1,406 research outputs found
Possible multiparticle ridge-like correlations in very high multiplicity proton-proton collisions
The CMS collaboration at the LHC has reported a remarkable and unexpected
phenomenon in very high-multiplicity high energy proton-proton collisions: a
positive correlation between two particles produced at similar azimuthal
angles, spanning a large range in rapidity. We suggest that this "ridge"-like
correlation may be a reflection of the rare events generated by the collision
of aligned flux tubes connecting the valence quarks in the wave functions of
the colliding protons. The "spray" of particles resulting from the approximate
line source produced in such inelastic collisions then gives rise to events
with a strong correlation between particles produced over a large range of both
positive and negative rapidity. We suggest an additional variable that is
sensitive to such a line source which is related to a commonly used measure,
ellipticity.Comment: Updated figure. Version to be published in Physics Letters
THE SYNTHESIS, ASSEMBLY, AND SECRETION OF GAMMA GLOBULIN BY MOUSE MYELOMA CELLS : VI. ASSEMBLY OF IGM PROTEINS
The study of the synthesis, assembly, and secretion of IgM by seven murine myeloma tumors has revealed that free mu chain can be detected intracellularly after release from the ribosome. It combines with light chains to form µL. The major intracellular protein in six of the seven tumors was the 8S subunit. One tumor contained considerable amounts of 19S material intracellularly. Those tumors that did not contain 19S IgM intracellulariy appeared to assemble the subunits outside the cell
Exploring Metacognition as a Support for Learning Transfer
The ability to transfer learning to new situations lies at the heart of lifelong learning and the employability of university graduates. Because students are often unaware of the importance of learning transfer and staff do not always explicitly articulate this expectation, this article explores the idea that metacognition (intentional awareness and the use of that awareness) might enhance the development of learning transfer. Our exploratory study includes results from a survey of 74 staff and 118 students from five institutions in Australia, Belgium, UK, and USA. Our data indicate that many staff and a majority of students do not have a clear understanding of what learning transfer entails, and that there are many mismatches between staff and student perceptions, attitudes, and behaviors regarding learning transfer. This helps explain why learning transfer does not occur as often as it could. We found significant positive correlations between thinking about transfer and thinking about learning processes and the likelihood to use awareness to guide practice. These support the idea that metacognition might enhance learning transfer. We offer suggestions for future scholarship of teaching and learning
Molecular characterization of the humoral responses to Cryptococcus neoformans infection and glucuronoxylomannan-tetanus toxoid conjugate immunization.
Mode regularization of the susy sphaleron and kink: zero modes and discrete gauge symmetry
To obtain the one-loop corrections to the mass of a kink by mode
regularization, one may take one-half the result for the mass of a widely
separated kink-antikink (or sphaleron) system, where the two bosonic zero modes
count as two degrees of freedom, but the two fermionic zero modes as only one
degree of freedom in the sums over modes. For a single kink, there is one
bosonic zero mode degree of freedom, but it is necessary to average over four
sets of fermionic boundary conditions in order (i) to preserve the fermionic
Z gauge invariance , (ii) to satisfy the basic principle of
mode regularization that the boundary conditions in the trivial and the kink
sector should be the same, (iii) in order that the energy stored at the
boundaries cancels and (iv) to avoid obtaining a finite, uniformly distributed
energy which would violate cluster decomposition. The average number of
fermionic zero-energy degrees of freedom in the presence of the kink is then
indeed 1/2. For boundary conditions leading to only one fermionic zero-energy
solution, the Z gauge invariance identifies two seemingly distinct `vacua'
as the same physical ground state, and the single fermionic zero-energy
solution does not correspond to a degree of freedom. Other boundary conditions
lead to two spatially separated solutions, corresponding to
one (spatially delocalized) degree of freedom. This nonlocality is consistent
with the principle of cluster decomposition for correlators of observables.Comment: 32 pages, 5 figure
Predicting the public health benefit of vaccinating cattle against Escherichia coli O157
