A SPATIAL MODEL OF REGIONAL VARIATIONS IN EMPLOYMENT GROWTH IN APPALACHIA

In this study, a spatial equilibrium model of employment growth is developed and empirically estimated by Generalized Spatial Two-Stage Least Squares (GS2SLS) estimator using cross-sectional data from Appalachian counties for 1990-2000. Besides the existence of spatial spillover effects, the results suggest that agglomerative effects that arise from the demand and the supply side contribute to employment growth in the study area during the study period. The policy implications of the findings are: (1) Regional cooperation of counties and communities is advisable and may in fact be necessary to design effective policies to encourage employment growth; and (2) Policy makers at the county level may need to design policies that can attract people with high endowments of human capital and higher income into their respective counties.APPALACHIA, EMPLOYMENT GROWTH, SPATIAL MODEL

A Spatial Panel Simultaneous-Equations Model of Business Growth, Migration Behavior, Local Public Services and Household Income in Appalachia

In this paper we develop a spatial panel simultaneous-equations model of business growth, migration behavior, local public services and median household income in a partial lag-adjustment growth-equilibrium framework and utilizing a one-way error component model for the disturbances. This model is an extension of the jobs follow people or people follow jobs literature and it improved previous models in the growth-equilibrium tradition by: (1) explicitly modeling local government and regional income in the growth process; (2) explicitly modeling gross in-migration and gross out-migration separately in order to spell out the differential effects, which used to be glossed over under net population change in previous studies; (3) explicitly incorporating both spatially lagged dependent variables and spatially lagged error terms to account for spatial spillover effects in the data set; and (4) extending and generalizing the modeling and estimation of simultaneous systems of spatially interrelated cross sectional equations into a panel data setting. To estimate the model, we develop a five-step new estimation strategy by generalizing the Generalized Spatial Three-Stage Least Squares (GS3SLS) approach outlined in Kelejian and Prucha (2004) into a panel data setting. The empirical implementation of the model uses county-level data from the 418 Appalachian counties for 1980-2000. Generally, the results from these model estimations are consistent with the theoretical expectations and empirical findings in the equilibrium growth literature and provide support to the basic hypotheses of this study. First, the estimates show the existence of feedback simultaneities among the endogenous variables of the model. Second, the results also show the existence of conditional convergence with respect to the respective endogenous variable of each equation of the model and the speed of adjustment parameters are generally comparable to those in literature. Third, the results from the parameter estimation of the model indicate the existence of spatial autoregressive lag effects and spatial cross-regressive lag effects with respect to the endogenous variables of the model. One of the key conclusions is that sector specific policies should be integrated and harmonized in order to give the desirable outcome. Besides, regionally focusing resources for development policy may yield greater returns than treating all locations the same.Community/Rural/Urban Development,

Notch-dependent Fizzy-related/Hec1/Cdh1 expression is required for the mitotic-to-endocycle transition in Drosophila follicle cells.

AbstractDuring Drosophila oogenesis, Notch function regulates the transition from mitotic cell cycle to endocycle in follicle cells at stage 6 [1, 2]. Loss of either Notch function or its ligand Delta (Dl) disrupts the normal transition; this disruption causes mitotic cycling to continue and leads to an overproliferation phenotype [1, 2]. In this context, the only known cell cycle component that responds to the Notch pathway is String/Cdc25 (Stg), a G2/M cell cycle regulator [1]. We found that prolonged expression of string is not sufficient to keep cells efficiently in mitotic cell cycle past stage 6, suggesting that Notch also regulates other cell cycle components in the transition. By using an expression screen, we found such a component: Fizzy-related/Hec1/Cdh1 (Fzr), a WD40 repeat protein. Fzr regulates the anaphase-promoting complex/cyclosome (APC/C) and is expressed at the mitotic-to-endocycle transition in a Notch-dependent manner. Mutant clones of Fzr revealed that Fzr is dispensable for mitosis but essential for endocycles. Unlike in Notch clones, in Fzr mutant cells mitotic markers are absent past stage 6. Only a combined reduction of Fzr and ectopic Stg expression prolongs mitotic cycles in follicle cells, suggesting that these two cell cycle regulators, Fzr and Stg, are important mediators of the Notch pathway in the mitotic-to-endocycle transition

