Reconciliation and Representation: The Share of the Population Represented by the Democratic Majority

With the debate over health care dragging on, it is becoming increasingly likely that the Senate will pass a bill through the reconciliation process, requiring just a simple majority rather than the super-majority needed to break a filibuster. This paper shows that if this path is taken, senators who represent the vast majority of the nation's population will have supported the bill. This assessment holds even if several of the senators who have indicated serious reservations end up voting against it

The High Budgetary Cost of Incarceration

The United States currently incarcerates a higher share of its population than any other country in the world. We calculate that a reduction in incarceration rates just to the level we had in 1993 (which was already high by historical standards) would lower correctional expenditures by $16.9 billion per year, with the large majority of these savings accruing to financially squeezed state and local governments. As a group, state governments could save$7.6 billion, while local governments could save $7.2 billion. These cost savings could be realized through a reduction by one-half in the incarceration rate of exclusively non-violent offenders, who now make up over 60 percent of the prison and jail population. A review of the extensive research on incarceration and crime suggests that these savings could be achieved without any appreciable deterioration in public safety

The High Budgetary Cost of Incarceration

The United States currently incarcerates a higher share of its population than any other country in the world. We calculate that a reduction in incarceration rates just to the level we had in 1993 (which was already high by historical standards) would lower correctional expenditures by $16.9 billion per year, with the large majority of these savings accruing to financially squeezed state and local governments. As a group, state governments could save$7.6 billion, while local governments could save $7.2 billion. These cost savings could be realized through a reduction by one-half in the incarceration rate of exclusively non-violent offenders, who now make up over 60 percent of the prison and jail population. A review of the extensive research on incarceration and crime suggests that these savings could be achieved without any appreciable deterioration in public safety.incarceration, prison, jail, incarceration rates, budget deficit

State Efforts to Collect Child Outcomes Data for the Part B-619 and Part C Programs Under the Individuals with Disabilities Education Act

The Part B-619 and Part C Programs under the Individuals with Disabilities Education Act (IDEA) provide preschool special education and early intervention services, respectively, to children with disabilities birth through age 5. Recent requirements in IDEA require states to monitor the implementation of these programs through a series of indicators, one of which focuses on the outcomes that infants, toddlers, and preschoolers make as a result of program participation. Known commonly as child outcomes, these data will be used to evaluate the effectiveness of the Part B-619 and Part C programs. The purpose of this investigation was to determine how Part B-619 and Part C programs are collecting high-quality child outcomes data, what barriers these programs are facing in this collection, and how programs are addressing these barriers. Telephone interviews were used to gather descriptive information from a national sample of Part B-619 and Part C coordinators. The clarity and scope of the interview was improved through Dillman's (2000) pretest procedures. The final interview consisted of open-ended questions and was standardized to elicit consistent information from each respondent (Patton, 1990). The results of the study showed that state Part B-619 and Part C programs used similar methods to support the accurate and reliable collection of child outcomes data. Most frequently noted methods included training, a statewide measurement approach, and data review. Despite these methods, 18 types of barriers emerged from collection efforts. Barriers primarily pertained to data quality and the transmission of child outcomes data from local programs to the state. States chose to address barriers through the methods used to support high-quality collection efforts, most notably training and the use of communication and collaboration. Findings suggest that states have established a structure to coordinate the collection of child outcomes data statewide. These efforts focused primarily on improving the quality of these data. Barriers related to the quality of the data emerged despite these efforts, which further indicate the need for ongoing support to sustain high-quality collection efforts. These findings emphasize the importance of training and continuous monitoring to ensure the quality of child outcomes data in statewide collection efforts

Multitier Biometric Template Security Using Cryptographic Salts and Personal Image Identification

Individual identification can be accurately done by measuring biological parameters termed as biometrics. These have been proved as an exceptional tool for identity verification. Security of biometric template is the most challenging aspect of biometric identification system. Storing the biometric template in the database increases the chance of compromising it which may lead to serious threat and misuse of the individual identity. This paper proposes a novel and computationally simpler approach to store a biometric sample in the form of template by using cryptographic salts. Use of Personal Image Identification (PII) makes the proposed algorithm more robust and adds another level of security. The saltcrypted templates are created and stored instead of storing the actual sample behaving as a fuzzy vault. The algorithm has been analytically proved computationally simple compared to the existing template security mechanisms. The fuzzy structure of saltcrypted template is entirely dependent on user interaction through PII. Actual template is not stored at any point of time which adds new dimension to the security and hence to individual identity

How Homocysteine Modulates the Function of Osteoblasts and Osteocytes

Over the years, numerous mechanisms have been identified through which homocysteine affects osteoblast functioning. These include alterations in collagen structure, epigenetic modifications and changes in RANKL-OPG production by osteoblasts. These mechanisms are reviewed in this chapter. We have also herein discussed how homocysteine affects osteocyte behavior. With onset of hyperhomocysteinemia induction of osteocyte specific genes particularly the mineralization genes like Dmp1 and Sost is facilitated producing untoward mineralization, osteocyte apoptosis, deviations from regular bone remodeling process and onset of targeted remodeling in bone. These modifications have immense effect on the overall mechanical stability of bone. Homocysteine thus represents an independent risk factor for bone fragility

