361 research outputs found
Molecular characterization of bacteria associated with the trophosome and the tube of Lamellibrachia sp., a siboglinid annelid from cold seeps in the eastern Mediterranean
Specimens of Lamellibrachia (Annelida: Siboglinidae) were recently discovered at cold seeps in the eastern Mediterranean. In this study, we have investigated the phylogeny and function of intracellular bacterial symbionts inhabiting the trophosome of specimens of Lamellibrachia sp. from the Amon mud volcano, as well as the bacterial assemblages associated with their tube. The dominant intracellular symbiont of Lamellibrachia sp. is a gammaproteobacterium closely related to other sulfide-oxidizing tubeworm symbionts. In vivo uptake experiments show that the tubeworm relies on sulfide for its metabolism, and does not utilize methane. Bacterial communities associated with the tube form biofilms and occur from the anterior to the posterior end of the tube. The diversity of 16S rRNA gene phylotypes includes representatives from the same divisions previously identified from the tube of the vent species Riftia pachyptila, and others commonly found at seeps and vents
OmegaWINGS: OmegaCAM@VST observations of WINGS galaxy clusters
The Wide-field Nearby Galaxy-cluster Survey (WINGS) is a wide-field
multi-wavelength survey of X-ray selected clusters at z =0.04-0.07. The
original 34'x34' WINGS field-of- view has now been extended to cover a 1 sq.deg
field with both photometry and spectroscopy. In this paper we present the
Johnson B and V-band OmegaCAM/VST observations of 46 WINGS clusters, together
with the data reduction, data quality and Sextractor photometric catalogs.
With a median seeing of 1arcs in both bands, our 25-minutes exposures in each
band typically reach the 50% completeness level at V=23.1 mag. The quality of
the astrometric and photometric accuracy has been verified by comparison with
the 2MASS as well as with SDSS astrometry, and SDSS and previous WINGS imaging.
Star/galaxy separation and sky-subtraction procedure have been tested comparing
with previous WINGS data.
The Sextractor photometric catalogues are publicly available at the CDS, and
will be included in the next release of the WINGS database on the VO together
with the OmegaCAM reduced images. These data form the basis for a large ongoing
spectroscopic campaign with AAOmega/AAT and is being employed for a variety of
studies. [abridged]Comment: submitted to A&
The VOICE Survey : VST Optical Imaging of the CDFS and ES1 Fields
IndexaciĂłn: Scopus.We present the VST Optical Imaging of the CDFS and ES1 Fields (VOICE) Survey, a VST INAF Guaranteed Time program designed to provide optical coverage of two 4 deg2 cosmic windows in the Southern hemisphere. VOICE provides the first, multi-band deep optical imaging of these sky regions, thus complementing and enhancing the rich legacy of longer-wavelength surveys with VISTA, Spitzer, Herschel and ATCA available in these areas and paving the way for upcoming observations with facilities such as the LSST, MeerKAT and the SKA. VOICE exploits VST's OmegaCAM optical imaging capabilities and completes the reduction of WFI data available within the ES1 fields as part of the ESO-Spitzer Imaging Extragalactic Survey (ESIS) program providing ugri and uBVR coverage of 4 and 4 deg2 areas within the CDFS and ES1 field respectively. We present the survey's science rationale and observing strategy, the data reduction and multi-wavelength data fusion pipeline. Survey data products and their future updates will be released at http://www.mattiavaccari.net/voice/ and on CDS/VizieR.https://pos.sissa.it/275/026/pd
Estimation of the effect of SLCO1B1 polymorphisms on lopinavir plasma concentration in HIV-Infected Adults
Background—The organic anion transporting polypeptides (OATP)/SLCO family represents an important class of hepatic drug uptake transporters that mediate the sodium independent transport of a diverse range of amphipathic organic compounds, including the protease inhibitors. The
SLCO1B1 521T>C (rs4149056) single nucleotide polymorphism (SNP) has been consistently associated with reduced transport activity in vivo, and we previously showed an association of this polymorphism with lopinavir plasma concentrations. The aim of this study was to develop a
population pharmacokinetic (PK) model to quantify the impact of 521T>C.
