2,696 research outputs found

    Chemical weed control in grain sorghum

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    "Federal regulations on the use of herbicides change frequently, so stay informed on the status of label registration. To the best of our knowledge, this guidesheet conforms to laws and regulations at the time of writing."--First page.James A. Schaeffer, Harold D. Kerr, David Guethle, O. Hale Fletchall, E.J. Peters, L.E. Anderson, and Zane R. Helsel (Department of Agronomy, College of AGriculture)Revised 1/85/10

    Herbicides for grain sorghum 1984

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    "Federal regulations on the use of herbicides change frequently, so stay informed on the status of label registration. To the best of our knowledge, this guidesheet conforms to laws and regulations at the time of writing."--First page.James A. Schaeffer, Harold D. Kerr, David Guethle, O. Hale Fletchall, E.J. Peters, L.E. Anderson, and Zane R. Helsel (Department of Agronomy, College of AGriculture)Revised 1/84/10

    Interferon β-1a in relapsing multiple sclerosis: four-year extension of the European IFNβ-1a Dose-C omparison Study

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    Background: Multiple sclerosis (MS) is a chronic disease requiring long-term monitoring of treatment. Objective: To assess the four-year clinical efficacy of intramuscular (IM) IFNb-1a in patients with relapsing MS from the European IFNb-1a Dose-C omparison Study. Methods: Patients who completed 36 months of treatment (Part 1) of the European IFNb-1a Dose-C omparison Study were given the option to continue double-blind treatment with IFNb-1a 30 mcg or 60 mcg IM once weekly (Part 2). Analyses of 48-month data were performed on sustained disability progression, relapses, and neutralizing antibody (NA b) formation. Results: O f 608/802 subjects who completed 36 months of treatment, 493 subjects continued treatment and 446 completed 48 months of treatment and follow-up. IFNb-1a 30 mcg and 60 mcg IM once weekly were equally effective for up to 48 months. There were no significant differences between doses over 48 months on any of the clinical endpoints, including rate of disability progression, cumulative percentage of patients who progressed (48 and 43, respectively), and annual relapse rates; relapses tended to decrease over 48 months. The incidence of patients who were positive for NAbs at any time during the study was low in both treatment groups. Conclusion: C ompared with 60-mcg IM IFNb-1a once weekly, a dose of 30 mcg IM IFNb-1a once weekly maintains the same clinical efficacy over four years

    The velocity and mass distribution of clusters of galaxies from the CNOC1 cluster redshift survey

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    In the context of the CNOC1 cluster survey, redshifts were obtained for galaxies in 16 clusters. The resulting sample is ideally suited for an analysis of the internal velocity and mass distribution of clusters. Previous analyses of this dataset used the Jeans equation to model the projected velocity dispersion profile. However, the results of such an analysis always yield a strong degeneracy between the mass density profile and the velocity dispersion anisotropy profile. Here we analyze the full (R,v) dataset of galaxy positions and velocities in an attempt to break this degeneracy. We build an `ensemble cluster' from the individual clusters under the assumption that they form a homologous sequence. To interpret the data we study a one-parameter family of spherical models with different constant velocity dispersion anisotropy. The best-fit model is sought using a variety of statistics, including the overall likelihood of the dataset. Although the results of our analysis depend slightly on which statistic is used to judge the models, all statistics agree that the best-fit model is close to isotropic. This result derives primarily from the fact that the observed grand-total velocity histogram is close to Gaussian, which is not expected to be the case for a strongly anisotropic model. The best-fitting models have a mass-to-number-density ratio that is approximately independent of radius over the range constrained by the data. They also have a mass-density profile that is consistent with the dark matter halo profile advocated by Navarro, Frenk & White, in terms of both the profile shape and the characteristic scale length. This adds important new weight to the evidence that clusters do indeed follow this proposed universal mass density profile. [Abridged]Comment: 37 pages, LaTeX, with 11 PostScript figures. Accepted by the Astronomical Journal, to appear in the May 2000 issue. This replacement version contains an additional Appendix and one additional Figure with respect to the version submitted to astro-ph originall

    The Grizzly, April 12, 2018

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    The Distance Between Us : Ursinus Welcomes Mexican-American Author Reyna Grande • Lantern Launch Celebrates All Things Creative About Ursinus • Berman Museum Opens Annual Student Exhibition • International Perspective: Easter Festivities in Prague Recall Student\u27s Childhood Celebrations • Senior Awarded Fulbright Scholarship • Students Present at Celebration of Student Achievement • Summer Looks Bright for Dr. Lori Daggar • Opinions: Ursinus Needs More Science Labs for Humanities Students; Facebook\u27s Data Scandal Reveals Need for Privacy Protection • Men\u27s Lax Maintains Optimism Amid Rocky Season • T&F Impresses in Outdoor Openerhttps://digitalcommons.ursinus.edu/grizzlynews/1644/thumbnail.jp

