Integrated payload and mission planning, phase 3. Volume 1: Integrated payload and mission planning process evaluation

The integrated payload and mission planning process for STS payloads was defined, and discrete tasks which evaluate performance and support initial implementation of this process were conducted. The scope of activity was limited to NASA and NASA-related payload missions only. The integrated payload and mission planning process was defined in detail, including all related interfaces and scheduling requirements. Related to the payload mission planning process, a methodology for assessing early Spacelab mission manager assignment schedules was defined

Einführung in die deutsche Linguistik / Introduction to German Linguistics

This book is an introduction to the study of German linguistics, for students whose native language is not German. Although there are many introductions to German linguistics, this is the first one that is written with intermediate-level second-language learners in mind. The book, therefore, has two primary goals: to introduce students to formal linguistics as it applies specifically to German, and to foster second language acquisition of German by connecting linguistic analysis to practical exercises in pronunciation, grammar, sociolinguistics, etc.https://egrove.olemiss.edu/open/1000/thumbnail.jp

Food with Integrity?: How Responsible Corporate Officer Prosecutions Under the Federal Food, Drug, and Cosmetic Act Deny Fair Warning to Corporate Officers

[W]hen it comes to food safety, we have to rely on the companies that manufacture and distribute food to ensure that the food we buy is safe. In fact, most consumers give little thought to the safety of their food. I know I don’t and I bet many of you don’t either. We simply don’t expect to get sick from the food at our favorite restaurant, or from peanut butter or the eggs or the cantaloupes or the countless other products that we buy at the supermarket. That is why food safety is a priority for the Justice Department. Our role in protecting consumer safety is at its apex when consumers can least protect themselves.

Murky Waters: Barriers to Recovery for Flood Damage from Municipal Waterworks

The State has long enjoyed an exception to the general rules of negligence liability under the common law doctrine of sovereign immunity. This immunity has been extended to municipal governments in carrying out their role of serving the general public but not in their performance of proprietary functions. In its ruling in Junior College District v. City of St. Louis,2 the Missouri Supreme Court emphasized the narrow interpretation of exceptions to limits on negligence claims against government entities, particularly in relation to a municipality\u27s operations as a provider of water to its citizens.3 The court further insulated municipal water suppliers by refusing to recognize a duty owed by a municipality to take reasonable measures to stop the flood of water onto private property as a result of a failure in an instrumentality not owned or maintained by the municipality.

The Role of Religious and Spiritual Beliefs in the Academic Success of College Students

The college environment can be very demanding for students. Students are often challenged by many new experiences as they adjust to their new environment and learn to balance their academic responsibilities and social life. Previous research has examined two factors, religiosity and spirituality, that can contribute to the academic success of college students. The present study was conducted to examine the correlation between religiosity and spirituality and college students’ grade point averages (GPA) which was operationally defined to measure academic success. It was hypothesized that higher levels of religiosity and spirituality would correlate with higher GPAs. Participants were asked to complete three scales of measurement to assess their religious and spiritual behaviors, as well as a demographics survey. Results indicated a negative correlation between religiosity and spirituality and student GPAs. Future research should explore what factors influenced negative correlations between religiosity, spirituality and GPAs

Technical Communication, Participatory Action Research, and Global Civic Engagement: A Teaching, Research, and Social Action Collaboration in Kenya.

In response to recent calls for internationalization and greater social relevance in professional communication teaching and research, this article links service-learning pedagogy with participatory action research (PAR) methods. A multi-year collaborative project in Kenya illustrates both the challenges and the positive outcomes of international partnerships, which include increased intercultural communication skills, significant contributions to the literature, invigoration of teaching and curriculum, and the development of global civic awareness among all participants. In their recommendations for faculty interested in developing similar partnerships, the authors highlight the importance of understanding the theoretical foundations of servicelearning pedagogy and PAR methods, and advocate for the incorporation of exploratory site visits, pre-departure preparation for both students and faculty, critical reflection, efforts to ensure reciprocal benefits, and ongoing outcomes assessment

Experiment K-6-16. Morphological examination of rat testes. The effect of Cosmos 1887 flight on spermatogonial population and testosterone level in rat testes

Testes from rats flown on Cosmos 1887 for twelve and a half days were compared to basal control, synchronous control and vivarium maintained rats. When the mean weights of flight testes, normalized for weight/100 gms, were compared to the vivarium controls they were 6.7 percent lighter. Although the flight testes were lighter than the synchronous, the difference is not significant. Counts of spermatogonial cells from 5 animals in each group revealed a 4 percent decrease in flight compared to vivarium controls. In both cases the t-Test significance was less than 0.02. The serum testosterone levels of all animals (flight, synchronous and vivarium) were significantly below the basal controls

Characterization of neutralizing epitopes within the major capsid protein of human papillomavirus type 33

BACKGROUND: Infections with papillomaviruses induce type-specific immune responses, mainly directed against the major capsid protein, L1. Based on the propensity of the L1 protein to self-assemble into virus-like particles (VLPs), type-specific vaccines have already been developed. In order to generate vaccines that target a broader spectrum of HPV types, extended knowledge of neutralizing epitopes is required. Despite the association of human papillomavirus type 33 (HPV33) with cervical carcinomas, fine mapping of neutralizing conformational epitopes on HPV33 has not been reported yet. By loop swapping between HPV33 and HPV16 capsid proteins, we have identified amino acid sequences critical for the binding of conformation-dependent type-specific neutralizing antibodies to surface-exposed hyper variable loops of HPV33 capsid protein L1. RESULTS: Reactivities of monoclonal antibodies (mAbs) H33.B6, H33.E12, H33.J3 and H16.56E with HPV16:33 and HPV33:16 hybrid L1 VLPs revealed the complex structures of their conformational epitopes as well as the major residues contributing to their binding sites. Whereas the epitope of mAb H33.J3 was determined by amino acids (aa) 51–58 in the BC loop of HPV33 L1, sequences of at least two hyper variable loops, DE (aa 132–140) and FGb (aa 282–291), were found to be essential for binding of H33.B6. The epitope of H33.E12 was even more complex, requiring sequences of the FGa loop (aa 260–270), in addition to loops DE and FGb. CONCLUSION: These data demonstrate that neutralizing epitopes in HPV33 L1 are mainly located on the tip of the capsomere and that several hyper variable loops contribute to form these conformational epitopes. Knowledge of the antigenic structure of HPV is crucial for designing hybrid particles as a basis for intertypic HPV vaccines

Fitness and Metabolic Syndrome Components Affect Serum-Induced Endothelial Migration and MicroRNAs in Postmenopausal African-American Women

Please download pdf version here