Topological Excitations in the Thirring model

The quantization of the massless Thirring model in the light-cone using functional methods is considered. The need to compactify the coordinate $x^-$ in the light-cone spacetime implies that the quantum effective action for left-handed fermions contains excitations similar to abelian instantons produced by composite of left-handed fermions. Right-handed fermions don't have a similar effective action. Thus, quantum mechanically, chiral symmetry must be broken as a result of the topological excitations. The conserved charge associated to the topological states is quantized. Different cases with only fermionic excitations or bosonic excitations or both can occur depending on the boundary conditions and the value of the coupling.Comment: title changed, one reference added, accepted in Phys. Lett.

Schwarzschild and Synge once again

We complete the historical overview about the geometry of a Schwarzschild black hole at its horizon by emphasizing the contribution made by J. L. Synge in 1950 to its clarification.Comment: 2 pages, LaTeX, submitted for publication; 2 references, one Note, and an Acknowledgement are adde

Fluorescently labeled bacteria provide insight on post-mortem microbial transmigration

AbstractMicrobially mediated mechanisms of human decomposition begin immediately after death, and are a driving force for the conversion of a once living organism to a resource of energy and nutrients. Little is known about post-mortem microbiology in cadavers, particularly the community structure of microflora residing within the cadaver and the dynamics of these communities during decomposition. Recent work suggests these bacterial communities undergo taxa turnover and shifts in community composition throughout the post-mortem interval. In this paper we describe how the microbiome of a living host changes and transmigrates within the body after death thus linking the microbiome of a living individual to post-mortem microbiome changes. These differences in the human post-mortem from the ante-mortem microbiome have demonstrated promise as evidence in death investigations. We investigated the post-mortem structure and function dynamics of Staphylococcus aureus and Clostridium perfringens after intranasal inoculation in the animal model Mus musculus L. (mouse) to identify how transmigration of bacterial species can potentially aid in post-mortem interval estimations. S. aureus was tracked using in vivo and in vitro imaging to determine colonization routes associated with different physiological events of host decomposition, while C. perfringens was tracked using culture-based techniques. Samples were collected at discrete time intervals associated with various physiological events and host decomposition beginning at 1h and ending at 60 days post-mortem. Results suggest that S. aureus reaches its highest concentration at 5–7 days post-mortem then begins to rapidly decrease and is undetectable by culture on day 30. The ability to track these organisms as they move in to once considered sterile space may be useful for sampling during autopsy to aid in determining post-mortem interval range estimations, cause of death, and origins associated with the geographic location of human remains during death investigations

A piezoelectric microvalve for compact high frequency high differential pressure micropumping systems

A piezoelectrically driven hydraulic amplification microvalve for use in compact high-performance hydraulic pumping systems was designed, fabricated, and experimentally characterized. High-frequency, high-force actuation capabilities were enabled through the incorporation of bulk piezoelectric material elements beneath a micromachined annular tethered-piston structure. Large valve stroke at the microscale was achieved with an hydraulic amplification mechanism that amplified (40/spl times/-50/spl times/) the limited stroke of the piezoelectric material into a significantly larger motion of a micromachined valve membrane with attached valve cap. These design features enabled the valve to meet simultaneously a set of high frequency (/spl ges/1 kHz), high pressure(/spl ges/300 kPa), and large stroke (20-30 /spl mu/m) requirements not previously satisfied by other hydraulic flow regulation microvalves. This paper details the design, modeling, fabrication, assembly, and experimental characterization of this valve device. Fabrication challenges are detailed

Quicksort, Largest Bucket, and Min-Wise Hashing with Limited Independence

Randomized algorithms and data structures are often analyzed under the assumption of access to a perfect source of randomness. The most fundamental metric used to measure how "random" a hash function or a random number generator is, is its independence: a sequence of random variables is said to be $k$-independent if every variable is uniform and every size $k$ subset is independent. In this paper we consider three classic algorithms under limited independence. We provide new bounds for randomized quicksort, min-wise hashing and largest bucket size under limited independence. Our results can be summarized as follows. -Randomized quicksort. When pivot elements are computed using a $5$-independent hash function, Karloff and Raghavan, J.ACM'93 showed $O ( n \log n)$ expected worst-case running time for a special version of quicksort. We improve upon this, showing that the same running time is achieved with only $4$-independence. -Min-wise hashing. For a set $A$, consider the probability of a particular element being mapped to the smallest hash value. It is known that $5$-independence implies the optimal probability $O (1 /n)$. Broder et al., STOC'98 showed that $2$-independence implies it is $O(1 / \sqrt{|A|})$. We show a matching lower bound as well as new tight bounds for $3$- and $4$-independent hash functions. -Largest bucket. We consider the case where $n$ balls are distributed to $n$ buckets using a $k$-independent hash function and analyze the largest bucket size. Alon et. al, STOC'97 showed that there exists a $2$-independent hash function implying a bucket of size $\Omega ( n^{1/2})$. We generalize the bound, providing a $k$-independent family of functions that imply size $\Omega ( n^{1/k})$.Comment: Submitted to ICALP 201

