Allergic Rhinitis Improvement After Septorhinoplasty in a Sample of Allergic Rhinitis Patients With Septal Deviation: A Quasi-Experimental Study

[Abstract] BACKGROUND: Allergic rhinitis (AR) is a chronic inflammatory disease that affects almost 30% of the adult population. OBJECTIVE: To describe and compare the evolution of symptoms in patients diagnosed with AR and septal deviation prior to and following septoplasty (STP). DESIGN AND SETTING: Quasi-experimental study developed in A Coruña University Hospital. METHODS: Patients aged 18-65 years who had been diagnosed with AR and septal deviation were recruited. Obstruction airflow was evaluated before and after surgery, by means of anterior rhinomanometry (RNM). Severity symptoms and quality of life were assessed using a visual analogue scale (VAS) and the ESPRINT questionnaire, respectively. RESULTS: A total of 50 subjects underwent STP and 42 were included in this study. Their mean age at the time of surgery was 34.16 ± 9.74 years (range 18-64). Significant reductions in mean VAS and ESPRINT were observed after surgery (P < 0.01). These outcomes were considered to represent an overall improvement in quality of life. The RNM results also improved significantly, from mean values of 478.07 ± 165.4 cm3/s before STP to 826.4 ± 175.5 cm3/s afterwards (P < 0.01). CONCLUSIONS: The negative correlations of VAS and ESPRINT with RNM, from before and to after STP, demonstrate the efficacy of scales and questionnaires as objective methods for determining obstruction in the absence of rhinomanometry. Patients with allergic rhinitis and septal deviation showed improvements in obstruction severity and medication use after STP. OBJECTIVE: To describe and compare the evolution of symptoms in patients diagnosed with AR and septal deviation prior to and following septoplasty (STP). DESIGN AND SETTING: Quasi-experimental study developed in A Coruña University Hospital. METHODS: Patients aged 18-65 years who had been diagnosed with AR and septal deviation were recruited. Obstruction airflow was evaluated before and after surgery, by means of anterior rhinomanometry (RNM). Severity symptoms and quality of life were assessed using a visual analogue scale (VAS) and the ESPRINT questionnaire, respectively. RESULTS: A total of 50 subjects underwent STP and 42 were included in this study. Their mean age at the time of surgery was 34.16 ± 9.74 years (range 18-64). Significant reductions in mean VAS and ESPRINT were observed after surgery (P < 0.01). These outcomes were considered to represent an overall improvement in quality of life. The RNM results also improved significantly, from mean values of 478.07 ± 165.4 cm3/s before STP to 826.4 ± 175.5 cm3/s afterwards (P < 0.01). CONCLUSIONS: The negative correlations of VAS and ESPRINT with RNM, from before and to after STP, demonstrate the efficacy of scales and questionnaires as objective methods for determining obstruction in the absence of rhinomanometry. Patients with allergic rhinitis and septal deviation showed improvements in obstruction severity and medication use after STP

Laberintectomía química:protocolo y resultados

We present a prospective study about 10 cases of unilateral incapacitate Meniere Disease (clinical stage II and III), without response at medical treatment during at less one year, with a minimal follow-up of 6 months. We employed injection of buffered gentamicin solution weekly. In 5 patients we add a ventilation tube (VT). Medium of dosage utilised was 3.4 (range = 2- 5). No significant hearing loss and initial oscillopsia was present in any patients, but days after two cases developed transitory oscillopsia. A case of Otorrea occurs in a VT receptor. In nine patients initial control of vertigo was achieved. Average time of stabilisation was 26.89 days (range = 13- 45). We found vertigo recurrence in 3 cases. Average of recurrence presentation was 6.33 months (range = 4-9). Chemical laberintectomy with gentamicin is a therapeutic alternative in the treatment of selected cases of unilateral incapacitate Meniere Disease. Results in VT recipient are similar that patients without no VT.Presentamos un estudio prospectivo en 10 sujetos con enfermedad de Meniere incapacitante unilateral (estadíos clínicos II y III), sin respuesta a tratamiento médico durante un año, con un seguimiento mínimo de 6 meses. Se empleó una solución de Gentamicina tamponada, en dosis semanales. En 5 pacientes se colocó un tubo transtimpánico. El número medio de inyecciones empleadas fue de 3.4 (rango 2-5). No se apreció disminución significativa de la audición, ni oscilopsia inicial en ningún caso, pero 2 sujetos la presentaron posteriormente de forma transitoria. Se presentó un caso de otorrea tras tubo transtimpánico. En 9 pacientes se logró control inicial de la enfermedad con desaparición del vértigo, el tiempo medio hasta la estabilización fue de 26.89 días (13-45 días). Existió recurrencia del vértigo en 3 casos, presentándose ésta a los 6.33 meses (4-9 meses). La laberintectomía química con gentamicina es una alternativa terapéutica en el tratamiento de casos seleccionados de enfermedad de Meniere incapacitante unilateral. La colocación de tubo transtimpánico concomitante no mejora los resultados