962 research outputs found

    Adaptive neural control for MACE II

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    Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/76789/1/AIAA-1999-4588-533.pd

    Stochastic-based adaptive control vibration control for MACE II

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    Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/76388/1/AIAA-2001-4644-483.pd

    Trions in a periodic potential

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    The group-theoretical classification of trion states is presented. It is based on considerations of products of irreducible representations of the 2D translation group. For a given BvK period N degeneracy of obtained states is N^2. Trions consist of two identical particles so the symmetrization of states with respect to particles transposition is considered. Completely antisymmetric states can be constructed by introducing antisymmetric spin functions. Two symmetry adapted bases are considered. The third possibility is postponed for the further investigations.Comment: revtex, 5 p., sub. to Physica

    Electrostatic control of a membrane using adaptive feedback linearization

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    Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/76357/1/AIAA-1998-4139-522.pd

    Method and Apparatus for Powered Descent Guidance

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    A method and apparatus for landing a spacecraft having thrusters with non-convex constraints is described. The method first computes a solution to a minimum error landing problem for a convexified constraints, then applies that solution to a minimum fuel landing problem for convexified constraints. The result is a solution that is a minimum error and minimum fuel solution that is also a feasible solution to the analogous system with non-convex thruster constraints

    Risk-Benefit Profiles of Women Using Tamoxifen for Chemoprevention

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    Tamoxifen has been US Food and Drug Administration–approved for primary prevention of breast cancer since 1998 but has not been widely adopted, in part because of increased risk of serious side effects. Little is known about the risk-benefit profiles of women who use chemoprevention outside of a clinical trial. We examined characteristics associated with initiation and discontinuation of tamoxifen for primary prevention of breast cancer within a large cohort of women with a first-degree family history of breast cancer

    A Wide-Field Study of the z~0.8 Cluster RX J0152.7-1357: the Role of Environment in the Formation of the Red-Sequence

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    [ABRIDGED] We present the first results from the largest spectroscopic survey to date of an intermediate redshift galaxy cluster, the z=0.834 cluster RX J0152.7-1357. We use the colors of galaxies, assembled from a D~12 Mpc region centered on the cluster, to investigate the properties of the red-sequence as a function of density and clustercentric radius. Our wide-field multi-slit survey with a low-dispersion prism in the IMACS spectrograph at Magellan allowed us to identify 475 new members of the cluster and its surrounding large scale structure with a redshift accuracy of dz/(1+z)~1% and a contamination rate of ~2% for galaxies with i<23.75 mag. We combine these new members with the 279 previously known spectroscopic members to give a total of 754 galaxies from which we obtain a mass-limited sample of 300 galaxies with stellar masses M>4x10^{10} M_sun. We find that the red galaxy fraction is 93+/-3% in the two merging cores of the cluster and declines to a level of 64+/-3% at projected clustercentric radii R>~3 Mpc. At these large projected distances, the correlation between clustercentric radius and local density is nonexistent. This allows an assessment of the influence of the local environment on galaxy evolution, as opposed to mechanisms that operate on cluster scales. Even beyond R>3 Mpc we find an increasing fraction of red galaxies with increasing local density. The red fraction at the highest local densities in two groups at R>3 Mpc matches the red fraction found in the two cores. Strikingly, galaxies at intermediate densities at R>3 Mpc, that are not group members, also show signs of an enhanced red fraction. Our results point to such intermediate density regions and the groups in the outskirts of the cluster, as sites where the local environment influences the transition of galaxies onto the red-sequence.Comment: 15 pages, 10 figures, 1 table, accepted for publication in ApJ, expanded introduction and additional references adde

    Complex-type N-glycan recognition by potent broadly neutralizing HIV antibodies

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    Broadly neutralizing HIV antibodies (bNAbs) can recognize carbohydrate-dependent epitopes on gp120. In contrast to previously characterized glycan-dependent bNAbs that recognize high-mannose N-glycans, PGT121 binds complex-type N-glycans in glycan microarrays. We isolated the B-cell clone encoding PGT121, which segregates into PGT121-like and 10-1074–like groups distinguished by sequence, binding affinity, carbohydrate recognition, and neutralizing activity. Group 10-1074 exhibits remarkable potency and breadth but no detectable binding to protein-free glycans. Crystal structures of unliganded PGT121, 10-1074, and their likely germ-line precursor reveal that differential carbohydrate recognition maps to a cleft between complementarity determining region (CDR)H2 and CDRH3. This cleft was occupied by a complex-type N-glycan in a “liganded” PGT121 structure. Swapping glycan contact residues between PGT121 and 10-1074 confirmed their importance for neutralization. Although PGT121 binds complex-type N-glycans, PGT121 recognized high-mannose-only HIV envelopes in isolation and on virions. As HIV envelopes exhibit varying proportions of high-mannose- and complex-type N-glycans, these results suggest promiscuous carbohydrate interactions, an advantageous adaptation ensuring neutralization of all viruses within a given strain

    Bose-Einstein Correlations of Three Charged Pions in Hadronic Z^0 Decays

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    Bose-Einstein Correlations (BEC) of three identical charged pions were studied in 4 x 10^6 hadronic Z^0 decays recorded with the OPAL detector at LEP. The genuine three-pion correlations, corrected for the Coulomb effect, were separated from the known two-pion correlations by a new subtraction procedure. A significant genuine three-pion BEC enhancement near threshold was observed having an emitter source radius of r_3 = 0.580 +/- 0.004 (stat.) +/- 0.029 (syst.) fm and a strength of \lambda_3 = 0.504 +/- 0.010 (stat.) +/- 0.041 (syst.). The Coulomb correction was found to increase the \lambda_3 value by \~9% and to reduce r_3 by ~6%. The measured \lambda_3 corresponds to a value of 0.707 +/- 0.014 (stat.) +/- 0.078 (syst.) when one takes into account the three-pion sample purity. A relation between the two-pion and the three-pion source parameters is discussed.Comment: 19 pages, LaTeX, 5 eps figures included, accepted by Eur. Phys. J.
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