A Spatial Model of Regional Variations in Business Growth in Appalachian States

In this study, a spatial growth equilibrium model of business growth is developed and empirically estimated by Generalized Spatial Two-Stage Least Squares (GS2SLS) estimator using cross-sectional data from Appalachian States counties for 1990-2000. Beside the existence of spatial spillover effects, the results suggest that agglomerative effects that arise from both the demand and the supply sides were active in contributing to business growth in the study area during the study period. The policy implications of these findings are: (1) Regional cooperation of counties and communities is advisable and may even in fact be necessary to design appropriate policies that encourage business growth; and (2) Policy makers at the county level may need to design policies that can attract people with high endowment of human capital and higher income into their respective counties

An Empirical Analysis of Employment, Migration, Local Public Services and Regional Income Growth in Appalachia

This study develops a five-equation simultaneous system in a partial lagadjustment growth-equilibrium framework. It improved previous models in the growthequilibrium tradition by explicitly modeling local government and regional income in the growth process. It also explicitly modeled gross in-migration and gross out-migration separately in order to spell out the differential effects. The results show the existence of feedback simultaneities among the endogenous variables of the model. This finding is important from economic policy perspective because it indicates that sector specific policies should be integrated and harmonized in order to achieve the desirable outcome. Under this circumstance, looking at the direct plus indirect impacts of a change in a given policy is important

A Spatial Panel Simultaneous-Equations Model of Business Growth, Migration Behavior, Local Public Services and Household Income in Appalachia

In this paper we develop a spatial panel simultaneous-equations model of business growth, migration behavior, local public services and median household income in a partial lag-adjustment growth-equilibrium framework and utilizing a one-way error component model for the disturbances. This model is an extension of the “jobs follow people or people follow jobs” literature and it improved previous models in the growth-equilibrium tradition by: (1) explicitly modeling local government and regional income in the growth process; (2) explicitly modeling gross in-migration and gross out-migration separately in order to spell out the differential effects, which used to be glossed over under net population change in previous studies; (3) explicitly incorporating both spatially lagged dependent variables and spatially lagged error terms to account for spatial spillover effects in the data set; and (4) extending and generalizing the modeling and estimation of simultaneous systems of spatially interrelated cross sectional equations into a panel data setting. To estimate the model, we develop a five-step new estimation strategy by generalizing the Generalized Spatial Three-Stage Least Squares (GS3SLS) approach outlined in Kelejian and Prucha (2004) into a panel data setting. The empirical implementation of the model uses county-level data from the 418 Appalachian counties for 1980-2000. Generally, the results from these model estimations are consistent with the theoretical expectations and empirical findings in the equilibrium growth literature and provide support to the basic hypotheses of this study. First, the estimates show the existence of feedback simultaneities among the endogenous variables of the model. Second, the results also show the existence of conditional convergence with respect to the respective endogenous variable of each equation of the model and the speed of adjustment parameters are generally comparable to those in literature. Third, the results from the parameter estimation of the model indicate the existence of spatial autoregressive lag effects and spatial cross-regressive lag effects with respect to the endogenous variables of the model. One of the key conclusions is that sector specific policies should be integrated and harmonized in order to give the desirable outcome. Besides, regionally focusing resources for development policy may yield greater returns than treating all locations the same

The Vlasov limit and its fluctuations for a system of particles which interact by means of a wave field

