e-Information on wires- A First Step towards 2-Terminal Silicon Nanowires for Electronic Memory Devices

The file attached to this record is the author's final peer reviewed version. The Publisher's final version can be found by following the DOI link.Presently, there is a rapid growth of interest in the area of flexible electronics. Benefits such as light weight, durability and low-cost are among the most appealing aspects. However, the high temperatures throughout the fabrication processes are still the main hurdle. In this study, the deposition of silicon nanowires (SiNWs) at low temperature (300˚C) using Tin (Sn) catalyst is studied. Silicon nanostructures have been the centre of research for many years for a number of applications in different areas. Chemical Vapour Deposition (CVD) and other industrial deposition techniques, for the growth of crystalline silicon micro- and nano structures use high temperatures and therefore are not compatible with temperature sensitive substrates. This work utilises a low temperature deposition method for the growth of SiNWs and creates a leeway to use flexible plastic sheets as substrates. The silicon nanowires were deposited by exploiting the Vapour-Liquid-Solid (VLS) material growth mechanism using Plasma Enhanced Chemical Vapour Deposition (PECVD) technique. The suitability of these structures, as an information storage material, for future flash and two terminals non-volatile memory devices are investigated. Strong charge storage behaviour with a retention time up to 5 hours was observed showing great potential for the future memory candidate

Study of radiolabeling of chemically modified bombesines

STUDIUM RADIOAKTIVNÍHO ZNAČENÍ CHEMICKY MODIFIKOVANÝCH BOMBESINŮ Diplomová práce Evangelia Saranti Univerzita Karlova v Praze, Farmaceutická fakulta v Hradci Králové Katedra biofyziky a fyzikální chemie Úkolem této práce bylo stadium radioaktivního značení nového receptorově-specifického peptidu DOTA-Lys3-bombesinu terapeutických radionuklidem Lu-177 a stanovit stabilitu značeného produktu. Nalezené optimální podmínky značení tohoto peptidu jsou tyto: pH 5.0 a inkubace při 42řC po dobu 35-40 minut. Za těchto podmínek byla dosažená radiochemická čistota dostatečná pro biologické testování (vyšší než 97%). Byla testována stabilita značeného produktu uchovaného při 4řC a v přítomnosti řádově vyšších koncentrací kompetitivních ligandů EDTA a DTPA. Peptid uchovaný v lednici byl stabilní minimálně čtyři hodiny od přípravy, studium stability v přítomnosti kompetitivních ligandů ukázalo dobrou stabilitu DOTA-komplexu s luteciem-177. Srovnání metod pro určení radiochemické čistoty značeného peptidu ukázalo větší spolehlivost HPLC analýzy ve srovnání s tenkovrstvou chromatografií.STUDY OF RADIOLABELING OF CHEMICALLY MODIFIED BOMBESINES Diploma Thesis Evangelia Saranti Charles University in Prague, Faculty of Pharmacy in Hradec Kralove Department of Biophysics and Physical Chemistry The aim of this thesis was to study the radiolabeling of new perspective receptor-specific peptide DOTA-Lys3-bombesin with therapeutic radionuclide Lu-177 and to determine the stability of the labeled product. We have found the optimum conditions for radiolabeling of selected peptide: pH 5.0 and incubated at 42ř C for 35-40 minutes. Under these conditions sufficient radiochemical purity for biological testing of substance was achieved (higher than 97%). We tested the stability of the radiolabeled product when it was stored at 4ř C, and both in the environment by an order of magnitude higher concentration of competing ligand EDTA or DTPA. Stored in the refrigerator peptide was stable for at least four hours after preparation, study of stability in an environment of competing ligands showed good stability of the DOTA-complex with lutetium-177. Comparison of methods for determination of radiochemical purity of the radiolabeled peptide showed greater reliability of HPLC analysis compared to thin-layer chromatography.Department of Biophysics and Physical ChemistryKatedra biofyziky a fyzikální chemieFaculty of Pharmacy in Hradec KrálovéFarmaceutická fakulta v Hradci Králov

MODEL MEDIA PEMBELAJARAN UNTUK PEMBELAJARAN JARAK JAUH DALAM KETERAMPILAN MEMBACA MENGGUNAKAN GOOGLE SITES (PENELITIAN PENGEMBANGAN DI KELAS IX SMP MUHAMMADIYAH 31 JAKARTA)

