372 research outputs found
Hypernovae and light dark matter as possible Galactic positron sources
The electron-positron annihilation source in the Galactic center region has
recently been observed with INTEGRAL/SPI, which shows that this 511 keV source
is strong and its extension is consistent with the Galactic bulge geometry. The
positron production rate, estimated to more than 10 per second, is very
high and raises a challenging question about the nature of the Galactic
positron source. Commonly considered astrophysical positron injectors, namely
type Ia supernovae are rare events and fall short to explain the observed
positron production rate. In this paper, we study the possibility of Galactic
positron production by hypernovae events, exemplified by the recently observed
SN2003dh/GRB030329, an asymmetric explosion of a Wolf-Rayet star associated
with a gamma-ray burst. In these kinds of events, the ejected material becomes
quickly transparent to positrons, which spread out in the interstellar medium.
Non radioactive processes, such as decays of heavy dark matter particles
(neutralinos) predicted by most extensions of the standard model of particle
physics, could also produce positrons as byproducts. However they are expected
to be accompanied by a large flux of high-energy gamma-rays, which were not
observed by EGRET and ground based Tcherenkov experiments. In this context we
explore the possibility of direct positron production by annihilation of light
dark matter particles.Comment: 8 pages, 0 figures, 35th COSPAR, accepted in July 2005 by Elsevier
Science for publication in "Advances in Space Research
The ECLAIRs telescope onboard the SVOM mission for gamma-ray burst studies
The X- and gamma-ray telescope ECLAIRs onboard the future mission for
gamma-ray burst studies SVOM (Space-based multi-band astronomical Variable
Objects Monitor) is foreseen to operate in orbit from 2013 on. ECLAIRs will
provide fast and accurate GRB triggers to other onboard telescopes, as well as
to the whole GRB community, in particular ground-based follow-up telescopes.
With its very low energy threshold ECLAIRs is particularly well suited for the
detection of highly redshifted GRB. The ECLAIRs X- and gamma-ray imaging camera
(CXG), used for GRB detection and localization, is combined with a soft X-ray
telescope (SXT) for afterglow observations and position refinement. The CXG is
a 2D-coded mask imager with a 1024 cm detection plane made of 8080
CdTe pixels, sensitive from 4 to 300 keV, with imaging capabilities up to about
120 keV and a localization accuracy better than 10 arcmin. The CXG permanently
observes a 2 sr-wide field of the sky and provides photon data to the onboard
science and triggering unit (UTS) which detects GRB by count-rate increases or
by the appearance of a new source in cyclic sky images. The SXT is a mirror
focusing X-ray telescope operating from 0.3 to 2 keV with a sensitivity of 1
mCrab for 100 s observations. The spacecraft slews within 3 min in
order to place the GRB candidate into the 2323 arcmin field of view
of the SXT, after which it refines the GRB position to about 10 arcsec. GRB
alerts are transmitted to ground-observers within tens of seconds via a VHF
network and all detected photons are available hours later for detailed
analysis. In this paper we present the ECLAIRs concepts, with emphasis on the
expected performances.Comment: on behalf of the ECLAIRs collaboration. Proceedings of Gamma-Ray
Bursts 2007 conference, Santa Fe, USA, 5-9 November 2007. Published in AIP
conf. proc. 1000, 581-584 (2008
Integral and Light Dark Matter
The nature of Dark Matter remains one of the outstanding questions of modern
astrophysics. The success of the Cold Dark Matter cosmological model argues
strongly in favor of a major component of the dark matter being in the form of
elementary particles, not yet discovered. Based on earlier theoretical
considerations, a possible link between the recent SPI/INTEGRAL measurement of
an intense and extended emission of 511 keV photons (positron annihilation)
from the central Galaxy, and this mysterious component of the Universe, has
been established advocating the existence of a light dark matter particle at
variance with the neutralino, in general considered as very heavy. We show that
it can explain the 511 keV emission mapped with SPI/INTEGRAL without
overproducing undesirable signals like high energy gamma-rays arising from
decays, and radio synchrotron photons emitted by high energy
positrons circulating in magnetic fields. Combining the annihilation line
constraint with the cosmological one (i.e. that the relic LDM energy density
reaches about 23% of the density of the Universe), one can restrict the main
properties of the light dark matter particle. Its mass should lie between 1 and
100 MeV, and the required annihilation cross section, velocity dependent,
should be significantly larger than for weak interactions, and may be induced
by the virtual production of a new light neutral spin 1 boson . On
astrophysical grounds, the best target to validate the LDM proposal seems to be
the observation by SPI/INTEGRAL and future gamma ray telescopes of the
annihilation line from the Sagittarius dwarf galaxy and the Palomar-13 globular
cluster, thought to be dominated by dark matter.Comment: 7 pages, 0 figures. To appear in the Proceedings of the 5th INTEGRAL
Workshop: "The INTEGRAL Universe", February 16-20, 2004, Munich, German
Continuum gamma-ray emission from light dark matter positrons and electrons
The annihilation of light dark matter was recently advocated as a possible
explanation of the large positron injection rate at the Galactic center deduced
from observations by the SPI spectrometer aboard INTEGRAL. The modelling of
internal Bremsstrahlung and in-flight annihilation radiations associated to
this process drastically reduced the mass range of this light dark matter
particle. We estimate critically the various energy losses and radiations
involved in the propagation of the positron before its annihilation --in-
flight or at rest.
