Reliability and validity of the Morisky Medication Adherence Scale for bipolar mood disorder

WOS: 000334279100007Objective: The aim of the present study is to adapt the Morisky Medication Adherence Scale (MMAS) to Turkish, examine the reliability and validity of the scale among bipolar mood disorder patients and examine the relationship between mood stabilizers' blood drug levels and adherence to treatment. Methods: The sample comprised 59 bipolar mood disorder (BMD) patients in Gaziantep University Sahinbey Research and Practice Hospital Psychiatry Department Mood Disorder Clinic, who met the study requirements and who was diagnosed with BMD. The inclusion criterion for patients was to be euthymic at the time of the study. After examining the linguistic equivalence of the scale, its reliability and validity were assessed. Internal consistency and test-retest reliability were performed for reliability analysis; factor analysis was performed in order to determine construct validity, and Kappa agreement analysis was performed for external validity. Results: The internal consistency coefficient of the scale was found to be 0.62 while test-retest reliability coefficients were found to range between 0.64 and 0.96. In factor analysis, the KMO value was found to be 0.636; Bartlett's test result was found to be 29.312 and the items intercorrelated with each other. It was also found out that most of the variables had common features, loaded on a single factor and the total variance rate of the scale had a sufficient value. Responses of patients' relatives and patients' blood drug levels were taken as criterion for external validity and a statistically significant agreement was found between these criteria and patients' MMAS. Conclusion: On the basis of these results, it was concluded that MMAS is a valid and reliable measurement instrument for bipolar disorder and is recommended to be used in the clinic and research

Evaluation of the accuracy of Lachman and Anterior Drawer Tests with KT1000 in the follow-up of anterior cruciate ligament surgery

WOS: 000446917800017PubMed: 27656635Ligament laxity measurement is clinically valuable to diagnose the injury and also to compare the laxity before and after surgical procedure. The aim of the study was to compare the accuracy of the Lachman and Anterior Drawer Tests to evaluate the knee examination with the KT1000 arthrometer after the anterior cruciate ligament (ACL) surgery in early follow-up period. Fourty ACL reconstructed knees were examined with the Lachman and Anterior Drawer Tests, and KT1000 arthrometer with compariable intact knee of the same patients. Physical emanination findings were compared with the KT1000 arthrometer with each power. Spearman correlation and receiver operating characteristic (ROC) analysis were used for the evaluation of relations between parameters. Significance was evaluated in P<0.1 and P<0.05. The mean age was 28.18 +/- 6.21 yr, and the mean follow-up was 23.09 +/- 9.08 months. The mean KT1000 measurements of 40 operated knees state at 6.8, 9.1, 13.6 kg and maxium anterior displacement forces were 4.9, 6.7, 8.7, and 11.9 mm, respectively. The same values for the same acting forces of intact knees were 4.2, 5.9, 7.8, and 10.2, respectively. In Spearman's correlation and ROC analysis at 13.6-kg power on KT1000 arthrometer statistically matched with pyhsical examinations (P<0.1, P<0.01). In our study, correlation of physical examinations with KT1000 arthrometer is a worthy evaluation technique that can be added to examination of ACL reconstructed knee to control with inexperinced examiners' findings. We suggest that at 13.6-kg power with KT1000 arthrometer findings perfectly match the Lachman and Anterior Drawer Tests of the knee

Is anterior cruciate ligament surgery technique important in rehabilitation and activity scores?

WOS: 000446917300016PubMed: 27419120To compare the two different anterior cruciate ligament surgery techniques' effect in rehabilitation and activity performance. Fifty-five patients were evaluated. Twenty-seven patients with transtibial technique (TT), 28 with anatomic single-bundle technique (AT) included. Tegner Activity Scale (TAS) was performed at preoperation and follow-up. The returning time of the sport and work was evaluated at follow-up. Single-leg hop test was performed at follow-up. Outcomes were compared between the two groups. The determined length difference between the operated knee and the intact knee was compared between the two groups. Average age of TT and AT was 27.9 +/- 6.4 yr, 28.3 +/- 6 yr, respectively. There was a significant difference between the two groups in duration of returning to sport. 7 group had higher duration to return to sport (P 0.05). There was a significant difference between the two groups. 7 group had significantly higher values than AT group (P 0.05). The increase of TAS in patients who had AT was higher than the patients who had TT (P> 0.05). No difference in single-leg hop test at 55%-65%, 65%-75%, and 85%-95% level (P> 0.05). In this test at 75%-85% TT group had higher values than AT group (P< 0.05), AT group had higher values at 95%-105% level (P<0.05). Good short and long-term knee outcome scores depend on rehabilitation protocol after surgery. Surgery technique should provide the adequate stability in rehabilitation period. AT obtains better outcomes in rehabilitation

