762 research outputs found
Metering gun for dispensing precisely measured charges of fluid
A cyclically operable fluid dispenser for use in dispensing precisely measured charges of potable water aboard spacecraft is described. The dispenser is characterized by (1) a sealed housing adapted to be held within a crewman's palm and coupled with a pressurized source of potable water; (2) a dispensing jet projected from the housing and configured to be received within a crewman's lips; (3) an expansible measuring chamber for measuring charges of drinking water received from the source; (4) and a dispenser actuator including a lever extended from the housing to be digitated for initiating operational cycles, whereby precisely measured charges of potable water selectively are delivered for drinking purposes in a weightless environment
Non-Markovian quantum state diffusion for absorption spectra of molecular aggregates
In many molecular systems one encounters the situation where electronic
excitations couple to a quasi-continuum of phonon modes. That continuum may be
highly structured e.g. due to some weakly damped high frequency modes. To
handle such a situation, an approach combining the non-Markovian quantum state
diffusion (NMQSD) description of open quantum systems with an efficient but
abstract approximation was recently applied to calculate energy transfer and
absorption spectra of molecular aggregates [Roden, Eisfeld, Wolff, Strunz, PRL
103 (2009) 058301]. To explore the validity of the used approximation for such
complicated systems, in the present work we compare the calculated
(approximative) absorption spectra with exact results. These are obtained from
the method of pseudomodes, which we show to be capable of determining the exact
spectra for small aggregates and a few pseudomodes. It turns out that in the
cases considered, the results of the two approaches mostly agree quite well.
The advantages and disadvantages of the two approaches are discussed
Quantitative mass spectrometry and PAR-CLIP to identify RNA-protein interactions
Systematic analysis of the RNA-protein interactome requires robust and scalable methods. We here show the combination of two completely orthogonal, generic techniques to identify RNA-protein interactions: PAR-CLIP reveals a collection of RNAs bound to a protein whereas SILAC-based RNA pull-downs identify a group of proteins bound to an RNA. We investigated binding sites for five different proteins (IGF2BP1-3, QKI and PUM2) exhibiting different binding patterns. We report near perfect agreement between the two approaches. Nevertheless, they are non-redundant, and ideally complement each other to map the RNA-protein interaction network
Multiscale modelling and simulation, 13th international workshop
Multiscale Modelling and Simulation (MMS) is a cornerstone in the today's research in computational science. Simulations containing multiple models, with each model operating at a different temporal or spatial scale, are a challenging setting that frequently require innovative approaches in areas such as scale bridging, code deployment, error quantification, and scientific analysis. The aim of the MMS workshop is to encourage and consolidate the progress in this multidisciplinary research field, both in the areas of the scientific applications and the underlying infrastructures that enable these applications. Here we briefly introduce the scope of the workshop and highlight some of the key aspects of this year's submissions
Nonlinear resonance reflection from and transmission through a dense glassy system built up of oriented linear Frenkel chains: two-level models
A theoretical study of the resonance optical response of assemblies of
oriented short (as compared to an optical wavelength) linear Frenkel chains is
carried out using a two-level model. We show that both transmittivity and
reflectivity of the film may behave in a bistable fashion and analyze how the
effects found depend on the film thickness and on the inhomogeneous width of
the exciton optical transition.Comment: 26 pages, 9 figure
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