A study on abuse of topical corticosteroids in patients who attended dermatology venerology leprosy outpatient department

Background: Topical corticosteroids (TCs) are widely used in the patients affected with dermatoses. Abuse of these agents may cause severe adverse effects. Aim of the study was to study the abuse of TCs in patient who attend Dermatology, Venereology, and Leprosy (DVL) outpatient department. Methods: This prospective observational study was conducted in department of DVL at Rajah Muthiah Medical college, Tamil Nadu during the period of six months from November 2018 to April 2019. The patients were enrolled for the study based on inclusion and exclusion criteria.Results: Totally 50 patients with adverse drug reactions (ADRs) by the abuse of TCs were enrolled for the study. It was found that TCs were abused in all ages and equally in both genders. Nearly 72% of the people used TCs for Tinea infection and 20% of the people used TCs for acne vulgaris. Very high potent TCs such as betamethasone and beclomethasone were abused by 55% of the patient. Tinea incognito (TI) was found as common ADRs by the abuse of TCs (74%). Nearly 88% of the people bought TCs from pharmacies without prescription. Sixteen brands were found as easily accessible and affordable for the patients. Medication adherence were increased by 60% after the patient counselling.Conclusion: This study concludes, TI was found as a common ADR in patients who abused TCs such as betamethasone, beclomethasone and clobetasol. High potent TCs should not be allowed to dispense without prescription. Withdrawal of TCs will reduce the risk of ADRs

Contemporary aspects and Prospects of Pollution-Free Aviation: Concept of Green Skies with Data Analysis

This research paper aims to examine the current state and future of sustainable aviation, electric aviation, and pollution-free aviation. The paper will explore the various technologies and innovations that have been developed to reduce the environmental impact of aviation, including fuel-efficient airplane designs, lightweight materials, and cleaner engines. It will also discuss the potential of electric aviation, which offers a promising alternative to traditional fossil-fueled airplanes. The paper will evaluate the benefits and challenges of these sustainable aviation solutions, and offer recommendations for how the aviation industry can continue to reduce its carbon footprint and minimize its impact on the environment. The findings of this research paper will be of interest to anyone who is invested in creating a more sustainable and environmentally friendly aviation sector

Effect of pH variation on Bandgap and Visible Light Photocatalytic Properties of TiO2 Nanoparticles

Titanium-di-oxide nanoparticles are synthesized via a microwave-assisted solvothermal route for different pH values. The effect of the acidic and basic nature of the solvent due to the pH value is reflected in the crystalline size of the compound. The purpose of this work is to synthesize Titanium dioxide nanoparticles and to observe their application in degrading industrially contaminated water using normal tap water. The crystalline sizes are calculated using XRD analysis and confirmed with HRTEM. The chemical composition and oxidation state are confirmed with XPS studies. Optical properties are carried out with UV-Vis, FTIR, and PL spectra. Photocatalytic studies are carried out to degrade the dye in industrial water. The efficiency of degradation is calculated with the UV-Vis data and formula. The reduction in band gap and high permanence has greatly supported in making it acceptable for photocatalytic activity under visible light. Dependence of time, initial dye concentration, and pH of the dye solution on TiO2 as a catalyst is investigated under the illumination of a visible lamp, and degradation efficiency to the highest of 96.79% has been obtained

Single step synthesis of WO 3 nanoparticles by wire explosion process and its photocatalytic behaviour

From IOP Publishing via Jisc Publications RouterHistory: received 2020-12-21, rev-recd 2021-04-07, oa-requested 2021-04-14, accepted 2021-04-30, open-access 2021-05-11, epub 2021-05-11, ppub 2021-06-01Publication status: PublishedTungsten (W) wires are exploded in oxygen ambience to get tungsten oxide (WO3) nanoparticles (NPs). Energy stored in the capacitors (EC) is used to overcome the sublimation energy of wire. Energy ratio (K, ratio of EC and sublimation energy) and oxygen pressure (P) are two control parameters for the particle phase and morphology in the wire explosion process. X-ray diffraction (XRD) patterns confirmed the partial oxidation of W for low values of K. For K = 2, oxidation increases with increase in P. For K = 10, complete oxidation was achieved irrespective of P. Particles are spherical in shape as observed from scanning electron microscope (SEM) and transmission electron microscope (TEM) micrographs. Particle size follows a log-normal distribution with a least mean size of 24.1 nm. UV-vis diffuse reflectance spectroscopy (DRS) was used to measure the absorbance of NPs (complete WO3 with least mean size) for band gap measurement. The band gap was found to be 2.92 eV (visible region). NPs are used as photocatalyst to degrade aqueous solution of methylene blue (MB) under visible light irradiation. 500 mg l−1 of WO3 NPs were optimum to degrade 10 mg l−1 MB in 120 min

