New BN coating on SiC fibers as the interphase of SiC/SiC composites

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ショウジョウバエ野外集団におけるコアプロモーター配列変異によって生じる発現量変化への自然選択

要約のみTohoku University河田雅圭課

Natural selection in a population of Drosophila melanogaster explained by changes in gene expression caused by sequence variation in core promoter regions

Estimated regions of linkage disequilibrium and associations between SNPs and expression level in regions flanking CPRs for which sequence variation could explain gene expression variation and was subject to purifying selection or selective sweep. Flanking regions (±5000 bp) of CPRs for CG15743 (A), CG9044 (B), brat (C), Cyp4d1 (D), CG14253 (E), Nmda1 (F), CG6950 (G), CG10463 (H), and CG33506 (I) are shown. Gray shades indicate haplotype blocks within which linkage disequilibrium could be found. Orange bars indicate coding region. Green bar indicates CPR. Each dot indicates a false discovery rate value (FDR) using the Wald test for the association between expression levels and SNPs. Horizontal line indicates FDR threshold (α = 0.01). (PDF 626 kb

Development of an Ultra High Resolution Scanning Electron Microscope by Means of a Field Emission Source and In-Lens System

An ultra high resolution scanning electron microscope, which is composed of a cold cathode field emission gun and an in-lens system for specimens, has been developed. Probe size is estimated 0.8nm at 30kV by calculation and confirmed experimentally using high atomic number samples such as fine Pt particles sputter-coated on carbon. Three stage ion pumps for the column and a turbo molecular pump for the specimen chamber have been used for a totally dry vacuum system. Applications for fine metal oxide particles and biological samples observed directly without any metal coating, and applications chosen especially to show lower voltage performance, are shown

Trigger digit after corticosteroid injection

Purpose: The aim of this study was to elucidate whether intrasynovial corticosteroid injections for trigger digit reduced the volume of the tendon and pulley on high-resolution ultrasonography. Methods: Twenty-three digits of 20 patients with trigger digit were included. Each affected finger was graded clinically according to the following classification: grade I for pre-triggering, grade II for active triggering, grade III for passive triggering, and grade IV for presence of contracture. Axial ultrasound examinations were performed before an intrasynovial corticosteroid injection and at an average of 31 days after the injection. The transverse diameter, thickness, and cross-sectional area of the tendon and the thickness of the pulley were measured by two independent, blinded researchers. Results: At least 1 grade of improvement was achieved in this study group by the time of the second examination. The transverse diameter and cross-sectional area of the tendon and the thickness of the pulley significantly decreased (P<0.05). Conclusion: The injection of a single dose of betamethasone improved clinical symptoms by reducing the volume of both the tendon and pulley, which may be related to the fact that tendon and pulley ruptures are delayed by corticosteroid injections

Measurement method of in-situ tensile strength of SiC fiber in SiC/SiC composite

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Evaluation of the histological and mechanical features of tendon healing in a rabbit model

Objectives This study aimed to evaluate the histological and mechanical features of tendon healing in a rabbit model with second-harmonic-generation (SHG) imaging and tensile testing. Materials and Methods A total of eight male Japanese white rabbits were used for this study. The flexor digitorum tendons in their right leg were sharply transected, and then were repaired by intratendinous stitching. At four weeks post-operatively, the rabbits were killed and the flexor digitorum tendons in both right and left legs were excised and used as specimens for tendon healing (n = 8) and control (n = 8), respectively. Each specimen was examined by SHG imaging, followed by tensile testing, and the results of the two testing modalities were assessed for correlation. Results While the SHG light intensity of the healing tendon samples was significantly lower than that of the uninjured tendon samples, 2D Fourier transform SHG images showed a clear difference in collagen fibre structure between the uninjured and the healing samples, and among the healing samples. The mean intensity of the SHG image showed a moderate correlation (R2 = 0.37) with Young’s modulus obtained from the tensile testing. Conclusion Our results indicate that SHG microscopy may be a potential indicator of tendon healing

医療応用を対象とした水中パルス放電により誘起される衝撃波に関する研究

熊本大

Raman Scattering of Inorganic Fibers

We have examined evolution of Raman spectra of carbon fibers and SiC fibers through structural transformations caused by heat treatment. Raman spectra of the SiC fibers indicate that the fibers consist of amorphous or microcrystalline SiC and graphitic microcrystals. We discuss the correlation between the tensile strength of the fibers and their microscopic structure deduced from the Raman data