49 research outputs found
Dark Matter directional detection: comparison of the track direction determination
Several directional techniques have been proposed for a directional detection
of Dark matter, among others anisotropic crystal detectors, nuclear emulsion
plates, and low-pressure gaseous TPCs. The key point is to get access to the
initial direction of the nucleus recoiling due to the elastic scattering by a
WIMP. In this article, we aim at estimating, for each method, how the
information of the recoil track initial direction is preserved in different
detector materials. We use the SRIM simulation code to emulate the motion of
the first recoiling nucleus in each material. We propose the use of a new
observable, D, to quantify the preservation of the initial direction of the
recoiling nucleus in the detector. We show that in an emulsion mix and an
anisotropic crystal, the initial direction is lost very early, while in a
typical TPC gas mix, the direction is well preserved.Comment: 9 pages, 5 figure
Dark Matter Directionality Detection performance of the Micromegas-based TPC-MIMAC detector
Directional Dark Matter Detection (DDMD) can open a new signature for Weakly
Massive Interacting Particles (WIMPs) Dark Matter. The directional signature
provides in addition, an unique way to overcome the neutron and neutrino
backgrounds. In order to get the directional signature, the DDM detectors
should be sensitive to low nuclear energy recoils in the keV range and have an
angular resolution better than . We have performed experiments with
low energy () ion beam facilities to measure the angular
distribution of nuclear recoil tracks in a MIMAC detector prototype. In this
paper, we study angular spreads with respect to the electron drift direction
( incident angle) of Fluorine nuclear tracks in this low energy
range, and show nuclear recoil angle reconstruction produced by a monoenergetic
neutron field experiment. We find that a high-gain systematic effect leads to a
high angular resolution along the electron drift direction. The measured
angular distribution is impacted by diffusion, and space charge or ion feedback
effects, which can be corrected for by an asymmetry factor observed in the
flash-ADC profile. The estimated angular resolution of the incident
ion is better than at keV kinetic energy and agrees with the
simulations within %. The distributions from the nuclear recoils have been
compared with simulated results based on a modified Garfield++ code. Our study
shows that protons would be a more adapted target than heavier nuclei for DDMD
of light WIMPs. We demonstrate that directional signature from the Galactic
halo origin of a Dark Matter WIMP signal is experimentally achievable, with a
deep understanding of the operating conditions of a low pressure detector with
its diffusion mechanism.Comment: 19 pages, 12 figure
Theoretical approach based on Monte-Carlo simulations to predict the cell survival following BNCT
International audienceWe present here a very preliminary work on BNCT Dosimetry. The approach is as follows:A full Monte Carlo calculation is used to separate all dose components and determine the corresponding physical dose fractions with a realistic clinical model.These dose fractions are then used as mixed fields to predict cell-survivals and RBE values for a specific cell-line, thanks to the radiobiological model NanOxTM
Development and Characterisation of Gastroretentive Solid Dosage Form Based on Melt Foaming
Dosage forms with increased gastric residence time are promising tools to increase bioavailability of drugs with narrow absorption window. Low-density floating formulations could avoid gastric emptying; therefore, sustained drug release can be achieved. Our aim was to develop a new technology to produce low-density floating formulations by melt foaming. Excipients were selected carefully, with the criteria of low gastric irritation, melting range below 70°C and well-known use in oral drug formulations. PEG 4000, Labrasol and stearic acid type 50 were used to create metronidazole dispersion which was foamed by air on atmospheric pressure using in-house developed apparatus at 53°C. Stearic acid was necessary to improve the foamability of the molten dispersion. Additionally, it reduced matrix erosion, thus prolonging drug dissolution and preserving hardness of the moulded foam. Labrasol as a liquid solubiliser can be used to increase drug release rate and drug solubility. Based on the SEM images, metronidazole in the molten foam remained in crystalline form. MicroCT scans with the electron microscopic images revealed that the foam has a closed-cell structure, where spherical voids have smooth inner wall, they are randomly dispersed, while adjacent voids often interconnected with each other. Drug release from all compositions followed Korsmeyer-Peppas kinetic model. Erosion of the matrix was the main mechanism of the release of metronidazole. Texture analysis confirmed that stearic acid plays a key role in preserving the integrity of the matrix during dissolution in acidic buffer. The technology creates low density and solid matrix system with micronsized air-filled voids
A portable and directional fast neutron detector: MIMAC fastN
International audienc
MIMAC-FASTn : a fast neutron spectrometer
International audienc
Strategies for a directional detection of Dark Matter
International audienc