Identifying the major sources of risk in disease transmission is key to designing effective controls. However, understanding of transmission dynamics across species boundaries is typically poor, making the design and evaluation of controls particularly challenging for zoonotic pathogens. One such global pathogen is Escherichia coli O157, which causes a serious and sometimes fatal gastrointestinal illness. Cattle are the main reservoir for E. coli O157, and vaccines for cattle now exist. However, adoption of vaccines is being delayed by conflicting responsibilities of veterinary and public health agencies, economic drivers, and because clinical trials cannot easily test interventions across species boundaries, lack of information on the public health benefits. Here, we examine transmission risk across the cattle–human species boundary and show three key results. First, supershedding of the pathogen by cattle is associated with the genetic marker stx2. Second, by quantifying the link between shedding density in cattle and human risk, we show that only the relatively rare supershedding events contribute significantly to human risk. Third, we show that this finding has profound consequences for the public health benefits of the cattle vaccine. A naïve evaluation based on efficacy in cattle would suggest a 50% reduction in risk; however, because the vaccine targets the major source of human risk, we predict a reduction in human cases of nearly 85%. By accounting for nonlinearities in transmission across the human–animal interface, we show that adoption of these vaccines by the livestock industry could prevent substantial numbers of human E. coli O157 cases
Reformulating the Schrodinger equation as a Shabat-Zakharov system
We reformulate the second-order Schrodinger equation as a set of two coupled
first order differential equations, a so-called "Shabat-Zakharov system",
(sometimes called a "Zakharov-Shabat" system). There is considerable
flexibility in this approach, and we emphasise the utility of introducing an
"auxiliary condition" or "gauge condition" that is used to cut down the degrees
of freedom. Using this formalism, we derive the explicit (but formal) general
solution to the Schrodinger equation. The general solution depends on three
arbitrarily chosen functions, and a path-ordered exponential matrix. If one
considers path ordering to be an "elementary" process, then this represents
complete quadrature, albeit formal, of the second-order linear ODE.Comment: 18 pages, plain LaTe
A compact statistical model of the song syntax in Bengalese finch
Songs of many songbird species consist of variable sequences of a finite
number of syllables. A common approach for characterizing the syntax of these
complex syllable sequences is to use transition probabilities between the
syllables. This is equivalent to the Markov model, in which each syllable is
associated with one state, and the transition probabilities between the states
do not depend on the state transition history. Here we analyze the song syntax
in a Bengalese finch. We show that the Markov model fails to capture the
statistical properties of the syllable sequences. Instead, a state transition
model that accurately describes the statistics of the syllable sequences
includes adaptation of the self-transition probabilities when states are
repeatedly revisited, and allows associations of more than one state to the
same syllable. Such a model does not increase the model complexity
significantly. Mathematically, the model is a partially observable Markov model
with adaptation (POMMA). The success of the POMMA supports the branching chain
network hypothesis of how syntax is controlled within the premotor song nucleus
HVC, and suggests that adaptation and many-to-one mapping from neural
substrates to syllables are important features of the neural control of complex
song syntax
The CMS Event Builder
The data acquisition system of the CMS experiment at the Large Hadron
Collider will employ an event builder which will combine data from about 500
data sources into full events at an aggregate throughput of 100 GByte/s.
Several architectures and switch technologies have been evaluated for the DAQ
Technical Design Report by measurements with test benches and by simulation.
This paper describes studies of an EVB test-bench based on 64 PCs acting as
data sources and data consumers and employing both Gigabit Ethernet and Myrinet
technologies as the interconnect. In the case of Ethernet, protocols based on
Layer-2 frames and on TCP/IP are evaluated. Results from ongoing studies,
including measurements on throughput and scaling are presented.
The architecture of the baseline CMS event builder will be outlined. The
event builder is organised into two stages with intelligent buffers in between.
The first stage contains 64 switches performing a first level of data
concentration by building super-fragments from fragments of 8 data sources. The
second stage combines the 64 super-fragments into full events. This
architecture allows installation of the second stage of the event builder in
steps, with the overall throughput scaling linearly with the number of switches
in the second stage. Possible implementations of the components of the event
builder are discussed and the expected performance of the full event builder is
outlined.Comment: Conference CHEP0
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