Penelitian ini bertujuan untuk mengembangkan media pembelajaran ‎keterampilan membaca berbasis Google Sites di SMP Muhammadiyah 31 ‎Jakarta. Media ini terdiri dari lima judul materi pada buku bahasa arab SMP ‎Muhammadiyah 31 Jakarta, dua judul materi dari buku Kementerian ‎Agama Republik Indonesia dan tiga judul materi dari buku Mutholaah ‎Alarobiyah. ‎ Peneliti menggunakan metode penelitian pengembangan dengan model ‎ADDIE yang dikembangkan oleh Dick and Carrey yang terdiri dari lima ‎langkah, yaitu: 1) Analisis kebutuhan siswa kelas IX SMP Muhammadiyah ‎‎31 Jakarta terhadap media yang digunakan, 2) Desain produk, 3) ‎Pengembangan produk serta penilaian ahli materi dan ahli media, 4) ‎Implementasi produk kepada siswa kelas IX SMP Muhammadiyah 31 ‎Jakarta, dan 5) Evaluasi produk media Google Sites melalui angket ‎terhadap 60 siswa kelas IX SMP Muhammadiyah 31 Jakarta. ‎ Hasil penilaian ahli materi untuk media yang dihasilkan oleh peneliti ‎memperoleh nilai sebesar 88% yang termasuk dalam kategori “sangat ‎layak” dan hasil penilaian ahli media memperoleh nilai 89,53% yang ‎termasuk dalam kategori “sangat layak”, serta hasil evaluasi dari siswa ‎memperoleh nilai 80% yang termasuk kategori “sangat layak”. Dengan ‎demikian, model media pembelajaran jarak jauh untuk keterampilan ‎membaca bahasa arab berbasis Google Sites layak digunakan sebagai ‎media pembelajaran bahasa arab khususnya dalam keterampilan ‎membaca bahasa arab.‎ ********** ‎ This study aims to develop learning media for reading skills based on ‎Google Sites at Junior High School Muhammadiyah 31 Jakarta. This media ‎consists of five material titles in the Arabic language book of Junior High ‎School Muhammadiyah 31 Jakarta, two material titles from the book of the ‎Ministry of Religion of the Republic of Indonesia and three material titles ‎from the book Mutholaah Al Arabiyah.‎ The researcher uses a development research method with the ADDIE ‎model developed by Dick and Carrey which consists of five steps, namely: ‎‎1) Analysis of the needs of class IX students at Junior High School ‎Muhammadiyah 31 Jakarta for the learning media used, 2) Product design, ‎‎3) Product development through the assessment of material experts and ‎media experts, 4) Product implementation for class IX students of Junior ‎High School Muhammadiyah 31 Jakarta, and 5) Evaluation of Google Sites ‎media products through a questionnaire to 60 students of class IX Junior ‎High School Muhammadiyah 31 Jakarta. ️‎ The results of the material expert assessment for the media produced by ‎the researchers obtained a score of 88% which was included in the "very ‎decent" category and the results of the media expert assessment obtained ‎a score of 89.53% which was included in the "very decent" category, as ‎well as the evaluation results from students get a score of 80% which is ‎included in the "very decent" category. Thus, the distance learning media ‎model for reading Arabic skills based on Google Sites is appropriate to be ‎used as a medium for learning Arabic, especially for Arabic reading skills.

Explainable AI with counterfactual paths

Explainable AI (XAI) is an increasingly important area of research in machine learning, which in principle aims to make black-box models transparent and interpretable. In this paper, we propose a novel approach to XAI that uses counterfactual paths generated by conditional permutations. Our method provides counterfactual explanations by identifying alternative paths that could have led to different outcomes. The proposed method is particularly suitable for generating explanations based on counterfactual paths in knowledge graphs. By examining hypothetical changes to the input data in the knowledge graph, we can systematically validate the behaviour of the model and examine the features or combination of features that are most important to the model's predictions. Our approach provides a more intuitive and interpretable explanation for the model's behaviour than traditional feature weighting methods and can help identify and mitigate biases in the model

Towards a Learning-Aware Application Guided by Hierarchical Classification of Learner Profiles

Learner profiling is a methodology that draws a parallel from user profiling. Implicit feedback is often used in recommender systems to create and adapt user profiles. In this work the implicit feedback is based on the learner's answering behaviour in the Android application UnlockYourBrain, which poses different basic mathematical questions to the learners. We introduce an analytical approach to model the learners' profile according to the learner's answering behaviour. Furthermore, similar learner's profiles are grouped together to construct a learning behaviour cluster. The choice of hierarchical clustering as a means of classification of learners' profiles derives from the observations of learners behaviour. This in turn reflects the similarities and subtle differences of learner behaviour, which are further analysed in more detail. Building awareness about the learner's behaviour is the first and necessary step for future learning-aware applications