Methods—A population PK analysis was performed with 594 plasma samples from 375 patients receiving lopinavir/ritonavir. Non-linear mixed effects modelling was applied to explore the effects of SLCO1B1 521T>C and patient demographics. Simulations of the lopinavir
concentration profile were performed with different dosing regimens considering the different alleles.
Results—A one-compartment model with first-order absorption best described the data.
Population clearance was 5.67 L/h with inter-patient variability of 37%. Body weight was the only
demographic factor influencing clearance, which increased 0.5 L/h for every 10 kg increase.
Homozygosity for the C allele was associated with a 37% lower clearance, and 14% for heterozygosity, which were statistically significant.
Conclusion—These data show an association between SLCO1B1 521T>C and lopinavir clearance. The association is likely to be mediated through reduced uptake by hepatocytes leading
to higher plasma concentrations of lopinavir. Further studies are now required to confirm the association and to assess the influence of other polymorphisms in the SLCO family on lopinavir
PK
SUDARE-VOICE variability-selection of Active Galaxies in the Chandra Deep Field South and the SERVS/SWIRE region
One of the most peculiar characteristics of Active Galactic Nuclei (AGN) is
their variability over all wavelengths. This property has been used in the past
to select AGN samples and is foreseen to be one of the detection techniques
applied in future multi-epoch surveys, complementing photometric and
spectroscopic methods.
In this paper, we aim to construct and characterise an AGN sample using a
multi-epoch dataset in the r band from the SUDARE-VOICE survey.
Our work makes use of the VST monitoring program of an area surrounding the
Chandra Deep Field South to select variable sources. We use data spanning a six
month period over an area of 2 square degrees, to identify AGN based on their
photometric variability.
The selected sample includes 175 AGN candidates with magnitude r < 23 mag. We
distinguish different classes of variable sources through their lightcurves, as
well as X-ray, spectroscopic, SED, optical and IR information overlapping with
our survey.
We find that 12% of the sample (21/175) is represented by SN. Of the
remaining sources, 4% (6/154) are stars, while 66% (102/154) are likely AGNs
based on the available diagnostics. We estimate an upper limit to the
contamination of the variability selected AGN sample of about 34%, but we point
out that restricting the analysis to the sources with available
multi-wavelength ancillary information, the purity of our sample is close to
80% (102 AGN out of 128 non-SN sources with multi-wavelength diagnostics). Our
work thus confirms the efficiency of the variability selection method in
agreement with our previous work on the COSMOS field; in addition we show that
the variability approach is roughly consistent with the infrared selection.Comment: Published in A & A, 15 pages, 6 figure
Optically variable active galactic nuclei in the 3 yr VST survey of the COSMOS field
The analysis of the variability of active galactic nuclei (AGNs) at different
wavelengths and the study of possible correlations among different spectral
windows are nowadays a major field of inquiry. Optical variability has been
largely used to identify AGNs in multivisit surveys. The strength of a
selection based on optical variability lies in the chance to analyze data from
surveys of large sky areas by ground-based telescopes. However the
effectiveness of optical variability selection, with respect to other
multiwavelength techniques, has been poorly studied down to the depth expected
from next generation surveys. Here we present the results of our r-band
analysis of a sample of 299 optically variable AGN candidates in the VST survey
of the COSMOS field, counting 54 visits spread over three observing seasons
spanning > 3 yr. This dataset is > 3 times larger in size than the one
presented in our previous analysis (De Cicco et al. 2015), and the observing
baseline is ~8 times longer. We push towards deeper magnitudes (r(AB) ~23.5
mag) compared to past studies; we make wide use of ancillary multiwavelength
catalogs in order to confirm the nature of our AGN candidates, and constrain
the accuracy of the method based on spectroscopic and photometric diagnostics.
