34 research outputs found

    A petri nets based design of cognitive radios using distributed signal processing

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    AbstractReconfigurability for transceivers for wireless access networks like Bluetooth, WiMAX and W-LAN will become increasingly important. An appropriately flexible and reliable software architecture, allowing the concurrent processing of different controlling tasks for wireless terminals will hence be an important asset. Already during the 1980s reconfigurable receivers were developed for radio intelligence in the short wave range and the concept of software radio (SR) was born. A software defined radio (SDR) is a practical version of an SR: The received signals are sampled after a suitable band selection filter, usually in the base band or a low intermediate frequency band. The signal processing in both SR and SDR requires a considerable amount of concurrent processes. Since Petri nets (PNs) are both simple and strong tools for the description and the design of such concurrent processes, it is recommendable to deploy them for SDR. SDRs have paved the way towards cognitive radios (CRs), which are based on SDRs that additionally sense their environments, track changes, and react upon their findings. A CR is an autonomous unit in a communications environment that frequently exchanges information with the networks it is able to access as well as with other CRs. In this communication, the authors will introduce a realization concept for a CR which forms the basis of a hardware/firmware demonstrator developed by the authors. This demonstrator makes use of a digital signal processor (DSP) which forms the core of the design and flexibly programmable hardware accelerators based on field programmable gate arrays (FPGAs). The authors will describe the solution also in view of the recent developments of IEEE 802.2

    Efficient production of multi-modified pigs for xenotransplantation by ‘combineering’, gene stacking and gene editing

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    Xenotransplantation from pigs could alleviate the shortage of human tissues and organs for transplantation. Means have been identified to overcome hyperacute rejection and acute vascular rejection mechanisms mounted by the recipient. The challenge is to combine multiple genetic modifications to enable normal animal breeding and meet the demand for transplants. We used two methods to colocate xenoprotective transgenes at one locus, sequential targeted transgene placement - ‘gene stacking’, and cointegration of multiple engineered large vectors - ‘combineering’, to generate pigs carrying modifications considered necessary to inhibit short to mid-term xenograft rejection. Pigs were generated by serial nuclear transfer and analysed at intermediate stages. Human complement inhibitors CD46, CD55 and CD59 were abundantly expressed in all tissues examined, human HO1 and human A20 were widely expressed. ZFN or CRISPR/Cas9 mediated homozygous GGTA1 and CMAH knockout abolished α-Gal and Neu5Gc epitopes. Cells from multi-transgenic piglets showed complete protection against human complement-mediated lysis, even before GGTA1 knockout. Blockade of endothelial activation reduced TNFα-induced E-selectin expression, IFNγ-induced MHC class-II upregulation and TNFα/cycloheximide caspase induction. Microbial analysis found no PERV-C, PCMV or 13 other infectious agents. These animals are a major advance towards clinical porcine xenotransplantation and demonstrate that livestock engineering has come of age

    Fülöp Grünvald (1887-1964)

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    Porodica Fülöp-a Grünvald-a poreklom je iz Ceceja. Za vreme oslobodilačkog rata 1848. njegov deda bio je nakupac konja za vojsku. Njegov otac, Mano Grünvald, došao je u Šopron kao mladić i bio rabin Ortodoksne jevrejske opštine sve do smrti 1929. godine. Fülop se školovao u Šopronu. Bio je učitelj u Muškoj građanskoj školi, a od 1919. prešao je u novootvorenu Jevrejsku mušku gimnaziju. Ovoj školi posvetio je sav svoj život. Od 1948. do penzionisanja 1958, bio je direktor Jevrejske gimnazije. Poslednjih godina života vodio je katedru istorije na Zemaljskom rabinskom seminaru u Budimpešti, a posebno je predavao istoriju mađarskih Jevreja. Bio je kustos, a zatim direktor Mađarskog jevrejskog muzeja. Eksponate je najvećim delom sam nalazio i sakupljao, a tokom nemačke okupacije i sačuvao. Ostao je veran svom rodnom gradu Šopronu kome je izuzetno doprineo stvaranjem Zbirke jevrejske umetnosti u zgradi srednjovekovne sinagoge.Fülöp Grünvald's family is originally from Cecej. During the liberation war of 1848, his grandfather was a horse buyer for the army. His father, Mano Grünwald, came to Sopron as a young man and was a rabbi of the Orthodox Jewish Community until his death in 1929. Fülop was educated in Sopron. He was a teacher at the Men's Civic School, and since 1919, he transferred to the newly opened Jewish Men's High School. He has dedicated his life to this school. From 1948 until his retirement in 1958, he was the director of the Jewish High School. In the last years of his life, he held the Chair of History at the Land Rabbinical Seminar in Budapest and especially taught the history of Hungarian Jews. He was a curator and then director of the Hungarian Jewish Museum. For the most part, I found and collected the exhibits, and preserved them during the German occupation. He remained true to his hometown of Sopron, to whom he made a tremendous contribution by creating the Collection of Jewish Art in the Medieval Synagogue Building

