8 research outputs found
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Fixed drug eruption related to ibuprofen presenting as giant bullae on the posterior thigh
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Fixed drug eruption related to ibuprofen presenting as giant bullae on the posterior thigh
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Prospective evaluation of complications in dermatologic surgery associated with hypertension Conroy
BackgroundPoorly controlled hypertension is a known risk factor for surgical complications. Objective: This study examines the incidence of complications in participants undergoing Mohsmicrographic surgery (MMS) based on preoperative blood pressure (BP) measurement and investigates the role of potential confounders in the relationship between preoperative BP and postoperative complications.MethodsThis 10-month prospective cohort study at the University of California, San Francisco (UCSF) Dermatologic Surgery Center approached all patients undergoing MMS for participation and assessed for the diagnosis of hypertension, anti-hypertensive medication use, use of tobacco or blood thinners, immunosuppression, concomitant diabetes, or previous treatment with radiation therapy at the surgical site.ResultsPreliminary analysis included 830 people. Overall, 676 patients had their follow up in the Mohs unit. The rate of complications was as follows: postoperative hemorrhage (6, 0.8%), hematoma formation (7, 1.0%), wound infection (16, 2.4%), wound dehiscence (19, 2.8%), flap necrosis (13, 1.9%), graft necrosis (8, 1.2%). Eight patients experienced two complications. There was no significant relationship between a patient’s BP and the presence of complications. In multivariate analyses that include all the potential confounding variables, a self-reported history of diabetes was the only factor that influenced the presence of complications (P=0.039).ConclusionsOur preliminary analysis showed no relationship between BP and the rate of complications, while the presence of diabetes significantly increased a patient’s risk for a wound complication. This study was limited by a relatively small number of complications and more data will be needed to further investigate the relationship
Recommended from our members
Prospective evaluation of complications in dermatologic surgery associated with hypertension Conroy
BackgroundPoorly controlled hypertension is a known risk factor for surgical complications. Objective: This study examines the incidence of complications in participants undergoing Mohsmicrographic surgery (MMS) based on preoperative blood pressure (BP) measurement and investigates the role of potential confounders in the relationship between preoperative BP and postoperative complications.MethodsThis 10-month prospective cohort study at the University of California, San Francisco (UCSF) Dermatologic Surgery Center approached all patients undergoing MMS for participation and assessed for the diagnosis of hypertension, anti-hypertensive medication use, use of tobacco or blood thinners, immunosuppression, concomitant diabetes, or previous treatment with radiation therapy at the surgical site.ResultsPreliminary analysis included 830 people. Overall, 676 patients had their follow up in the Mohs unit. The rate of complications was as follows: postoperative hemorrhage (6, 0.8%), hematoma formation (7, 1.0%), wound infection (16, 2.4%), wound dehiscence (19, 2.8%), flap necrosis (13, 1.9%), graft necrosis (8, 1.2%). Eight patients experienced two complications. There was no significant relationship between a patient’s BP and the presence of complications. In multivariate analyses that include all the potential confounding variables, a self-reported history of diabetes was the only factor that influenced the presence of complications (P=0.039).ConclusionsOur preliminary analysis showed no relationship between BP and the rate of complications, while the presence of diabetes significantly increased a patient’s risk for a wound complication. This study was limited by a relatively small number of complications and more data will be needed to further investigate the relationship
Cutaneous Leishmaniasis in Cuban Immigrants to Texas who Traveled through the Darién Jungle, Panama
Polysubstance Use Among Minority Adolescent Males Incarcerated for Serious Offenses
BACKGROUND: Adolescent juvenile offenders are at high risk for problems associated with drug use, including polysubstance use (i.e., use of a variety of drugs). The combination of juvenile offending and polysubstance use presents a significant public and child health concern. OBJECTIVE: This study explored polysubstance use among a sample of youth incarcerated for serious offenses. We examined several risk factors for substance use and delinquency (i.e., early and frequent substance use, prior history of arrests, school expulsion, Black ethnicity), as well as the association between aggression and polysubstance use. METHODS: Data were collected via questionnaires from 373 serious male juvenile offenders upon intake into a secure locked facility. Youth were on average 16 years old, and minority youth were overrepresented (28.1% Black, 53.1% Latino). Poisson regressions were used to assess the associations between the risk factors, aggression, and polysubstance use. RESULTS: Consistent with the literature, Black youth reported less polysubstance use and later age of drug use onset than White and Latino youth. Findings suggest that Latino juvenile offenders and those with an early and problematic pattern of substance use are at heightened risk for polysubstance use. Aggression was not significantly related to polysubstance use, over and above the risk factors. CONCLUSIONS: Given that Latino youth experience low rates of treatment for substance use, the development of culturally-sensitive interventions for these youth is needed. Interventions should also be multifaceted to address the multitude of risk factors associated with polysubstance use among juvenile offenders