271 research outputs found
Real map germs and higher open books
We present a general criterion for the existence of open book structures
defined by real map germs (\bR^m, 0) \to (\bR^p, 0), where , with
isolated critical point. We show that this is satisfied by weighted-homogeneous
maps. We also derive sufficient conditions in case of map germs with isolated
critical value.Comment: 12 page
Evaluation of the cardiovascular effects of vasicine, an alkaloid isolated from the leaves of Sida cordifolia L. (Malvaceae)
The cardiovascular effects of vasicine, an alkaloid isolated from the leaves of Sida cordifolia L., were evaluated in this work. In non-anaesthetized rats (n=6), vasicine (1, 2.5, 5 and 10 mg/kg; i.v., randomly) induced hypotension associated with an intense bradycardia. Both responses were completely abolished after atropine (2mg/Kg; i.v.) and attenuated after hexamethonium (20 mg/Kg; i.v.). In isolated rat mesenteric artery rings, vasicine (0.03, 0.1, 0.3, 1, 3, 10, 30, 100 and 300 μg/mL, cumulatively) induced concentration-dependent relaxation of phenylephrine-induced tone (IC50= 3.8±0.9 μg/mL; n = 6). In conclusion, the results show that vasicine produce hypotension and bradycardia which appears to be due to the stimulation of cardiac muscarinic receptors (directly and/or indirectly), and by a decrease of the peripheral resistances
Singular open book structures from real mappings
We prove extensions of Milnor's theorem for germs with nonisolated
singularity and use them to find new classes of genuine real analytic mappings
with positive dimensional singular locus \Sing \psi \subset
\psi^{-1}(0), for which the Milnor fibration exists and yields an open book
structure with singular binding.Comment: more remark
Orelha de Elefante Mexicana (Opuntia stricta [Haw.] Haw.) spineless cactus as an option in crossbred dairy cattle diet
new genotype of spineless cactus is being used in the diets of dairy cattle that are raised in semi-arid regions. However, little is known about its nutritional value. This study aimed to evaluate the effects of replacing Miúda (Nopalea cochenillifera Salm Dyck) with Orelha de Elefante Mexicana (Opuntia stricta [Haw.] Haw.) spineless cactus, on nutrient intake and digestibility, milk yield and composition, feeding behaviour, microbial protein synthesis, nitrogen balance, and ruminal and blood parameters of dairy cows. Ten Girolando cows, 500 ± 51.6 kg bodyweight, were distributed in a double Latin square design 5 x 5. The treatments consisted of replacement levels of Miúda (MIU) by Orelha de Elefante Mexicana (OEM) at 0, 25, 50, 75, and 100%. The intake and digestibility of dry matter (DM) (14.38–12.95 kg d-1, 716.3–658.9 g d-1), organic matter (OM) (13.01–11.43 kg d-1, 747.8–704.8 g d-1), crude protein (CP) (2.02–1.61 kg d-1, 863.8–845.2 g d-1) and total digestible nutrients (TDN) (9.38–7.92 kg d-1) decreased linearly with the increase in replacement. Despite the decrease in intake and digestibility, the supply of nutrients was sufficient to maintain a milk yield of 12.5 kg d-1. The average daily weight gain decreased linearly with the increase in replacement, while protein microbial efficiency (g microbial CP kg-1 TDN intake; 91.24 to 127.44 g kg-1) increased linearly. Thus, OEM could replace 100% MIU in diets with 48% of spineless cactus, for crossbred lactating cows with 12.5 kg d-1 milk yield. Therefore, OEM is a viable new option for producing milk in smallholder livestock systems in semi-arid regions.Keywords: Alternative forage, milk yield, ruminal parameter, semi-arid, smallholder livestock syste
Prevalence of Anaemia and Associated Factors among Children below Five Years of Age in Cape Verde, West Africa
This study estimated the prevalence of anaemia and associated factors
in a probability sample of 993 children aged 6-59 months in Cape Verde,
West Africa. Odds ratio (OR) and 95% confidence interval (95% CI) were
estimated from a hierarchical model for multiple analysis to assess the
association between anaemia and explanatory variables. The prevalence
of anaemia was 51.8% (95% CI 47.7-55.8). Children who resided within
poor household conditions (OR 1.99; 95% CI 1.06-3.71) were below 24
months of age (OR 3.23; 95% CI 2.03-5.15) and recently experienced
diarrhoea (OR 1.58; 95% CI 0.99-2.50) were at high risk of anaemia.
Anaemia should be considered a serious public-health concern in Cape
Verde, mainly for children below 24 months. Further, special
consideration should be given to children who have experienced recent
diarrhoea and belong to families residing in poor household conditions
Uso da adubação orgânica e cobertura morta na cultura da calêndula (Calendula officinalis L.).
A calêndula representa fonte alternativa econômica principalmente para a agricultura familiar. O objetivo do presente trabalho foi avaliar os efeitos da adubação orgânica e do uso da cobertura morta sobre a produção de biomassa e teor de flavonóides totais em plantas de calêndula. O experimento foi realizado no Campus de Montes Claros da Universidade Federal de Minas Gerais, utilizando-se o delineamento em blocos casualizados em esquema fatorial 2x2x4 com quatro repetições: duas épocas de colheita, presença ou ausência de cobertura morta e quatro doses de composto orgânico (0, 30, 60 e 90 t ha-1). As maiores produções de biomassa e flavonóides totais foram verificadas com o aumento das doses de composto orgânico. Para os flavonóides totais o maior teor foi obtido na segunda colheita na presença de cobertura morta
Kinin B1 receptor controls maternal adiponectin levels and influences offspring weight gain
Given the importance of the kinin B1 receptor in insulin and leptin hormonal regulation, which in turn is crucial in maternal adaptations to ensure nutrient supply to the fetus, we investigated the role of this receptor in maternal metabolism and fetoplacental development. Wild-type and kinin B1 receptor-deficient (B1KO) female mice were mated with male mice of the opposite genotype. Consequently, the entire litter was heterozygous for kinin B1 receptor, ensuring that there would be no influence of offspring genotype on the maternal phenotype. Maternal kinin B1 receptor blockade reduces adiponectin secretion by adipose tissue ex vivo, consistent with lower adiponectin levels in pregnant B1KO mice. Furthermore, fasting insulinemia also increased, which was associated with placental insulin resistance, reduced placental glycogen accumulation, and heavier offspring. Therefore, we propose the combination of chronic hyperinsulinemia and reduced adiponectin secretion in B1KO female mice create a maternal obesogenic environment that results in heavier pups
Efeito do tratamento de sementes de algodoeiro com fungicidas no controledo tombamento em relação à densidade de inóculo de Rhizoctonia solani
Climate change and future scenarios for palisade grass production in the state of São Paulo, Brazil
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