Using a simple model with mono-energetic positrons injected and confined to
the Galactic bulge, we compute energy losses and gamma-ray radiations caused by
ionization, Bremsstrahlung interactions as well as in-flight and at rest
annihilation and compare these predictions to the available observations, for
various injection energies.
Confronting the predictions with observations by the CGRO/EGRET,
CGRO/COMPTEL, INTEGRAL/SPI and INTEGRAL/IBIS/ISGRI instruments, we deduce a
mass upper bound of 3 to 7.5 MeV/c^2 for the hypothetical light dark matter
particle. The most restrictive limit is in agreement with the value previously
found by Beacom and Yuksel and was obtained under similar assumptions, while
the 7.5 MeV/c^2 value corresponds to more conservative choices and to a
partially ionized propagation medium. We stress how the limit depends on the
degree of ionization of the propagation medium and how its precision could be
improved by a better appraisal of data uncertainties.Comment: Revision of the section dedicated to the observational
interpretation. 11 pages, 8 figures, 1 table. Accepted for publication in
Phys. Rev.
SVOM pointing strategy: how to optimize the redshift measurements?
The Sino-French SVOM mission (Space-based multi-band astronomical Variable
Objects Monitor) has been designed to detect all known types of gamma-ray
bursts (GRBs) and to provide fast and reliable GRB positions. In this study we
present the SVOM pointing strategy which should ensure the largest number of
localized bursts allowing a redshift measurement. The redshift measurement can
only be performed by large telescopes located on Earth. The best scientific
return will be achieved if we are able to combine constraints from both space
segment (platform and payload) and ground telescopes (visibility).Comment: Proceedings of Gamma-Ray Bursts 2007 conference, Santa Fe, USA, 5-9
November 2007. Published in AIP conf. proc. 1000, 585-588 (2008
Stereotactic body radiotherapy for recurrent hemoptysis due to chronic pulmonary aspergillosis: a case report and systematic review of the literature.
PURPOSE
Chronic pulmonary aspergillosis (CPA) can manifest as fungus balls in preexisting cavities of lung parenchyma and recurrent hemoptysis is among the most frequent complications. Radiotherapy can be considered for treatment-refractory aspergilloma and severe hemoptysis. To the best of our knowledge, we present the first application of stereotactic body radiotherapy (SBRT) for a pulmonary aspergilloma in a patient with limited functional lung capacity. The topic was further expanded on with a systematic review of the literature addressing the implementation of radiotherapy in CPA patients.
CASE REPORT
A 52-year-old man presented with recurring and treatment-refractory hemoptysis caused by chronic cavitary aspergillosis localized in the left lower lobe. We applied SBRT on two consecutive days with a total dose of 16âŻGy. Hemoptysis frequency decreased to a clinically insignificant level.
SYSTEMATIC REVIEW
We performed a systematic search of the literature in line with the PRISMA statement. The initial PubMed search resulted in 230 articles, of which 9 were included.
RESULTS
The available literature contained 35 patients with CPA who received radiotherapy. Dose fractionation usually ranged from 2 to 4âŻGy per fraction, applied almost exclusively in conventional two-dimensional (2D) techniques. There is no report of SBRT usage in such a scenario. Most cases report a positive treatment response after irradiation.