Exploiting bacterial isolates for diesel degrading potential under in vitro conditions

Hydrocarbon contaminated oil-spilled areas and oil-products have caused serious harm with increasing attention for development, implementation and removal of these contaminants. Bacterial diversity on succession at the petroleum hydrocarbon contaminated environment can give answer the problem. Such lands have serious problems as totally barren or with rare plantation. Bacteria can thereby be exploited for the mitigation of hydrocarbon to enhance the nutrient availability for vegetation. Present study involves collection of soil samples heavily contaminated with hydrocarbon from Bagru (Rajasthan). Samples were analysed by solid liquid extraction method followed by FTIR (Fourier Transform Infrared) and HPLC (High Performance Liquid Chromatography) analysis. During microbiological analysis hydrocarbon degrading bacteria were screened. FTIR spectral analysis indicated the presence of the functional group’s alkanes and aromatic ringed compounds; 43% to 69% hydrocarbon content recorded by HPLC analysis of all the soil samples respectively. From the soil samples six gram-positive and four gram-negative bacterial isolates were explored possessing hydrocarbon degrading capacities in the range 47.04-87.31% and 10.12-95.24% respectively. Growth kinetic studies revealed the degradation up to 1000 ppm diesel in 3 days under in vitro conditions. These bacteria can further be exploited for diesel degradation and will certainly propose a possible solution to the prevailing issue for its biodegradation in ex-situ conditions after up scaling

Evaluation of maternal serum levels of cell adhesion molecules and endothelial inflammatory markers in normal pregnancy, gestational hypertension and pre-eclampsia

Background: Hypertensive disorders complicate 5 to 10% of all pregnancies. Despite the still unexplained pathogenesis, endothelial dysfunctions and inflammatory mediators are thought to be responsible for the pathogenesis gestational hypertension and pre-eclampsia. Aims and objective of the study was to determine the serum levels of cell adhesions molecules - VCAM-1 and ICAM-1 and endothelial inflammatory markers TNF-α and homocysteine in normal pregnancies, Gestational Hypertension and in Pre-eclampsiaMethods: The cross-sectional study was carried out in Department of Obstetrics and Gynecology and Biochemistry, ESI-PGIMSR, New Delhi between October 2013-April 2015. 150 patients who gave informed written consent were enrolled and were divided equally in three groups of 50 each (normotensive, gestational hypertensive and pre-eclamptic patients). Three groups have been compared in terms of variables such as age, BMI, gestational age, systolic and diastolic blood pressure, platelet count, AST, ALT, mode of delivery, neonatal weight, VCAM-I, ICAM-I, homocysteine and TNF-alpha concentrations.Results: We found the higher concentrations of vascular cell adhesions molecules (VCAM-1 and ICAM-1) and inflammatory mediators (homocysteine and TNF α) in gestational hypertensive patients and in pre-eclamptic patients. Out of four markers, concentrations of ICAM-1 was found in largest proportions and it was also statistical significant. P value was <0.001. Though in our study concentration VCAM-1, homocysteine and TNF-α were also high in gestational hypertensive groups as compared with normotensive patients, but they were not statistical significant.Conclusions: We conclude that higher concentrations of vascular cell adhesions molecules and inflammatory mediators may be responsible for hypertensive disorders of pregnancy suggesting the role of endothelial dysfunction as a central pathogenic feature in development of preeclampsia

Natural Phyto-Active Antihyperglycemic Moieties as Preventive Therapeutics for Diabetes Type II

Diabetes mellitus type II (DM II) is a state characterized by hyperglycemia as fallout of endocrine dysfunction. This condition comes under the category of lifestyle diseases. The impaired insulin secretion, resistance or a combination of both results in the dysregulation of carbohydrate, protein and lipid metabolism. The extremities of this state are associated with other detrimental complications such as cardiomyopathy, retinopathy, nephropathy, hepatopathy, neuropathy etc. DM II has now become a growing epidemic and a major health concern globally. Naturopathy deals with the development of promising therapeutics using herbal origin to ensure minimal or no other side effects with best efficacy of the drug as a promising candidate against a diseased condition. Therefore the review aims to find out a range of medicinal plants that can be used as a natural remedy for the management of DM II, through isolation of active plant moieties (specifically proteins) with antihyperglycemic properties. The active plant metabolites, with antidiabetic potential based on the available pharmacological reports are used as herbal cure against DM II. These isolated active plant moieties, possessing antihyperglycemic properties, might play a significant role in the development of a formulation of plant protein moieties (as a preventive therapeutic) to reduce the prevalence of DM II and to serve the mankind