Ciliary body metastasis in a patient with non-small cell lung carcinoma — incidental detection with 18F-FDG PET/CT

Ciliary body metastasis in a case of lung cancer is very rare. Intraocular metastasis by any cancer most commonly involves choroid followed by iris and ciliary body. We present a case of a 71-year-old male with non-small cell lung cancer who was found to have an 18F-FDG avid right lung mass. Incidentally a focus of abnormal increased 18F-FDG uptake was noted in the region of ciliary body in the right eyeball. The findings were confirmed to be a metastatic lesion in ciliary body on Ultrasonography and MRI. Our case depicts this extremely rare occurrence corroborated by various modalities

Prevalence and Impact of Thyroid Disorders on Maternal Outcome in Asian-Indian Pregnant Women

Aims. To establish the prevalence and the effect of thyroid dysfunction on pregnancy outcomes in Asian-Indian population. Subjects and Methods. The study cohort comprised of 483 consecutive pregnant women in the first trimester attending the antenatal clinic of a tertiary center in Mumbai, India. Thyroid hormone levels and thyroid peroxidase antibody were estimated. Patients with thyroid dysfunction were assessed periodically or treated depending on the severity. Subjects were followed until delivery. Results. The prevalence of hypothyroidism, Graves' disease, gestational transient thyrotoxicosis, and thyroid autoimmunity (TAI) was 4.8% (n = 24), 0.6% (n = 3), 6.4 % (n = 31), and 12.4% (n = 60), respectively. Forty percent of the hypothyroid patients did not have any high-risk characteristics. Hypothyroidism and TAI were associated with miscarriage (P = 0.02 and P = 0.001, resp.). Conclusions. The prevalence of hypothyroidism (4.8%) and TAI (12.4%) is high. TAI and hypothyroidism were significantly associated with miscarriage

Effect of Magnetic field on Partial Discharge Initiated by Metallic Particle in Thermally Aged Natural Esters under AC and Harmonic Voltages

This paper reports the experimental and theoretical investigations of particle levitation voltage on thermally aged ester fluid, under AC and harmonic AC voltages, in the presence of both electric and magnetic fields (130 mT and 160 mT). The results indicate a higher sensitivity to identify partial discharge (PD) initiated due to particle movement in aged ester fluids with an ultra-high frequency (UHF) sensor than the fluorescent fiber technique. The cause for the reduction in sensitivity of PD detection due to the fluorescent fiber technique with thermally aged fluid is analyzed using steady-state fluorescent measurement. The reduction in the levitation voltage noticed under high-frequency AC voltages is much more severe than its impact under the fundamental frequency of AC supply voltage. In addition, the presence of a magnetic field reduces the magnitude of levitation voltage substantially. The UHF signals generated due to particle movement-initiated discharges with aged ester fluids indicate a shift in its dominant frequency of 0.9 GHz under the absence of a magnetic field to around 0.6 GHz with the effect of a magnetic field

User`s guide and documentation manual for ``BOAST-VHS for the PC``

The recent advancement of computer technology makes reservoir simulations feasible in a personal computer (PC) environment. This manual provides a guide for running BOAST-VHS, a black oil reservoir simulator for vertical/horizontal/slant wells, using a PC. In addition to detailed explanations of input data file preparation for simulation runs, special features of BOAST-VHS are described and three sample problems are presented. BOAST-VHS is a cost-effective and easy-to-use reservoir simulation tool for the study of oil production from primary depletion and waterflooding in a black oil reservoir. The well model in BOAST-VHS permits specification of any combination of horizontal, slanted, and vertical wells in the reservoir. BOAST-VHS was designed for an IBM PC/AT, PS-2, or compatible computer with 640 K bytes of memory. BOAST-VHS can be used to model a three-dimensional reservoir of up to 810 grid blocks with any combination of rows, columns, and layers, depending on the input data supplied. This dynamic redimensioning feature facilitates simulation work by avoiding the need to recompiling the simulator for different reservoir models. Therefore the program is only supplied as executable code without any source code