    Plasma autoantibodies in patients with Affective and Schizophrenic Spectrum Disorders

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    Background: A number of results emphasize autoimmune characteristics in psychiatric diseases, including Affective (AF) and Schizophrenic (SZ) Spectrum Disorders. Study subjects and methods: In this study, serum/plasma samples of n=34 AF (ICD-10 F30-F33) and n=47 SZ (ICD-10 F20-F25) patients, as well as n=10 healthy controls (HDs), were tested for autoantibodies directed against cytokines and different Type I, Type II and Type III interferons using Luminex® technology. Results: Significant amounts of autoantibodies against cytokines were found. Specifically, IFN- λ (AF n=4, SZ n=4), IFN- ω (AF n=2, SZ n=3), and TNF-α (AF n=4, SZ n=1) were selectively increased. Conclusion: The results support autoimmune dysregulation as a contributing factor in psychiatric diseases. Interestingly, the detected patterns were not different between AF and SZ patients. The humoral immunity against common virus infections such as EBV, CMV, HSV-1 and HHV-6 is currently tested

    Multimodal Asynchronous Kalman Filter for monitoring unstable rock slopes

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    AbstractUnstable rock slopes pose a hazard to inhabitants and infrastructure in their vicinity, necessitating advanced monitoring methodologies for timely risk assessment and mitigation. Recent geotechnical monitoring techniques often rely on sensor data fusion to enhance forecasting for imminent failures. Our investigation extends beyond a single sensor type to data fusion for heterogeneous sensor networks using a Multimodal Asynchronous Kalman Filter. We illustrate the application of the proposed method on a case study data set consisting of data from an on-site sensor network enriched by remote sensing data. Employing a Multimodal Asynchronous Kalman Filter, we capitalise on the distinct resolutions inherent in each sensor input. The outcome was a combined dataset with a high spatiotemporal resolution. Our approach facilitates the estimation of essential physical attributes for monitored objects, encompassing translation, rotation, velocities and accelerations. The case study site was an unstable rock section of ca. 50.000 m3 in Aurland, Norway, which collapsed as a multi-stage failure in July 2023. Our method can be transposed to various sites with distinct sensor networks, enhancing state estimations for objects on unstable rock slopes. These estimations can significantly improve applications such as risk assessment and robust early-warning systems, enhancing predictions of critical failure points

    Disassembly analysis of slates: Design for repair and recycling evaluation. Final report: Version August 2013

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    This project was initiated by Fraunhofer IZM, Berlin, to investigate the current status of slate designs with respect to repair and recycling. Following the Energy Star definition, slate computing devices are defined as a type of computer lacking a physical keyboard, relying solely on touchscreen input, having solely a wireless network connection (e.g., Wi-Fi, 3G), and primarily powered from an internal battery (with connection to the mains for charging, not primary powering of the device). EPEAT supported this project. An overarching objective upon request by EPEAT is to create an independent evidence base for future stakeholder discussions on EPEAT criteria for slates. It is not the objective of this study to propose such criteria, nor did the study take into account all facets to def ine such criteria. Definitely, additional aspects and arguments need to be considered thoroughly in the course of the upcoming stakeholder process
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