In two recent publications [Commun. PDE, vol.22, p.307--335 (1997), Commun. Math. Phys., vol.203, p.1--19 (1999)], A. Komech, M. Kunze and H. Spohn studied the joint dynamics of a classical point particle and a wave type generalization of the Newtonian gravity potential, coupled in a regularized way. In the present paper the many-body dynamics of this model is studied. The Vlasov continuum limit is obtained in form equivalent to a weak law of large numbers. We also establish a central limit theorem for the fluctuations around this limit.Comment: 68 pages. Smaller corrections: two inequalities in sections 3 and two inequalities in section 4, and definition of a Banach space in appendix A1. Presentation of LLN and CLT in section 4.3 improved. Notation improve

Trapped and excited w modes of stars with a phase transition and R>=5M

The trapped $w$-modes of stars with a first order phase transition (a density discontinuity) are computed and the excitation of some of the modes of these stars by a perturbing shell is investigated. Attention is restricted to odd parity (``axial'') $w$-modes. With $R$ the radius of the star, $M$ its mass, $R_{i}$ the radius of the inner core and $M_{i}$ the mass of such core, it is shown that stars with $R/M\geq 5$ can have several trapped $w$-modes, as long as $R_{i}/M_{i}<2.6$. Excitation of the least damped $w$-mode is confirmed for a few models. All of these stars can only exist however, for values of the ratio between the densities of the two phases, greater than $\sim 46$. We also show that stars with a phase transition and a given value of $R/M$ can have far more trapped modes than a homogeneous single density star with the same value of $R/M$, provided both $R/M$ and $R_{i}/M_{i}$ are smaller than 3. If the phase transition is very fast, most of the stars with trapped modes are unstable to radial oscillations. We compute the time of instability, and find it to be comparable to the damping of the $w$-mode excited in most cases where $w$-mode excitation is likely. If on the other hand the phase transition is slow, all the stars are stable to radial oscillations.Comment: To appear in Physical Review

Orientifolds and the Refined Topological String

We study refined topological string theory in the presence of orientifolds by counting second-quantized BPS states in M-theory. This leads us to propose a new integrality condition for both refined and unrefined topological strings when orientifolds are present. We define the SO(2N) refined Chern-Simons theory which computes refined open string amplitudes for branes wrapping Seifert three-manifolds. We use the SO(2N) refined Chern-Simons theory to compute new invariants of torus knots that generalize the Kauffman polynomials. At large N, the SO(2N) refined Chern-Simons theory on the three-sphere is dual to refined topological strings on an orientifold of the resolved conifold, generalizing the Gopakumar-Sinha-Vafa duality. Finally, we use the (2,0) theory to define and solve refined Chern-Simons theory for all ADE gauge groups

Response of a Hexagonal Granular Packing under a Localized External Force: Exact Results

We study the response of a two-dimensional hexagonal packing of massless, rigid, frictionless spherical grains due to a vertically downward point force on a single grain at the top layer. We use a statistical approach, where each mechanically stable configuration of contact forces is equally likely. We show that this problem is equivalent to a correlated $q$-model. We find that the response is double-peaked, where the two peaks, sharp and single-grain diameter wide, lie on the two downward lattice directions emanating from the point of the application of the external force. For systems of finite size, the magnitude of these peaks decreases towards the bottom of the packing, while progressively a broader, central maximum appears between the peaks. The response behaviour displays a remarkable scaling behaviour with system size $N$: while the response in the bulk of the packing scales as $\frac{1}{N}$, on the boundary it is independent of $N$, so that in the thermodynamic limit only the peaks on the lattice directions persist. This qualitative behaviour is extremely robust, as demonstrated by our simulation results with different boundary conditions. We have obtained expressions of the response and higher correlations for any system size in terms of integers corresponding to an underlying discrete structure.Comment: Accepted for publication in JStat; 33 pages, 10 figures; Section 2.2 reorganized and rewritten; Details about the simulation procedure added in Sec.3.1. ; A new section, summarizing the final results and the calculation procedure adde