Nano-Sized Hydrogel Composites Based on N-Isopropylacrylamide and Magnetite for Controlled Drug Delivery

Synthesis and characterization studies of promising nano-sized hydrogel composites based on nisopropylacrylamide and magnetite have been studied. N-isopropylacrylamide (NIPA) gel component was used as a carrier of various drugs, magnetite was used as a magneto-responsive component. Presence of magnetite it was proved by EPR method. Composite nanoparticles were characterized by electron microscopy (TEM) and by dynamyc light scattering (DLS) method. It was shown that the average size of nanoparticles is 50 or 100 nm, depending on the method of preparation. The hydrogel is characterized by clear phase transition between swollen and collapsed state upon heating above 32⁰C. Rapid release of the incorporated drug (as a model was used the photosensibilizer -Methylene Blue) observed during thermoresponsive nanocomposite gels heating in the physiologically acceptable range, but still above phase transition temperature (up to 40–50 ⁰C), allows application of the discussed drug delivery systems in medical hyperthermia

Nano-Sized Hydrogel Composites Based on N-Isopropylacrylamide and Magnetite for Controlled Drug Delivery

Synthesis and characterization studies of promising nano-sized hydrogel composites based on nisopropylacrylamide and magnetite have been studied. N-isopropylacrylamide (NIPA) gel component was used as a carrier of various drugs, magnetite was used as a magneto-responsive component. Presence of magnetite it was proved by EPR method. Composite nanoparticles were characterized by electron microscopy (TEM) and by dynamyc light scattering (DLS) method. It was shown that the average size of nanoparticles is 50 or 100 nm, depending on the method of preparation. The hydrogel is characterized by clear phase transition between swollen and collapsed state upon heating above 32⁰C. Rapid release of the incorporated drug (as a model was used the photosensibilizer -Methylene Blue) observed during thermoresponsive nanocomposite gels heating in the physiologically acceptable range, but still above phase transition temperature (up to 40–50 ⁰C), allows application of the discussed drug delivery systems in medical hyperthermia

X-ray Diffraction Analysis of the Chromium-containing Electroerosion Powders of Micro - and Nanoparticles

Presents the results of a study of x-ray analysis of the powder obtained by electro erosion dispersing of waste nichrome H15N60 brand in kerosene lighting. The major phases in Nickel-chromium powder obtained by electroerosion dispersion method in kerosene lighting are Ni and Si2O

Boundary effects in large deviation problems

Projet MEVALWe get explicit formulas for large deviation problems in [??] with a discontinuity along an hyperplane and on [??] These quite unexpected results are obtained by using new simple probabilistic techniques

X-ray Diffraction Analysis of the Chromium-containing Electroerosion Powders of Micro - and Nanoparticles

Presents the results of a study of x-ray analysis of the powder obtained by electro erosion dispersing of waste nichrome H15N60 brand in kerosene lighting. The major phases in Nickel-chromium powder obtained by electroerosion dispersion method in kerosene lighting are Ni and Si2O

Boundary effects in large deviation problems

Programme 1 : Architectures paralleles, bases de donnees, reseaux et systemes distribuesSIGLEAvailable at INIST (FR), Document Supply Service, under shelf-number : 14802 E, issue : a.1993 n.1999 / INIST-CNRS - Institut de l'Information Scientifique et TechniqueFRFranc