Geographic Variation of Cirques on Iceland: Factors Influencing Cirque Morphology

Cirques are one of the most common glacial landforms in alpine settings. They also provide important paleoclimate information (e.g. Meierding 1984; Evans 2006). The purpose of this study is to fill in gaps in the climate record of Iceland by conducting a quantitative analysis of cirques in three regions in Iceland: Tröllaskagi, the East Fjords, and Vestfirðir. Iceland, located in the center of the North Atlantic Ocean, contains many small glaciers, in addition to large ice caps. The glaciers on Iceland are particularly sensitive to variations in oceanic and atmospheric circulation (Andresen et al. 2005; Geirsdóttir et al., 2009; Ólafsdóttir et al. 2010). Iceland thus provides an excellent case study to examine factors influencing glacial landforms such as cirques. (excerpt

Providing stringent star formation rate limits of z∼\sim2 QSO host galaxies at high angular resolution

We present integral field spectrograph (IFS) with laser guide star adaptive optics (LGS-AO) observations of z=2 quasi-stellar objects (QSOs) designed to resolve extended nebular line emission from the host galaxy. Our data was obtained with W. M. Keck and Gemini-North Observatories using OSIRIS and NIFS coupled with the LGS-AO systems. We have conducted a pilot survey of five QSOs, three observed with NIFS+AO and two observed with OSIRIS+AO at an average redshift of z=2.15. We demonstrate that the combination of AO and IFS provides the necessary spatial and spectral resolutions required to separate QSO emission from its host. We present our technique for generating a PSF from the broad-line region of the QSO and performing PSF subtraction of the QSO emission to detect the host galaxy. We detect H$\alpha$ and [NII] for two sources, SDSS J1029+6510 and SDSS J0925+06 that have both star formation and extended narrow-line emission. Assuming that the majority of narrow-line H$\alpha$ is from star formation, we infer a star formation rate for SDSS J1029+6510 of 78.4 M$_\odot$yr$^{-1}$ originating from a compact region that is kinematically offset by 290 - 350 km/s. For SDSS J0925+06 we infer a star formation rate of 29 M$_\odot$yr$^{-1}$ distributed over three clumps that are spatially offset by $\sim$ 7 kpc. The null detections on three of the QSOs are used to infer surface brightness limits and we find that at 1.4 kpc distance from the QSO that the un-reddened star formation limit is $<$ 0.3 M$_\odot$yr$^{-1}$kpc$^{-2}$. If we assume a typical extinction values for z=2 type-1 QSOs, the dereddened star formation rate for our null detections would be $<$ 0.6 M$_\odot$yr$^{-1}$kpc$^{-2}$. These IFS observations indicate that if star formation is present in the host it would have to occur diffusely with significant extinction and not in compact, clumpy regions.Comment: 17 pages, 7 figures, 7 tables, Accepted to Ap

Bayesian historical earthquake relocation: an example from the 1909 Taipei earthquake

Locating earthquakes from the beginning of the modern instrumental period is complicated by the fact that there are few good-quality seismograms and what traveltimes do exist may be corrupted by both large phase-pick errors and clock errors. Here, we outline a Bayesian approach to simultaneous inference of not only the hypocentre location but also the clock errors at each station and the origin time of the earthquake. This methodology improves the solution for the source location and also provides an uncertainty analysis on all of the parameters included in the inversion. As an example, we applied this Bayesian approach to the well-studied 1909 M_w 7 Taipei earthquake. While our epicentre location and origin time for the 1909 Taipei earthquake are consistent with earlier studies, our focal depth is significantly shallower suggesting a higher seismic hazard to the populous Taipei metropolitan area than previously supposed

The ectodomain of Toll-like receptor 9 is cleaved to generate a functional receptor.

Mammalian Toll-like receptors (TLRs) 3, 7, 8 and 9 initiate immune responses to infection by recognizing microbial nucleic acids; however, these responses come at the cost of potential autoimmunity owing to inappropriate recognition of self nucleic acids. The localization of TLR9 and TLR7 to intracellular compartments seems to have a role in facilitating responses to viral nucleic acids while maintaining tolerance to self nucleic acids, yet the cell biology regulating the transport and localization of these receptors remains poorly understood. Here we define the route by which TLR9 and TLR7 exit the endoplasmic reticulum and travel to endolysosomes in mouse macrophages and dendritic cells. The ectodomains of TLR9 and TLR7 are cleaved in the endolysosome, such that no full-length protein is detectable in the compartment where ligand is recognized. Notably, although both the full-length and cleaved forms of TLR9 are capable of binding ligand, only the processed form recruits MyD88 on activation, indicating that this truncated receptor, rather than the full-length form, is functional. Furthermore, conditions that prevent receptor proteolysis, including forced TLR9 surface localization, render the receptor non-functional. We propose that ectodomain cleavage represents a strategy to restrict receptor activation to endolysosomal compartments and prevent TLRs from responding to self nucleic acids

Reading Performance is Predicted by More Than Phonological Processing

We compared three phonological processing components (phonological awareness, rapid automatized naming and phonological memory), verbal working memory, and attention control in terms of how well they predict the various aspects of reading: word recognition, pseudoword decoding, fluency and comprehension, in a mixed sample of 182 children ages 8–12 years. Participants displayed a wide range of reading ability and attention control. Multiple regression was used to determine how well the phonological processing components, verbal working memory, and attention control predict reading performance. All equations were highly significant. Phonological memory predicted word identification and decoding. In addition, phonological awareness and rapid automatized naming predicted every aspect of reading assessed, supporting the notion that phonological processing is a core contributor to reading ability. Nonetheless, phonological processing was not the only predictor of reading performance. Verbal working memory predicted fluency, decoding and comprehension, and attention control predicted fluency. Based upon our results, when using Baddeley’s model of working memory it appears that the phonological loop contributes to basic reading ability, whereas the central executive contributes to fluency and comprehension, along with decoding. Attention control was of interest as some children with ADHD have poor reading ability even if it is not sufficiently impaired to warrant diagnosis. Our finding that attention control predicts reading fluency is consistent with prior research which showed sustained attention plays a role in fluency. Taken together, our results suggest that reading is a highly complex skill that entails more than phonological processing to perform well