present methods for these tasks and novel developments in SBGN-ED (www.sbgn-ed.org) [2], a tool which allows to create all three types of SBGN maps from scratch, to validate these maps for syntactical and semantical correctness, to translate maps from the KEGG database into SBGN, and to export SBGN maps into several file and image formats. SBGN-ED is based on VANTED (Visualization and Analysis of NeTworks containing Experimental Data, http://www.vanted.org) [3].
As applications of SBGN and SBGN-ED we present furthermore MetaCrop (http://metacrop.ipk-gatersleben.de) [4], a database that summarizes diverse information about metabolic pathways in crop plants, and RIMAS (Regulatory Interaction Maps of Arabidopsis Seed Development, http://rimas.ipk-gatersleben.de) [5], an information portal that provides a comprehensive overview of regulatory pathways and genetic interactions during Arabidopsis embryo and seed development. 

[1] Le Novère, N. et al. (2009) The Systems Biology Graphical Notation. Nature Biotechnology, 27, 735-741.
[2] Czauderna, T., Klukas, C., Schreiber, F. (2010) Editing, validating, and translating of SBGN maps. Bioinformatics, 26 (18), 2340-2341.
[3] Junker, B.H., Klukas, C., Schreiber, F. (2006) VANTED: A system for advanced data analysis and visualization in the context of biological networks. BMC Bioinformatics, 7, 109+.
[4] Grafahrend-Belau, E., Weise, S., Koschützki, D., Scholz, U., Junker, B.H., Schreiber, F. (2008) MetaCrop - A detailed database of crop plant metabolism. Nucleic Acids Research, 36, D954-D958.
[5] Junker, A., Hartmann, A., Schreiber, F., Bäumlein, H. (2010) An engineer's view on regulation of seed development. Trends in Plant Science, 15(6), 303-307.
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Byng’s and Currie’s Commanders: A Still Untold Story of the Canadian Corps

In 1915, the Canadian Corps was little more than a rabble of enthusiastic amateurs. Yet by 1917-18, it had become an accomplished professional fighting force, one characterized by Denis Winter as “much the most effective unit in the BEF” and by Shane Schreiber as “the shock army of the British Empire.” While Canadian military historians have studied this evolution extensively few have examined the decisive element in the transformation—the development of a cadre of proficient senior combat officers. No one questions Currie’s status as Canada’s best fighting general, but of the supporting team he and his predecessor, General Byng, assembled we know precious little. Who, then, were the men commanding the Corps’ four divisions, 12 infantry brigades and supporting machine gun and artillery units—the senior officers whose abilities as trainers and fighters were integral to the CEF’s battlefield success

Revisiting h measured on UK LIS and IR academics

A brief communication appearing in this journal ranked UK LIS and (some) IR academics by their h-index using data derived from Web of Science. In this brief communication, the same academics were re-ranked, using other popular citation databases. It was found that for academics who publish more in computer science forums, their h was significantly different due to highly cited papers missed by Web of Science; consequently their rank changed substantially. The study was widened to a broader set of UK LIS and IR academics where results showed similar statistically significant differences. A variant of h, hmx, was introduced that allowed a ranking of the academics using all citation databases together

Ambisjoner og utfordringer: Bibliotekaren i et profesjonsteoretisk perspektiv

ANMELDELSE:Schreiber,T & Elbeshausen, H (2006). Bibliotekarerne: En profession i et felt af viden, kommunikationog teknologi, T. Schreiber & H. Elbeshausen (red.).Fredriksberg: Forlaget Samfundslitteratur. 221 s.

Fred (Fritz) Schreiber

https://digitalcommons.csp.edu/tc-ohp_interviews_stp/1080/thumbnail.jp