CONCLUSION
The presented case demonstrates long-term clinical stability after SBRT for recurrent hemoptysis due to pulmonary aspergilloma. The systematic literature search revealed that concept definition is still uncertain, and further work is necessary to establish radiotherapy in clinical practice
The ECLAIRs micro-satellite mission for gamma-ray burst multi-wavelength observations
Gamma-ray bursts (GRB), at least those with a duration longer than a few
seconds are the most energetic events in the Universe and occur at cosmological
distances. The ECLAIRs micro-satellite, to be launched in 2009, will provide
multi-wavelength observations of GRB, to study their astrophysics and to use
them as cosmological probes. Furthermore in 2009 ECLAIRs is expected to be the
only space borne instrument capable of providing a GRB trigger in near
real-time with sufficient localization accuracy for GRB follow-up observations
with the powerful ground based spectroscopic telescopes available by then. A
"Phase A study" of the ECLAIRs project has recently been launched by the French
Space Agency CNES, aiming at a detailed mission design and selection for flight
in 2006. The ECLAIRs mission is based on a CNES micro-satellite of the
"Myriade" family and dedicated ground-based optical telescopes. The satellite
payload combines a 2 sr field-of-view coded aperture mask gamma-camera using
6400 CdTe pixels for GRB detection and localization with 10 arcmin precision in
the 4 to 50 keV energy band, together with a soft X-ray camera for onboard
position refinement to 1 arcmin. The ground-based optical robotic telescopes
will detect the GRB prompt/early afterglow emission and localize the event to
arcsec accuracy, for spectroscopic follow-up observations.Comment: 7 pages, 1 figure, proceedings of the conference "New Developments in
Photodetection", Beaune (France), June 25005. Submitted to NIM-A (Elsevier
Science
The digital data processing concepts of the LOFT mission
The Large Observatory for X-ray Timing (LOFT) is one of the five mission
candidates that were considered by ESA for an M3 mission (with a launch
opportunity in 2022 - 2024). LOFT features two instruments: the Large Area
Detector (LAD) and the Wide Field Monitor (WFM). The LAD is a 10 m 2 -class
instrument with approximately 15 times the collecting area of the largest
timing mission so far (RXTE) for the first time combined with CCD-class
spectral resolution. The WFM will continuously monitor the sky and recognise
changes in source states, detect transient and bursting phenomena and will
allow the mission to respond to this. Observing the brightest X-ray sources
with the effective area of the LAD leads to enormous data rates that need to be
processed on several levels, filtered and compressed in real-time already on
board. The WFM data processing on the other hand puts rather low constraints on
the data rate but requires algorithms to find the photon interaction location
on the detector and then to deconvolve the detector image in order to obtain
the sky coordinates of observed transient sources. In the following, we want to
give an overview of the data handling concepts that were developed during the
study phase.Comment: Proc. SPIE 9144, Space Telescopes and Instrumentation 2014:
Ultraviolet to Gamma Ray, 91446
Effect of dose to parotid ducts on Sticky Saliva and Xerostomia in radiotherapy of head and neck squamous cell carcinoma.
BACKGROUND
Radiotherapy (RT) in head and neck squamous cell cancer (HNSCC) often leads to sticky saliva and xerostomia (SSX). Dose sparing of salivary glands (SG) reduces occurrence of SSX but few studies investigated the relationship between RT dose to SG substructures and SSX. We therefore investigated this hypothesis, focusing on the parotid duct (PD).
METHODS
Retrospective data was collected from 99 HNSCC patients treated at our center with (chemo-)radiotherapy (CRT). PD and other organs-at-risk (OAR) were (re-)contoured and DVHs were generated without re-planning. SSX was graded according to CTCAE v.4.03 and evaluated at acute, subacute, and two late timepoints.
RESULTS
Most patients presented with loco-regionally advanced disease. In 47% of patients, up-front neck dissection preceded CRT. Weighted mean dose was 28.6Â Gy for bilateral parotid glands (PG), and 32.0Â Gy for PD. Acute SSX presented as grades 0 (35.3%), I (41.4%), II (21.2%) and III (2.0%). There was no association of OARs and SSXââ„âgrade 2 in univariable logistic regression (LR). Multivariable LR showed statistically significant relationship of acute SSX with: PG weighted mean dose (OR 0.84, pâ=â0.004), contralateral PG mean dose (OR 1.14, pâ=â0.02) and contralateral PD planning OAR (PD PRV) mean dose (OR 1.84, pâ=â0.03).
CONCLUSIONS
There was an association of acute SSX with dose exposure of PD PRV in multivariable regression, only. Due to statistical uncertainties and the retrospective nature of this analysis, further studies are required to confirm or reject the hypothesis
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