Anharmonicities of giant dipole excitations

The role of anharmonic effects on the excitation of the double giant dipole resonance is investigated in a simple macroscopic model.Perturbation theory is used to find energies and wave functions of the anharmonic ascillator.The cross sections for the electromagnetic excitation of the one- and two-phonon giant dipole resonances in energetic heavy-ion collisions are then evaluated through a semiclassical coupled-channel calculation.It is argued that the variations of the strength of the anharmonic potential should be combined with appropriate changes in the oscillator frequency,in order to keep the giant dipole resonance energy consistent with the experimental value.When this is taken into account,the effects of anharmonicities on the double giant dipole resonance excitation probabilities are small and cannot account for the well-known discrepancy between theory and experiment

On the fraction of dark matter in charged massive particles (CHAMPs)

From various cosmological, astrophysical and terrestrial requirements, we derive conservative upper bounds on the present-day fraction of the mass of the Galactic dark matter (DM) halo in charged massive particles (CHAMPs). If dark matter particles are neutral but decay lately into CHAMPs, the lack of detection of heavy hydrogen in sea water and the vertical pressure equilibrium in the Galactic disc turn out to put the most stringent bounds. Adopting very conservative assumptions about the recoiling velocity of CHAMPs in the decay and on the decay energy deposited in baryonic gas, we find that the lifetime for decaying neutral DM must be > (0.9-3.4)x 10^3 Gyr. Even assuming the gyroradii of CHAMPs in the Galactic magnetic field are too small for halo CHAMPs to reach Earth, the present-day fraction of the mass of the Galactic halo in CHAMPs should be < (0.4-1.4)x 10^{-2}. We show that redistributing the DM through the coupling between CHAMPs and the ubiquitous magnetic fields cannot be a solution to the cuspy halo problem in dwarf galaxies.Comment: 21 pages, 2 figures. To appear in JCA

Haloperidol and Ziprasidone for Treatment of Delirium in Critical Illness

BACKGROUND: There are conflicting data on the effects of antipsychotic medications on delirium in patients in the intensive care unit (ICU). METHODS: In a randomized, double-blind, placebo-controlled trial, we assigned patients with acute respiratory failure or shock and hypoactive or hyperactive delirium to receive intravenous boluses of haloperidol (maximum dose, 20 mg daily), ziprasidone (maximum dose, 40 mg daily), or placebo. The volume and dose of a trial drug or placebo was halved or doubled at 12-hour intervals on the basis of the presence or absence of delirium, as detected with the use of the Confusion Assessment Method for the ICU, and of side effects of the intervention. The primary end point was the number of days alive without delirium or coma during the 14-day intervention period. Secondary end points included 30-day and 90-day survival, time to freedom from mechanical ventilation, and time to ICU and hospital discharge. Safety end points included extrapyramidal symptoms and excessive sedation. RESULTS: Written informed consent was obtained from 1183 patients or their authorized representatives. Delirium developed in 566 patients (48%), of whom 89% had hypoactive delirium and 11% had hyperactive delirium. Of the 566 patients, 184 were randomly assigned to receive placebo, 192 to receive haloperidol, and 190 to receive ziprasidone. The median duration of exposure to a trial drug or placebo was 4 days (interquartile range, 3 to 7). The median number of days alive without delirium or coma was 8.5 (95% confidence interval [CI], 5.6 to 9.9) in the placebo group, 7.9 (95% CI, 4.4 to 9.6) in the haloperidol group, and 8.7 (95% CI, 5.9 to 10.0) in the ziprasidone group (P=0.26 for overall effect across trial groups). The use of haloperidol or ziprasidone, as compared with placebo, had no significant effect on the primary end point (odds ratios, 0.88 [95% CI, 0.64 to 1.21] and 1.04 [95% CI, 0.73 to 1.48], respectively). There were no significant between-group differences with respect to the secondary end points or the frequency of extrapyramidal symptoms. CONCLUSIONS: The use of haloperidol or ziprasidone, as compared with placebo, in patients with acute respiratory failure or shock and hypoactive or hyperactive delirium in the ICU did not significantly alter the duration of delirium. (Funded by the National Institutes of Health and the VA Geriatric Research Education and Clinical Center; MIND-USA ClinicalTrials.gov number, NCT01211522 .)

Neutron stars in generalized f(R) gravity

Quartic gravity theory is considered with the Einstein-Hilbert Lagrangean $R+aR^{2}+bR_{\mu \nu}R^{\mu \nu},$ $R_{\mu \nu}$ being Ricci\'s tensor and R the curvature scalar. The parameters $a$ and $b$ are taken of order 1 km$^{2}.$ Arguments are given which suggest that the effective theory so obtained may be a plausible approximation of a viable theory. A numerical integration is performed of the field equations for a free neutron gas. As in the standard Oppenheimer-Volkoff calculation the star mass increases with increasing central density until about 1 solar mass and then decreases. However a dramatic difference exists in the behaviour of the baryon number, which increases monotonically. The calculation suggests that the theory allows stars in equilibrium with arbitrary baryon number, no matter how large.Comment: Keywords: stars, neutron stars; gravity; modified gravity Accepted in Astrophysics and Space Scienc

Field theory models for variable cosmological constant

Anthropic solutions to the cosmological constant problem require seemingly unnatural scalar field potentials with a very small slope or domain walls (branes) with a very small coupling to a four-form field. Here we introduce a class of models in which the smallness of the corresponding parameters can be attributed to a spontaneously broken discrete symmetry. We also demonstrate the equivalence of scalar field and four-form models. Finally, we show how our models can be naturally embedded into a left-right extension of the standard model.Comment: A reference adde