Management of Ekakushta vis-à-vis Chronic Plaque Psoriasis with Guduchi Kwatha and Karanja Taila - A Clinical Study

The prevalence of skin diseases in general population has varied from 7.86% to 11.16% in various studies. All the skin diseases in Ayurveda have been discussed under the umbrella of “Kushta”. Kushta is further divided into Mahakushta and Kshudrakushta. Ekakushta is considered as one among the Kshudrakushta and it is Vata-Kapha Pradhana Vyadhi having Lakshana like Aswedana, Mahavastu and Matsya Shakalavat Twacha. Psoriasis is one of the most intriguing and perplexing disorder of skin. It is a papulosquamous disorder of the skin, characterised by sharply defined erythematous plaque lesions.  It is notoriously chronic and is well known for its cause or remission and exacerbation. Even though it is considered as an autoimmune disorder affecting the skin, it cannot always be treated as a somatic lesion, it is in fact multifactorial in origin and conditioned by various constitutional and environmental factors. A survey conducted by the National Psoriasis Foundation reports that, almost 75% of patients believe that psoriasis had moderate to large negative impact on their quality of life (QOL) with alterations in their daily activities. Guduchi Kwatha along with Karanja Taila which is specifically mentioned in Kushta Chikitsa, taken as intervention after the Virechana Karma

Progression of a hepatosplenic gamma delta T-cell leukemia/lymphoma on hyperCVAD/MTX and ara-C: literature review and our institutional treatment approach

A 24-year-old male presented with abdominal pain, fever, and palpable splenomegaly. His differential count revealed myelocytes, metamyelocytes, and nucleated red cells. A bone marrow biopsy confirmed a diagnosis of hepatosplenic gamma delta T-cell leukemia/lymphoma. We describe here our center\u27s diagnostic and treatment approach for this rare leukemia

Comparative Study of Different Techniques in Speaker Recognition: Review

The speech is most basic and essential method of communication used by person.On the basis of individual information included in speech signals the speaker is recognized. Speaker recognition (SR) is useful to identify the person who is speaking. In recent years speaker recognition is used for security system. In this paper we have discussed the feature extraction techniques like Mel frequency cepstral coefficient (MFCC), Linear predictive coding (LPC), Dynamic time wrapping (DTW), and for classification Gaussian Mixture Models (GMM), Artificial neural network (ANN) Support vector machine (SVM)

Distribution of Rationing using Automation like RFID and GSM Technology

Ration Card is very important for govt to keep log and other information about people. It is also useful for people to get govt subsidy, gas connection and even useful for residential proof. It has detail about every member in family. All the people use ration card to buy various things from ration shop like groceries,oil, kerosene. This system helps people to get this supplies at low price directly from government. This system has some drawbacks like the most of work is done by old or traditional instruments and mostly its manual work which gives many errors in measurement , and if people fail to buy their monthly subsidy then these shopkeepers sell this to other people at higher price and make money. All this happens because there is no centralized technical database for this information. The loss in this process is of people and govt who don’t have any idea about all this. Our main objective here is to make this process automatic .In this paper, proposed an Automatic Ration Materials Distribution Based on GSM (Global System for Mobile) and RFID (Radio Frequency Identification) technology instead of ration cards. When people come to ration shop they have to scan their RFID card,these cards are magnetic and has information of the beneficiary . After scanning card it is verified through database to see if it is valid or not . Whenever the user logins in system they send an otp to registered number for security purpose. If its valid then the beneficiary selects material and quantity . After receiving these material the customer pays for it. In this way we can create transparency in this process

Management of Vyanga Vis-A-Vis Melasma Through Ayurveda- A Case Series

Melasma is a skin condition characterized by dark spots and patches on the nose, cheeks, forehead and jaw line. Although it is completely harmless, it causes skin discoloration which is difficult to fade away with routine skin care. Melasma can lead to social isolation and stigmatization adversely affecting the quality of daily life which definitely has a major impact on individual’s psychological state and social relationship. The symptomatology of Vyanga given in various available Ayurvedic classics are Mandala (circular patches), Shyava (brown), Tanu (thin), Niruja (painless), etc. The clinical features of melasma can be correlated with Vyanga and condition can be treated based on the Vyanga Chikitsa.      Objectives: To evaluate the efficacy of Haritakyadi Lepa in the management of Vyanga and to review the etiopathology and the clinical aspect of the Vyanga. Result: Based on the collected data, efforts were made to evaluate the efficacy of Haritakyadi Lepa followed by Sadyo Virechana with Manibhadra Guda in the subjects of melasma vis-à-vis Vyanga. Conclusion: In contemporary science, topical steroids have been described in the management of melasma. Alternative to that Haritakyadi Lepa along with Madhu selected for treatment, has shown very effective result in Vyanga

A Rare Case of Metastatic Desmoplastic Small Round Cell Tumour: Diagnosis and Management

A 26-year-old male without any significant past medical history presented to the hospital with shortness of breath, cough, pleuritic chest pain, and weight loss for the past 3 months. On chest CT, he was found to have extensive mediastinal and hilar lymphadenopathy and multiple pulmonary nodules. On physical examination, a right groin mass was noted which had been slowly growing for the past 2 years. Ultrasound of the groin showed complex solid mass with internal vascular channels. CT guided biopsy of the mass showed desmoplastic small round cell tumour. His hospital course was complicated by hypoxic respiratory failure requiring emergent intubation and ICU admission where he completed one cycle of vincristine, cyclophosphamide, and doxorubicin with subsequent improvement, followed by extubation. His condition continued to improve after second cycle of chemotherapy and he was ultimately discharged in a stable condition to continue outpatient chemotherapy after a 2-month inpatient stay

The Impacts of Artificial Intelligence on Research in the Legal Profession

Legal research is an indispensable skill for lawyers. Therefore, it is always necessary for lawyers to engage in legal research in due course of solving various legal problems. Although the purpose and methodology of the research may vary from lawyer to lawyer, doing research is a common activity. On the other hand, the quest to assess the impacts of artificial intelligence (hereinafter 'AI') on legal research allows one to measure the influence of AI on the legal profession in general. Moreover, with the advent of Legal AI, it is now evident that the legal profession is not immune from disruption. Accordingly, this article discusses the impacts of AI on research in the legal profession in general in accomplishing various lawyerly tasks by different legal professionals. The aim of the study is to discuss the current and future positive and negative impacts of AI on research in the legal profession. The study is qualitative in nature and it predominantly relies on document analysis of the relevant primary and secondary sources. Accordingly, the study finds that research in the legal profession is not immune from the impacts of AI and AI influences research in the legal profession, both positively and negatively in enumerable ways. Moreover, it is found that the positive impacts of AI are far greater than its negative externalities, which are usually temporary and related to the disruptive effects of technology on the legal profession. In the future, with the advent of Strong AI, the impact of AI on legal research will be far greater than mere automation

Progression of a hepatosplenic gamma delta T-cell leukemia/lymphoma on hyperCVAD/MTX and ara-C: literature review and our institutional treatment approach

A 24-year-old male presented with abdominal pain, fever, and palpable splenomegaly. His differential count revealed myelocytes, metamyelocytes, and nucleated red cells. A bone marrow biopsy confirmed a diagnosis of hepatosplenic gamma delta T-cell leukemia/lymphoma. We describe here our center\u27s diagnostic and treatment approach for this rare leukemia