Neuroleptic malignant syndrome induced by ziprasidone on the second day of treatment: A case report [2]

Abstract Not Availabl

Surgical treatment of dorsal perilunate fracture-dislocations and prognostic factors

WOS: 000366662600012PubMed: 26542987Introduction: Perilunate injuries are rare entities which can be difficult to diagnose. Most common type is dorsal perilunate fracture dislocation (97%). The purpose of treatment is anatomic reduction and stable fixation. We aimed to present the radiologic and functional results of surgically treated dorsal perilunate fracture-dislocations and discuss the factors influencing the prognosis. Methods: Between 2007 and 2013, 17 patients were operated for perilunate fracture-dislocations. The mechanism of injuries, soft tissue traumas, etiologic factors and stages according to Herzberg classification were determined. The MAYO wrist score was used for functional evaluation. Scapholunate distance and scapholunate angle were measured and, degenerative changes were investigated by comparing with contralateral side on plain x-ray images in terms of radiologic evaluation. Results: Mean follow-up was 37,8 (range, 16-84) months. The average age at surgery was 35.1 (range, 18-51) years. Fifteen patients were male and two were female. Functional results were excellent in four (23.5%), good in two (11.8%), satisfactory in five (29.4%) and poor in six (35.3%) patients. Degenerative changes were determined in radiocarpal and mid-carpal joints of 14 wrists (82.4%). Scapholunate dissociation more than 2 mm was detected in three wrists. In four wrists osteochondral fragments were determined on the head of the capitate. Stage 2 lesions, delayed presentations, open fractures, scapholunate dissociations more than 2 mm had worse functional results. Conclusion: Despite anatomic reduction, ligamentous and chondral injuries that occured at the time of trauma may cause persistant wrist pain in patients who suffer perilunate fracture dislocation. Mechanism of injury, presence of soft tissue defects and the time between injury and treatment can affect clinical and radiologic results. (C) 2015 IJS Publishing Group Limited. Published by Elsevier Ltd. All rights reserved

Symptomatic Remission Determines Functional Improvement and Quality of Life in Schizophrenia

WOS: 000391572500008PubMed: 28360807Introduction: Schizophrenia is a chronic illness that negatively affects the quality of life and psychosocial functions. Defined criteria to assess remission in schizophrenia are considered to be useful in the longterm follow-up of patients and in discriminating diagnostic factors. This study investigated the quality of life and functionality in schizophrenia patients in symptomatic remission (R-Sch) and not in remission (NonR- Sch). Methods: Sociodemographic data were collected for 40 R-Sch and 40 Non-R-Sch patients, and the following scales were administered: the Clinical Global Impression-Severity (CGI-S) Scale; Positive and Negative Syndrome Scale (PANSS), World Health Organization Quality of Life Questionnaire-Short Form, Turkish Version (WHOQOL-BREF-TR), Quality of Life Scale for Schizophrenia Patients (QLS), and Global Assessment of Functioning Scale (GAF). Results: the total and all subscale scores of PANSS and the CGI-S score were significantly lower in the R-Sch group than in the NonR- Sch group, whereas the GAF scores and all subscales of QLS and WHOQOL-BREF-TR were significantly higher. Conclusion: This study demonstrates that improvement in symptoms in schizophrenia patients improves quality and functionality in all areas of life, suggesting that an improvement in symptoms is the most important determinant of functional recovery in the treatment of schizophrenia

High ceruloplasmin levels are associated with obsessive compulsive disorder: a case control study

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A Magnetic Resonance Imaging Study of the Corpus Callosum Volume in Schizophrenia

Conclusion: Corpus callosum volume was significantly reduced in schizophrenic group. Evidence of reduced interhemispheric communication in schizophrenia may be important in explaining the associations between the abnormalities of midline brain structures with the psychiatric illness