    On the cosmological mass function theory

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    This paper provides, from one side, a review of the theory of the cosmological mass function from a theoretical point of view, starting from the seminal paper of Press & Shechter (1974) to the last developments (Del Popolo & Gambera (1998, 1999), Sheth & Tormen 1999 (ST), Sheth, Mo & Tormen 2001 (ST1), Jenkins et al. 2001 (J01), Shet & Tormen 2002 (ST2), Del Popolo 2002a, Yagi et al. 2004 (YNY)), and from another side some improvements on the multiplicity function models in literature. ...Comment: Astronomy Reports, in prin

    Oral rehydration therapies in Senegal, Mali, and Sierra Leone: A spatial analysis of changes over time and implications for policy

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    Background: Oral rehydration solution (ORS) is a simple intervention that can prevent childhood deaths from severe diarrhea and dehydration. In a previous study, we mapped the use of ORS treatment subnationally and found that ORS coverage increased over time, while the use of home-made alternatives or recommended home fluids (RHF) decreased, in many countries. These patterns were particularly striking within Senegal, Mali, and Sierra Leone. It was unclear, however, whether ORS replaced RHF in these locations or if children were left untreated, and if these patterns were associated with health policy changes.Methods: We used a Bayesian geostatistical model and data from household surveys to map the percentage of children with diarrhea that received (1) any ORS, (2) only RHF, or (3) no oral rehydration treatment between 2000 and 2018. This approach allowed examination of whether RHF was replaced with ORS before and after interventions, policies, and external events that may have impacted healthcare access.Results: We found that RHF was replaced with ORS in most Sierra Leone districts, except those most impacted by the Ebola outbreak. In addition, RHF was replaced in northern but not in southern Mali, and RHF was not replaced anywhere in Senegal. In Senegal, there was no statistical evidence that a national policy promoting ORS use was associated with increases in coverage. In Sierra Leone, ORS coverage increased following a national policy change that abolished health costs for children.Conclusions: Children in parts of Mali and Senegal have been left behind during ORS scale-up. Improved messaging on effective diarrhea treatment and/or increased ORS access such as through reducing treatment costs may be needed to prevent child deaths in these areas

    The serine protease hepsin mediates urinary secretion and polymerisation of Zona Pellucida domain protein uromodulin.

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    Uromodulin is the most abundant protein in the urine. It is exclusively produced by renal epithelial cells and it plays key roles in kidney function and disease. Uromodulin mainly exerts its function as an extracellular matrix whose assembly depends on a conserved, specific proteolytic cleavage leading to conformational activation of a Zona Pellucida (ZP) polymerisation domain. Through a comprehensive approach, including extensive characterisation of uromodulin processing in cellular models and in specific knock-out mice, we demonstrate that the membrane-bound serine protease hepsin is the enzyme responsible for the physiological cleavage of uromodulin. Our findings define a key aspect of uromodulin biology and identify the first in vivo substrate of hepsin. The identification of hepsin as the first protease involved in the release of a ZP domain protein is likely relevant for other members of this protein family, including several extracellular proteins, as egg coat proteins and inner ear tectorins

    A Statistical Test of Heterogeneous Subgraph Densities to Assess Clusterability

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    Determining if a graph displays a clustered structure prior to subjecting it to any cluster detection technique has recently gained attention in the literature. Attempts to group graph vertices into clusters when a graph does not have a clustered structure is not only a waste of time; it will also lead to misleading conclusions. To address this problem, we introduce a novel statistical test, the-test, which is based on comparisons of local and global densities. Our goal is to assess whether a given graph meets the necessary conditions to be meaningfully summarized by clusters of vertices. We empirically explore our test’s behavior under a number of graph structures. We also compare it to other recently published tests. From a theoretical standpoint, our test is more general, versatile and transparent than recently published competing techniques. It is based on the examination of intuitive quantities, applies equally to weighted and unweighted graphs and allows comparisons across graphs. More importantly, it does not rely on any distributional assumptions, other than the universally accepted definition of a clustered graph. Empirically, our test is shown to be more responsive to graph structure than other competing tests
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