Sturge Weber Syndrome Diagnosed at Late Age, Associated with Psychiatric Complaints and Status: A Case Report

Sturge-Weber syndrome (SWS) is a rare, sporadic neurocutaneous syndrome characterized by a usually unilateral facial port-wine stain, ipsilateral leptomeningeal angiomatosis, glaucoma, epileptic seizures that are difficult to control, and progressive cerebral dysfunction. A 41-year-old woman presented with headache, nausea, vomiting, and a speech disorder. On examination a lesion on the right side of her face consistent with hemangioma was noted, as well as a high fever, hyperglycemia, and tonsillitis. Electroencephalography revealed a paroxysmal abnormality in the right frontotemporal region, and contrast-enhanced cranial magnetic resonance imaging revealed vascularization and dural contrast enhancement in the right cerebral hemisphere. The patient was diagnosed with SWS and discharged with acetylsalicylic acid (ASA) and valproic acid therapy, but returned 2 weeks later with tonic-clonic status epilepticus. The seizures were controlled with an infusion of diazepam in the intensive care unit and the dosage of valproic acid was increased. Aripiprazole was initiated for visual and auditory hallucinations. The patient was discharged after 10 days with a normal neurological examination and follow-up has not revealed any seizure or sequel findings with the ASA and valproic acid therapy

Sensitivity with respect to smoothing limit.

<p>(A) Smoothing Limit vs Total Cost. (B) Smoothing Limit vs Social Cost. (C) Smoothing Limit vs Subcontracting Cost.</p

Sensitivity with respect to overtime limit.

<p>(A) Overtime Limit vs Total Cost. (B) Overtime Limit vs Social Cost. (C) Overtime Limit vs Subcontracting Cost.</p

Percentage Change According to Different Models.

<p>Percentage Change According to Different Models.</p

Sustainability in Supply Chain Management: Aggregate Planning from Sustainability Perspective

<div><p>Supply chain management that considers the flow of raw materials, products and information has become a focal issue in modern manufacturing and service systems. Supply chain management requires effective use of assets and information that has far reaching implications beyond satisfaction of customer demand, flow of goods, services or capital. Aggregate planning, a fundamental decision model in supply chain management, refers to the determination of production, inventory, capacity and labor usage levels in the medium term. Traditionally standard mathematical programming formulation is used to devise the aggregate plan so as to minimize the total cost of operations. However, this formulation is purely an economic model that does not include sustainability considerations. In this study, we revise the standard aggregate planning formulation to account for additional environmental and social criteria to incorporate triple bottom line consideration of sustainability. We show how these additional criteria can be appended to traditional cost accounting in order to address sustainability in aggregate planning. We analyze the revised models and interpret the results on a case study from real life that would be insightful for decision makers.</p></div

Sensitivity with respect to the service level.

<p>(A) Service Level vs Total Cost. (B) Service Level vs Social Cost. (C) Service Level vs Subcontracting Cost.</p

Impact of Electrical Stimulation on Rehabilitation Process in Peripheral Facial Paralysis

Aim: The purpose of this study is to discuss the efficiency of electrical stimulation in the treatment of facial paralysis, and its contribution to the rehabilitation process and, its impact on recovery. Material and methods: 18 cases were enrolled into the study who were diagnosed with ficial paralysis and consulted within the first month, and have been receiving medical treatment. Home exercise program was given to all patients. The first group was followed-up with hospital rehabilitation program that included electrical stimulation, while the second group was organized to recieve only home exercise program. Functional response to treatment was assessed by the House-Brackmann scale grading system. Results: House-Brackmann scale scores of rehabilitation program and electrical stimulation patient group, were compared pre-and post-treatment, clinical improvement was observed more significantly in the 6th week. There. was no significant difference between House-Brackmann scale scores in pre-treatment and the 69 week visits of the patients in home exercise program group (p = 0.16). However, the Houser-Brackmann scale scores were detected to be statistically significantly different between pre-and 6 months after the treatment in both of the treatment groups (p = 0.005). Conclusion: As a result, the recovery time is faster in the patients treated with the rehabilitation group that includes electrical stimulation. Therefore electrical stimulation therapy is an acceptable effective method for the treatment of facial paralysis, nonetheless this should be investigated in larger patient groups, in future

Some molecular properties and reaction mechanism of synthesized isatin thiosemicarbazone and its zinc(II) and nickel(II) complexes

The aim of this study is to 1H-Indole-2,3-dione 3-[N-(4-fluorophenyl)-thiosemicarbazone and its&nbsp;zinc(II) and nickel(II) complexes. The structures of the synthesized compounds were confirmed by&nbsp;spectral data and elemental analysis. They were optimized by B3LYP theory with different basis&nbsp;sets. The optimized structures were compared with the experimental values. TD-DFT calculationson electronic absorption spectra in gas phase and DMSO were performed to determine the&nbsp;electronic transitions of the compounds. The Frontier Molecular Orbital analysis were also done inorder to identify the charge transfer interaction that takes place between the molecular orbitals.&nbsp;Reaction mechanism of 1H-indole-2,3-dione-3-(N-4-fluorophenyl&nbsp;thiosemicarbazone) molecules&nbsp;were also studied.</p