We also perform tests aimed at assessing the relevance of dense sampling in
view of future wide-field surveys. We demonstrate that the method allows the
selection of high-purity (> 86%) samples. We take advantage of the longer
observing baseline to achieve great improvement in the completeness of our
sample with respect to X-ray and spectroscopically confirmed samples of AGNs
(59%, vs. ~15% in our previous work), as well as in the completeness of
unobscured and obscured AGNs. The effectiveness of the method confirms the
importance to develop future, more refined techniques for the automated
analysis of larger datasets.Comment: 21 pages, 10 figures; accepted for publication in A&
Supernova rates from the SUDARE VST-Omegacam search II. Rates in a galaxy sample
This is the second paper of a series in which we present measurements of the
Supernova (SN) rates from the SUDARE survey. In this paper, we study the trend
of the SN rates with the intrinsic colours, the star formation activity and the
mass of the parent galaxies. We have considered a sample of about 130000
galaxies and a SN sample of about 50 events. We found that the SN Ia rate per
unit mass is higher by a factor of six in the star-forming galaxies with
respect to the passive galaxies. The SN Ia rate per unit mass is also higher in
the less massive galaxies that are also younger. These results suggest a
distribution of the delay times (DTD) less populated at long delay times than
at short delays. The CC SN rate per unit mass is proportional to both the sSFR
and the galaxy mass. The trends of the Type Ia and CC SN rates as a function of
the sSFR and the galaxy mass that we observed from SUDARE data are in agreement
with literature results at different redshifts. The expected number of SNe Ia
is in agreement with the observed one for all four DTD models considered both
in passive and star-forming galaxies so we can not discriminate between
different progenitor scenarios. The expected number of CC SNe is higher than
the observed one, suggesting a higher limit for the minimum progenitor mass. We
also compare the expected and observed trends of the SN Ia rate with the
intrinsic U - J colour of the parent galaxy, assumed as a tracer of the age
distribution. While the slope of the relation between the SN Ia rate and the U
- J color in star-forming galaxies can be reproduced well by all four DTD
models considered, only the steepest of them is able to account for the rates
and colour in star-forming and passive galaxies with the same value of the SN
Ia production efficiency.Comment: A& A accepte
SOXS: a wide band spectrograph to follow up transients
SOXS (Son Of X-Shooter) will be a spectrograph for the ESO NTT telescope
capable to cover the optical and NIR bands, based on the heritage of the
X-Shooter at the ESO-VLT. SOXS will be built and run by an international
consortium, carrying out rapid and longer term Target of Opportunity requests
on a variety of astronomical objects. SOXS will observe all kind of transient
and variable sources from different surveys. These will be a mixture of fast
alerts (e.g. gamma-ray bursts, gravitational waves, neutrino events), mid-term
alerts (e.g. supernovae, X-ray transients), fixed time events (e.g. close-by
passage of minor bodies). While the focus is on transients and variables, still
there is a wide range of other astrophysical targets and science topics that
will benefit from SOXS. The design foresees a spectrograph with a
Resolution-Slit product ~ 4500, capable of simultaneously observing over the
entire band the complete spectral range from the U- to the H-band. The limiting
magnitude of R~20 (1 hr at S/N~10) is suited to study transients identified
from on-going imaging surveys. Light imaging capabilities in the optical band
(grizy) are also envisaged to allow for multi-band photometry of the faintest
transients. This paper outlines the status of the project, now in Final Design
Phase.Comment: 12 pages, 14 figures, to be published in SPIE Proceedings 1070
Overview of the VIRMOS instrument and data reduction software packages
VIMOS is a spectrograph with imaging capabilities which will be mounted on the Nasmyth B focus of VLT UT. The main characteristics of VIMOS are the multiplexing spectral capabilities up to spectra per exposure and the presence of an Integral Field Unit IFU which
allows spectrophotometry of 1 squared arcmin field. To reach the goal of 800 spectra per field VIMOS has
been designed with a large field of view divided into
quadrants each quadrant being by all means
a full spectrograph on its own Spectra are obtained using masks with slits which are designed by the
astronomer. The ESO VLT Project has devised a general Data Flow within which all VLT instruments have to
operate During design and development of VIMOS instrument software we had to deal with the VLT
general concept and adapt it to our needs
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